Identification of novel functional and spatial associations between sphingosine kinase 1, sphingosine 1-phosphate receptors and other signaling proteins that affect prognostic outcome in estrogen receptor-positive breast cancer (Q44501429)

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scientific article published on 11 July 2012

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English	Identification of novel functional and spatial associations between sphingosine kinase 1, sphingosine 1-phosphate receptors and other signaling proteins that affect prognostic outcome in estrogen receptor-positive breast cancer	scientific article published on 11 July 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Identification of novel functional and spatial associations between sphingosine kinase 1, sphingosine 1-phosphate receptors and other signaling proteins that affect prognostic outcome in estrogen receptor-positive breast cancer (English)

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Europe PubMed Central

PubMed publication ID

3 December 2017

estrogen-receptor positive breast cancer

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2

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3 December 2017

author name string

Jan Ohotski

1

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3 December 2017

Beatrix Elsberger

3

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3 December 2017

Carol Watson

4

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3 December 2017

Clare Orange

5

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Europe PubMed Central

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3 December 2017

Elizabeth Mallon

6

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3 December 2017

Susan Pyne

7

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Europe PubMed Central

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3 December 2017

Nigel J Pyne

8

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3 December 2017

language of work or name

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publication date

11 July 2012

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3 December 2017

International Journal of Cancer

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3 December 2017

132

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3

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3 December 2017

605-616

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3 December 2017

Sphingosine 1-phosphate and cancer

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Sphingosine 1-phosphate signalling in mammalian cells

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Principles of bioactive lipid signalling: lessons from sphingolipids

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

The outs and the ins of sphingosine-1-phosphate in immunity

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate.

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Sphingosine‐1‐phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

BACE1 activity is modulated by cell-associated sphingosine-1-phosphate.

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Filamin A links sphingosine kinase 1 and sphingosine-1-phosphate receptor 1 at lamellipodia to orchestrate cell migration

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Sphingosine Kinase Inhibitors and Cancer: Seeking the Golden Sword of Hercules

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21 January 2018

Sphingosine kinase 1 induces tolerance to human epidermal growth factor receptor 2 and prevents formation of a migratory phenotype in response to sphingosine 1-phosphate in estrogen receptor-positive breast cancer cells

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

High Expression of Sphingosine 1-Phosphate Receptors, S1P1 and S1P3, Sphingosine Kinase 1, and Extracellular Signal-Regulated Kinase-1/2 Is Associated with Development of Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer Patients

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer.

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis.

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer MCF-7 cells

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Sphingosine 1-phosphate receptor expression profile in human gastric cancer cells: differential regulation on the migration and proliferation.

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

An oncogenic role of sphingosine kinase

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Guanine nucleotides regulate sphingosine kinase 1 activation by eukaryotic elongation factor 1A and provide a mechanism for eEF1A-associated oncogenesis

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Sphingosine 1-Phosphate Receptor 4 Uses HER2 (ERBB2) to Regulate Extracellular Signal Regulated Kinase-1/2 in MDA-MB-453 Breast Cancer Cells

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Defining a role for sphingosine kinase 1 in p53-dependent tumors.

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Deactivation of sphingosine kinase 1 by protein phosphatase 2A.

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

A critical role for the protein phosphatase 2A B′α regulatory subunit in dephosphorylation of sphingosine kinase 1

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Breast cancer patients' clinical outcome measures are associated with Src kinase family member expression.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

AKT activation predicts outcome in breast cancer patients treated with tamoxifen

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Ras/Raf-1/MAPK pathway mediates response to tamoxifen but not chemotherapy in breast cancer patients

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Outcome and human epidermal growth factor receptor (HER) 1-4 status in invasive breast carcinomas with proliferation indices evaluated by bromodeoxyuridine labelling

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-alpha signaling

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

PKC-dependent activation of sphingosine kinase 1 and translocation to the plasma membrane. Extracellular release of sphingosine-1-phosphate induced by phorbol 12-myristate 13-acetate (PMA)

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Early activation of sphingosine kinase in mast cells and recruitment to FcepsilonRI are mediated by its interaction with Lyn kinase

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Tumor necrosis factor-alpha-stimulated cell proliferation is mediated through sphingosine kinase-dependent Akt activation and cyclin D expression

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Tyrosine phosphorylation of p85 relieves its inhibitory activity on phosphatidylinositol 3-kinase

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibitio

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Distinctive T cell-suppressive signals from nuclearized type 1 sphingosine 1-phosphate G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Ablation of sphingosine kinase-2 inhibits tumor cell proliferation and migration

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Role of sphingosine kinases and lipid phosphate phosphatases in regulating spatial sphingosine 1-phosphate signalling in health and disease

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https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27692

21 January 2018

Identifiers

10.1002/IJC.27692

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

ResearchGate publication ID

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