Inhibitors tethered near the acetylcholinesterase active site serve as molecular rulers of the peripheral and acylation sites (Q44506930)

3 December 2017

title

Inhibitors tethered near the acetylcholinesterase active site serve as molecular rulers of the peripheral and acylation sites (English)

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3 December 2017

Joseph L Johnson

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3 December 2017

Bernadette Cusack

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3 December 2017

Thomas F Hughes

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3 December 2017

Elizabeth H McCullough

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3 December 2017

Abdul Fauq

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3 December 2017

Peteris Romanovskis

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3 December 2017

Arno F Spatola

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3 December 2017

Terrone L Rosenberry

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3 December 2017

language of work or name

English

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publication date

8 July 2003

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Journal of Biological Chemistry

3 December 2017

published in

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3 December 2017

volume

278

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3 December 2017

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3 December 2017

page(s)

38948-38955

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Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein

3 December 2017

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Thioflavin T is a fluorescent probe of the acetylcholinesterase peripheral site that reveals conformational interactions between the peripheral and acylation sites.

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Quantitative simulation of endplate currents at neuromuscular junctions based on the reaction of acetylcholine with acetylcholine receptor and acetylcholinesterase

21 January 2018

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Replacement of the glycoinositol phospholipid anchor of Drosophila acetylcholinesterase with a transmembrane domain does not alter sorting in neurons and epithelia but results in behavioral defects

21 January 2018

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The X-ray Structure of a Transition State Analog Complex Reveals the Molecular Origins of the Catalytic Power and Substrate Specificity of Acetylcholinesterase

21 January 2018

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A powerful reactivator of alkylphosphate-inhibited acetylcholinesterase

21 January 2018

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Substrate binding to the peripheral site of acetylcholinesterase initiates enzymatic catalysis. Substrate inhibition arises as a secondary effect

21 January 2018

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Acetylthiocholine binds to asp74 at the peripheral site of human acetylcholinesterase as the first step in the catalytic pathway

21 January 2018

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Nonequilibrium Analysis Alters the Mechanistic Interpretation of Inhibition of Acetylcholinesterase by Peripheral Site Ligands

21 January 2018

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Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates

21 January 2018

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21 January 2018

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21 January 2018

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Quantitative identification of N-terminal amino acids in proteins by radiolabeled reductive methylation and amino acid analysis: application to human erythrocyte acetylcholinesterase

21 January 2018

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Acetylcholine Receptor: Covalent Attachment of Depolarizing Groups at the Active Site

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M304797200

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3 December 2017

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