Identification of chelerythrine as an inhibitor of BclXL function (Q44408527)

2 December 2017

title

Identification of chelerythrine as an inhibitor of BclXL function (English)

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2 December 2017

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2 December 2017

Kuan Onn Tan

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Victor C Yu

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Shing-Leng Chan

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2 December 2017

Mei Chin Lee

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2 December 2017

Lay-Kien Yang

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2 December 2017

Alex S Y Lee

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2 December 2017

Horst Flotow

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2 December 2017

Nai Yang Fu

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2 December 2017

Doel D Soejarto

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2 December 2017

Antony D Buss

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2 December 2017

language of work or name

English

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publication date

17 April 2003

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Journal of Biological Chemistry

2 December 2017

published in

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2 December 2017

volume

278

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2 December 2017

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2 December 2017

page(s)

20453-20456

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BCL-2 family members and the mitochondria in apoptosis

2 December 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.C300138200

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Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

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Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs

21 January 2018

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Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

21 January 2018

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Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

21 January 2018

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Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

21 January 2018

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Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening

21 January 2018

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A novel approach for characterizing protein ligand complexes: molecular basis for specificity of small-molecule Bcl-2 inhibitors

21 January 2018

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Combinatorial synthesis of natural products.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.C300138200

Chelerythrine is a potent and specific inhibitor of protein kinase C.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.C300138200

F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis

21 January 2018

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MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains

21 January 2018

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The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis

21 January 2018

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Solution structure of the antiapoptotic protein bcl-2

21 January 2018

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1-(5-Isoquinolinesulfonyl)-2-methylpiperazine induces apoptosis in human neuroblastoma cells, SH-SY5Y, through a p53-dependent pathway

21 January 2018

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Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.

21 January 2018

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

21 January 2018

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BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

21 January 2018

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

1 reference

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Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

21 January 2018

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Apoptosis: a link between cancer genetics and chemotherapy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.C300138200

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2 December 2017

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