Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles (Q44373729)

2 December 2017

title

Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles (English)

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2 December 2017

Ken Itoh

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2 December 2017

Nobunao Wakabayashi

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2 December 2017

Yasutake Katoh

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2 December 2017

Tetsuro Ishii

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2 December 2017

Tania O'Connor

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2 December 2017

Masayuki Yamamoto

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2 December 2017

publication date

1 April 2003

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2 December 2017

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2 December 2017

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2 December 2017

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2 December 2017

page(s)

379-391

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Identification of a second region upstream of the mouse heme oxygenase-1 gene that functions as a basal level and inducer-dependent transcription enhancer

2 December 2017

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Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust

21 January 2018

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Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene

21 January 2018

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High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

21 January 2018

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Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition

21 January 2018

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Degradation signals recognized by the Ubc6p-Ubc7p ubiquitin-conjugating enzyme pair

21 January 2018

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Intracellular targeting of the proteasome

21 January 2018

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Ubiquitin-dependent protein degradation

21 January 2018

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Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

21 January 2018

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Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

21 January 2018

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An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

21 January 2018

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Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins

21 January 2018

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Axis determination by inhibition of Wnt signaling in Xenopus

21 January 2018

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Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription

21 January 2018

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Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system.

21 January 2018

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Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter

21 January 2018

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Proteasome inhibitors: valuable new tools for cell biologists

21 January 2018

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Ubiquitin-mediated proteolysis of a short-lived regulatory protein depends on its cellular localization

21 January 2018

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hMAF, a small human transcription factor that heterodimerizes specifically with Nrf1 and Nrf2

21 January 2018

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The world according to Maf

21 January 2018

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Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence

21 January 2018

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Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome

21 January 2018

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The electrophile counterattack response: protection against neoplasia and toxicity.

21 January 2018

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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

21 January 2018

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Synthetic signals for ubiquitin-dependent proteolysis

21 January 2018

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Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2

21 January 2018

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Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium

21 January 2018

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A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

21 January 2018

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21 January 2018

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10.1046/J.1365-2443.2003.00640.X

21 January 2018

Identifiers

DOI

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2 December 2017

1 reference