Structure activity analysis of the pro-apoptotic, antitumor effect of nitrostyrene adducts and related compounds (Q44301839)

1 December 2017

title

Structure activity analysis of the pro-apoptotic, antitumor effect of nitrostyrene adducts and related compounds (English)

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1 December 2017

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Sylvia Kaap

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1 December 2017

Iris Quentin

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1 December 2017

Dereje Tamiru

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1 December 2017

Mohammed Shaheen

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1 December 2017

Kurt Eger

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1 December 2017

Hans Jürgen Steinfelder

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1 December 2017

language of work or name

English

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publication date

1 February 2003

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1 December 2017

published in

Biochemical Pharmacology

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1 December 2017

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1 December 2017

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1 December 2017

page(s)

603-610

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Okadaic acid, a cytotoxic polyether from two marine sponges of the genus Halichondria

1 December 2017

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Apoptosis induction by inhibitors of Ser/Thr phosphatases 1 and 2A is associated with transglutaminase activation in two different human epithelial tumour lines

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The involvement of protein phosphatases in the activation of ICE/CED-3 protease, intracellular acidification, DNA digestion, and apoptosis

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Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

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Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A.

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Characterization of natural toxins with inhibitory activity against serine/threonine protein phosphatases

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Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A

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Phase I and pharmacokinetic study of the topoisomerase II catalytic inhibitor fostriecin.

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Inhibition of protein phosphatases by Michael adducts of ascorbic acid analogues with alpha,beta-unsaturated carbonyl compounds

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A fast and sensitive technique to study the kinetics and the concentration dependencies of DNA fragmentation during drug-induced apoptosis

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Contribution of mdr1b-type P-glycoprotein to okadaic acid resistance in rat pituitary GH3 cells

7 January 2021

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7 January 2021

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Anticancer activity and protein phosphatase 1 and 2A inhibition of a new generation of cantharidin analogues

7 January 2021

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Cantharimides: a new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A.

7 January 2021

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The first two cantharidin analogues displaying PP1 selectivity

7 January 2021

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10.1016/S0006-2952(02)01618-0

7 January 2021

Identifiers

DOI

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1 December 2017

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