Immunosuppressant FK506 induces neurite outgrowth in PC12 mutant cells with impaired NGF-promoted neuritogenesis via a novel MAP kinase signaling pathway (Q44270689)

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English	Immunosuppressant FK506 induces neurite outgrowth in PC12 mutant cells with impaired NGF-promoted neuritogenesis via a novel MAP kinase signaling pathway	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 December 2017

Immunosuppressant FK506 induces neurite outgrowth in PC12 mutant cells with impaired NGF-promoted neuritogenesis via a novel MAP kinase signaling pathway (English)

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Europe PubMed Central

PubMed publication ID

1 December 2017

immunosuppression

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based on heuristic

inferred from title

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based on heuristic

inferred from title

2

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1 December 2017

author name string

Yoshio Kano

1

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1 December 2017

Toru Hasegawa

3

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1 December 2017

Rei Takahashi

4

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Europe PubMed Central

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1 December 2017

Fukumi Hiragami

5

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Europe PubMed Central

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1 December 2017

Kenji Kawamura

6

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Europe PubMed Central

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1 December 2017

Michael K Iwama

7

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Europe PubMed Central

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1 December 2017

Hirotoshi Motoda

8

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1 December 2017

Kanji Miyamoto

9

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1 December 2017

publication date

1 December 2002

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1 December 2017

Neurochemical Research

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1 December 2017

27

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1 December 2017

12

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1 December 2017

1655-1661

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1 December 2017

Mouse semaphorin H induces PC12 cell neurite outgrowth activating Ras-mitogen-activated protein kinase signaling pathway via Ca(2+) influx.

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https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

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https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerfilin I, a novel microbial metabolite inducing neurite outgrowth of PC12 cells

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https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overall lack of regulated secretion in a PC12 variant cell clone

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https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium influx induces neurite growth through a Src-Ras signaling cassette

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https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation factors, including nerve growth factor, fibroblast growth factor, and interleukin-6, induce an accumulation of an active Ras.GTP complex in rat pheochromocytoma PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor

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https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

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Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels

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https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed and sustained activation of p42/p44 mitogen-activated protein kinase induced by proteasome inhibitors through p21(ras) in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased MAP1B expression without increased phosphorylation in manganese-treated PC12Mn cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of Elk1 transcriptional activity by mitogen-activated protein kinases is negatively regulated by protein phosphatase 2B (calcineurin).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a PC12 cell sub-clone (PC12-C41) with enhanced neurite outgrowth capacity: implications for a modulatory role of high molecular weight tau in neuritogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of Neurite Outgrowth in PC12 Cells by γ-Lactam-Related Compounds via Ras-MAP Kinase Signaling Pathway Independent Mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal variants of PC12 pheochromocytoma cells with defects in cAMP-dependent protein kinases induce ornithine decarboxylase in response to nerve growth factor but not to adenosine agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras and Rap1: two highly related small GTPases with distinct function

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotransmitter release from synaptotagmin-deficient clonal variants of PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of Raf-1 and B-Raf and Ras-dependent activation of mitogen-activated protein kinase by cyclic AMP in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF-induced sustained tyrosine phosphorylation and decreased rate of down-regulation of EGF receptor in PC12h-R cells which show neuronal differentiation in response to EGF

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP and calcium ionophore induce outgrowth of neuronal processes in PC12 mutant cells in which nerve growth factor-induced outgrowth of neuronal processes is impaired

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical Role of Calcium- dependent Epidermal Growth Factor Receptor Transactivation in PC12 Cell Membrane Depolarization and Bradykinin Signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of neurite outgrowth by MAP kinase in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NGF induces transient but not sustained activation of ERK in PC12 mutant cells incapable of differentiating

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calmodulin modulates mitogen-activated protein kinase activation in response to membrane depolarization in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12515319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1021639128120

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

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