Identification of gene-selective modulators of the bile acid receptor FXR. (Q44259003)

1 December 2017

title

Identification of gene-selective modulators of the bile acid receptor FXR. (English)

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1 December 2017

Isabelle Dussault

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1 December 2017

Rick Beard

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1 December 2017

Min Lin

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1 December 2017

Kevin Hollister

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1 December 2017

Jasmine Chen

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1 December 2017

Jia-Hao Xiao

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1 December 2017

Rosh Chandraratna

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1 December 2017

Barry M Forman

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1 December 2017

language of work or name

English

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publication date

19 December 2002

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Journal of Biological Chemistry

1 December 2017

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inferred from page(s)

published in

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1 December 2017

volume

278

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1 December 2017

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1 December 2017

page(s)

7027-7033

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

1 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Review: pathogenesis of gallstones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Molecular link between cholesterol, cytokines and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

New National Cholesterol Education Program III guidelines for primary prevention lipid-lowering drug therapy: projected impact on the size, sex, and age distribution of the treatment-eligible population

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Regulation of bile acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Nuclear orphan receptors control cholesterol catabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Identification of a nuclear receptor for bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Inhibition of Estrogen Receptor Action by the Orphan Receptor SHP (Short Heterodimer Partner)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Identification of a nuclear receptor that is activated by farnesol metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Chenodeoxycholic acid: a review of its pharmacological properties and therapeutic use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Identification of a chemical tool for the orphan nuclear receptor FXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Determinants of target gene specificity for steroid/thyroid hormone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Activation of the orphan receptor RIP14 by retinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Coregulator codes of transcriptional regulation by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Activation of specific RXR heterodimers by an antagonist of RXR homodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Adenovirus-mediated transfer of a gene encoding cholesterol 7 alpha-hydroxylase into hamsters increases hepatic enzyme activity and reduces plasma total and low density lipoprotein cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Definition of the molecular and cellular mechanisms underlying the tissue-selective agonist/antagonist activities of selective estrogen receptor modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

Quality control of receptor-kinase signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

The hypolipidemic natural product guggulsterone acts as an antagonist of the bile acid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

A natural product that lowers cholesterol as an antagonist ligand for FXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

An issue of tissues: divining the split personalities of selective estrogen receptor modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209863200

21 January 2018

Identifiers

DOI

10.1074/JBC.M209863200

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1 December 2017

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