Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro (Q44183277)

30 November 2017

title

Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro (English)

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30 November 2017

Brigitte Bau

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30 November 2017

Pia M Gebhard

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30 November 2017

Jochen Haag

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30 November 2017

Thomas Knorr

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30 November 2017

Eckart Bartnik

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30 November 2017

Thomas Aigner

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30 November 2017

publication date

1 October 2002

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30 November 2017

published in

Arthritis & Rheumatology

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30 November 2017

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30 November 2017

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30 November 2017

page(s)

2648-2657

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Balance between swelling pressure and collagen tension in normal and degenerate cartilage

30 November 2017

cites work

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Preferential mRNA expression of prostromelysin relative to procollagenase and in situ localization in human articular cartilage

21 January 2018

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Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage

21 January 2018

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The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis

21 January 2018

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Development of a cleavage-site-specific monoclonal antibody for detecting metalloproteinase-derived aggrecan fragments: detection of fragments in human synovial fluids

21 January 2018

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Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints

21 January 2018

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Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage

21 January 2018

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Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent

21 January 2018

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The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

21 January 2018

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Cell-mediated catabolism of aggrecan. Evidence that cleavage at the "aggrecanase" site (Glu373-Ala374) is a primary event in proteolysis of the interglobular domain

21 January 2018

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Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins

21 January 2018

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Sites of aggrecan cleavage by recombinant human aggrecanase-1 (ADAMTS-4)

21 January 2018

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Membrane type 1 matrix metalloproteinase (MT1-MMP) cleaves the recombinant aggrecan substrate rAgg1mut at the 'aggrecanase' and the MMP sites. Characterization of MT1-MMP catabolic activities on the interglobular domain of aggrecan

21 January 2018

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ADAMTS-1 cleaves a cartilage proteoglycan, aggrecan

21 January 2018

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Effects of culture conditions and exposure to catabolic stimulators (IL-1 and retinoic acid) on the expression of matrix metalloproteinases (MMPs) and disintegrin metalloproteinases (ADAMs) by articular cartilage chondrocytes

21 January 2018

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Matrix metalloproteinases: they're not just for matrix anymore!

21 January 2018

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Isolation of RNA from small human articular cartilage specimens allows quantification of mRNA expression levels in local articular cartilage defects

21 January 2018

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Matrix metalloproteinases as therapeutic targets in arthritic diseases: bull's-eye or missing the mark?

21 January 2018

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Expression of c-fos, c-jun, jun-B, metallothionein and metalloproteinase genes in human chondrocyte

21 January 2018

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Expression and regulation of aggrecanase in arthritis: the role of TGF-beta

21 January 2018

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Gene expression (collagenase, tissue inhibitor of metalloproteinases, complement, and HLA-DR) in rheumatoid arthritis and osteoarthritis synovium. Quantitative analysis and effect of intraarticular corticosteroids

21 January 2018

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Correlation between articular cartilage collagenase activity and osteoarthritis

21 January 2018

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Severe disturbance of the distribution and expression of type VI collagen chains in osteoarthritic articular cartilage

21 January 2018

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Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules

21 January 2018

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Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2

21 January 2018

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Biochemical characterization of human collagenase-3

21 January 2018

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Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase a (MMP-2) are able to generate active enzyme

21 January 2018

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Expression of ADAMTS homologues in articular cartilage

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ART.10531

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30 November 2017

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