Eosinophil peroxidase produces hypobromous acid in the airways of stable asthmatics (Q44123354)

30 November 2017

title

Eosinophil peroxidase produces hypobromous acid in the airways of stable asthmatics (English)

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30 November 2017

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G Ian Town

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30 November 2017

Anthony J Kettle

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30 November 2017

Revathy Senthilmohan

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30 November 2017

Ruth E Aldridge

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30 November 2017

Tim Chan

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30 November 2017

Christine J van Dalen

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30 November 2017

Marti Winn

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30 November 2017

Per Venge

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30 November 2017

publication date

1 September 2002

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Free Radical Biology and Medicine

30 November 2017

published in

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30 November 2017

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30 November 2017

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30 November 2017

page(s)

847-856

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Role of eosinophil peroxidase in the origins of protein oxidation in asthma

30 November 2017

cites work

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Eosinophil peroxidase: a new serum marker of atopy and bronchial hyper-responsiveness

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Granulocyte activation markers in induced sputum: comparison between chronic obstructive pulmonary disease, asthma, and normal subjects

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Late response to allergen is associated with increased concentrations of tumor necrosis factor-alpha and IL-5 in induced sputum

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Serum eosinophil peroxidase (EPO) levels in asthmatic patients.

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The lactoperoxidase system functions in bacterial clearance of airways

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Isolation and Characterization of a Peroxidase from the Airway

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7 January 2021

Eosinophils increase lung microvascular permeability via the peroxidase-hydrogen peroxide-halide system. Bronchoconstriction and vasoconstriction unaffected by eosinophil peroxidase inhibition.

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Oxidation of protein sulfhydryls by products of peroxidase-catalyzed oxidation of thiocyanate ion

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7 January 2021

Substrates and products of eosinophil peroxidase

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Eosinophil peroxidase nitrates protein tyrosyl residues. Implications for oxidative damage by nitrating intermediates in eosinophilic inflammatory disorders

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7 January 2021

Human eosinophil peroxidase: a novel isolation procedure, spectral properties and chlorinating activity

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Determination of serum levels of dietary thiocyanate

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Selective determination of chloride and bromide ions in serum by cyclic voltammetry

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Thiocyanate and chloride as competing substrates for myeloperoxidase.

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Production of brominating intermediates by myeloperoxidase. A transhalogenation pathway for generating mutagenic nucleobases during inflammation

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Chlorination of tyrosyl residues in peptides by myeloperoxidase and human neutrophils

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7 January 2021

3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima

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7 January 2021

Reactions of hypochlorous acid with tyrosine and peptidyl-tyrosyl residues give dichlorinated and aldehydic products in addition to 3-chlorotyrosine

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7 January 2021

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7 January 2021

3-Bromotyrosine and 3,5-dibromotyrosine are major products of protein oxidation by eosinophil peroxidase: potential markers for eosinophil-dependent tissue injury in vivo

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7 January 2021

Eosinophils generate brominating oxidants in allergen-induced asthma

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7 January 2021

Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species

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7 January 2021

Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis

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7 January 2021

Non-invasive assessment of bronchial inflammation in asthma: no correlation between eosinophilia of induced sputum and bronchial responsiveness to inhaled hypertonic saline

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7 January 2021

Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects

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7 January 2021

Assay of the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase

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7 January 2021

Superoxide modulates the activity of myeloperoxidase and optimizes the production of hypochlorous acid

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7 January 2021

Protein Carbonyl Measurement by a Sensitive ELISA Method

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7 January 2021

Leukocyte myeloperoxidase and salivary lactoperoxidase: identification and quantitation in human mixed saliva

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7 January 2021

Biomarkers of myeloperoxidase-derived hypochlorous acid

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7 January 2021

On the irreversible destruction of reduced nicotinamide nucleotides by hypohalous acids

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7 January 2021

Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients

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7 January 2021

Altered lung antioxidant status in patients with mild asthma

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7 January 2021

Endogenous airway acidification. Implications for asthma pathophysiology

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7 January 2021

Endogenous airway acidification: implications for asthma pathology

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7 January 2021

Role of the eosinophil in protein oxidation in asthma: possible effects on proteinase/antiproteinase balance

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7 January 2021

Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to oxidize alpha-amino acids to a family of reactive aldehydes. Mechanistic studies identifying labile intermediates along the reaction pathway

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7 January 2021

Myeloperoxidase inactivation in the course of catalysis of chlorination of taurine

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7 January 2021

Secretion and inactivation of myeloperoxidase by isolated neutrophils

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7 January 2021

10.1016/S0891-5849(02)00976-0

Identifiers

DOI

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30 November 2017

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