The protein synthesis inhibitors, oxazolidinones and chloramphenicol, cause extensive translational inaccuracy in vivo (Q44129163)

30 November 2017

title

The protein synthesis inhibitors, oxazolidinones and chloramphenicol, cause extensive translational inaccuracy in vivo (English)

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30 November 2017

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ChEBI release 2020-05-28

Jill Thompson

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30 November 2017

Michael O'Connor

series ordinal

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30 November 2017

Jonathan A Mills

series ordinal

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30 November 2017

Albert E Dahlberg

series ordinal

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30 November 2017

language of work or name

English

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publication date

1 September 2002

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Journal of Molecular Biology

30 November 2017

published in

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30 November 2017

volume

322

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30 November 2017

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30 November 2017

page(s)

273-279

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Oxazolidinones, a new class of synthetic antibacterial agents: in vitro and in vivo activities of DuP 105 and DuP 721

30 November 2017

cites work

1 reference

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Resistance mutations in 23 S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center

7 January 2021

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Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action.

7 January 2021

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Resistance to linezolid: characterization of mutations in rRNA and comparison of their occurrences in vancomycin-resistant enterococci

7 January 2021

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1H nuclear magnetic resonance study of oxazolidinone binding to bacterial ribosomes.

7 January 2021

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Mechanism of action of DuP 721: inhibition of an early event during initiation of protein synthesis

7 January 2021

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Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions

7 January 2021

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On the target of a novel class of antibiotics, oxazolidinones, active against multidrug-resistant Gram-positive bacteria.

7 January 2021

1 reference

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The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria

7 January 2021

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Functional interactions within 23S rRNA involving the peptidyltransferase center.

7 January 2021

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Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

7 January 2021

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A ribosomal ambiguity mutation in the 530 loop of E. coli 16S rRNA.

7 January 2021

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rRNA-mRNA base pairing stimulates a programmed -1 ribosomal frameshift

7 January 2021

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Mutagenesis of the peptidyltransferase center of 23S rRNA: the invariant U2449 is dispensable

7 January 2021

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Recognition of cognate transfer RNA by the 30S ribosomal subunit

7 January 2021

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Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit

7 January 2021

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Ribosomal RNA is the target for oxazolidinones, a novel class of translational inhibitors

7 January 2021

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Mutation of a highly conserved base in the yeast mitochondrial 21S rRNA restricts ribosomal frameshifting.

7 January 2021

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Genetic probes of ribosomal RNA function

7 January 2021

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The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

7 January 2021

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Translating old drugs into new treatments: ribosomal frameshifting as a target for antiviral agents

7 January 2021

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Aminoglycoside suppression at UAG, UAA and UGA codons in Escherichia coli and human tissue culture cells

7 January 2021

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Recent advances in peptide chain termination

7 January 2021

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Slippery runs, shifty stops, backward steps, and forward hops: -2, -1, +1, +2, +5, and +6 ribosomal frameshifting

7 January 2021

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An Escherichia coli strain with all chromosomal rRNA operons inactivated: complete exchange of rRNA genes between bacteria

7 January 2021

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Gene organization and primary structure of a ribosomal RNA operon from Escherichia coli

7 January 2021

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Antibiotic resistance mutations in ribosomal RNA genes of Escherichia coli.

7 January 2021

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Deficiency of 1-methylguanosine in tRNA from Salmonella typhimurium induces frameshifting by quadruplet translocation

7 January 2021

1 reference

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The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin

7 January 2021

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Phenotypic Suppression in Escherichia coli by Chloramphenicol and Other Reversible Inhibitors of the Ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900784-2

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0022-2836(02)00784-2

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30 November 2017

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