Oxidation of methoxyphenethylamines by cytochrome P450 2D6. Analysis of rate-limiting steps. (Q44047581)

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10 November 2019

title

Oxidation of methoxyphenethylamines by cytochrome P450 2D6. Analysis of rate-limiting steps (English)

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10 November 2019

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10 November 2019

F Peter Guengerich

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10 November 2019

Imad H Hanna

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10 November 2019

Hideaki Sato

series ordinal

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10 November 2019

Martha V Martin

series ordinal

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10 November 2019

language of work or name

English

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publication date

1 July 2002

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Journal of Biological Chemistry

10 November 2019

published in

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10 November 2019

volume

277

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10 November 2019

issue

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10 November 2019

page(s)

33711-33719

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Steady-state analysis of kinetic isotope effects in enzymic reactions

10 November 2019

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Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation

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Oxidation of substituted N,N-dimethylanilines by cytochrome P-450: estimation of the effective oxidation-reduction potential of cytochrome P-450.

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Oxidations of p-alkoxyacylanilides catalyzed by human cytochrome P450 1A2: structure-activity relationships and simulation of rate constants of individual steps in catalysis.

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Diversity in mechanisms of substrate oxidation by cytochrome P450 2D6. Lack of an allosteric role of NADPH-cytochrome P450 reductase in catalytic regioselectivity

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Oxidation of phenethylamine derivatives by cytochrome P450 2D6: the issue of substrate protonation in binding and catalysis

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Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

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Influence of amino acid residue 374 of cytochrome P-450 2D6 (CYP2D6) on the regio- and enantio-selective metabolism of metoprolol

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21 January 2018

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21 January 2018

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21 January 2018

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A model for human cytochrome P450 2D6 based on homology modeling and NMR studies of substrate binding

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21 January 2018

Identifiers

DOI

10.1074/JBC.M205146200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093814%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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