Induction of Epstein-Barr virus kinases to sensitize tumor cells to nucleoside analogues (Q33982537)

30 July 2017

title

Induction of Epstein-Barr virus kinases to sensitize tumor cells to nucleoside analogues (English)

1 reference

30 July 2017

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S M Moore

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30 July 2017

J S Cannon

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30 July 2017

Y C Tanhehco

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30 July 2017

F M Hamzeh

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30 July 2017

R F Ambinder

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30 July 2017

language of work or name

English

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publication date

1 July 2001

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Antimicrobial Agents and Chemotherapy

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

2082-2091

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Human herpesvirus 8 open reading frame 21 is a thymidine and thymidylate kinase of narrow substrate specificity that efficiently phosphorylates zidovudine but not ganciclovir

30 July 2017

cites work

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28 July 2018

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Human herpesvirus 8-encoded thymidine kinase and phosphotransferase homologues confer sensitivity to ganciclovir

28 July 2018

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The U69 gene of human herpesvirus 6 encodes a protein kinase which can confer ganciclovir sensitivity to baculoviruses

28 July 2018

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The Epstein-Barr virus thymidine kinase does not phosphorylate ganciclovir or acyclovir and demonstrates a narrow substrate specificity compared to the herpes simplex virus type 1 thymidine kinase

28 July 2018

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Arginine butyrate-induced susceptibility to ganciclovir in an Epstein-Barr-virus-associated lymphoma

28 July 2018

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Phosphorylation and cytotoxicity of therapeutic nucleoside analogues: a comparison of alpha and gamma herpesvirus thymidine kinase suicide genes.

28 July 2018

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The Epstein-Barr virus genome encodes deoxythymidine kinase activity in a nested internal open reading frame

28 July 2018

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The human cytomegalovirus UL97 protein is a protein kinase that autophosphorylates on serines and threonines.

28 July 2018

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CpG methylation of the major Epstein-Barr virus latency promoter in Burkitt's lymphoma and Hodgkin's disease

28 July 2018

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28 July 2018

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Regulation of Epstein-Barr virus BamHI-H divergent promoter by DNA methylation

28 July 2018

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Substrate specificity of Epstein-Barr virus thymidine kinase

28 July 2018

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28 July 2018

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Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation

28 July 2018

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

28 July 2018

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The biochemistry and mechanism of action of acyclovir

28 July 2018

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Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex

28 July 2018

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Activation of the epstein-barr virus genome by 5-aza-cytidine in latently infected human lymphoid lines

28 July 2018

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Intracellular metabolism and enzymatic phosphorylation of 9-(1,3-dihydroxy-2-propoxymethyl)guanine and acyclovir in herpes simplex virus-infected and uninfected cells

28 July 2018

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Analysis of spontaneous mutations in a chromosomally located HSV-1 thymidine kinase (TK) gene in a human cell line

28 July 2018

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Identification of an Epstein-Barr virus-coded thymidine kinase

28 July 2018

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Evidence that the 'active centre' of the herpes simplex virus thymidine kinase involves an interaction between three distinct regions of the polypeptide

28 July 2018

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Activity of 9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine in the treatment of cytomegalovirus pneumonia

28 July 2018

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Inhibition of cellular DNA polymerase alpha and human cytomegalovirus-induced DNA polymerase by the triphosphates of 9-(2-hydroxyethoxymethyl)guanine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine

28 July 2018

1 reference

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Constitutive expression in human cells of herpes simplex virus type 1 glycoprotein B gene cloned in an episomal eukaryotic vector.

28 July 2018

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Characterization of the Epstein-Barr virus-encoded thymidine kinase expressed in heterologous eucaryotic and procaryotic systems

28 July 2018

1 reference

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Plasmid DNA mediated transfer of the herpes simplex virus thymidine kinase gene to a new bromodeoxyuridine resistant variant of human primary lung carcinoma cells

28 July 2018

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Herpes simplex virus type 1 and human DNA polymerase interactions with 2'-deoxyguanosine 5'-triphosphate analogues. Kinetics of incorporation into DNA and induction of inhibition

28 July 2018

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Identification of new protein kinase-related genes in three herpesviruses, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus

28 July 2018

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The role of methylation in the phenotype-dependent modulation of Epstein-Barr nuclear antigen 2 and latent membrane protein genes in cells latently infected with Epstein-Barr virus

28 July 2018

1 reference

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5-Azacytidine up regulates the expression of Epstein-Barr virus nuclear antigen 2 (EBNA-2) through EBNA-6 and latent membrane protein in the Burkitt's lymphoma line rael

28 July 2018

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Detection of EBV gene expression in Reed-Sternberg cells of Hodgkin's disease

28 July 2018

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Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections

28 July 2018

1 reference

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Evaluation of continuous infusion low-dose 5-azacytidine in the treatment of myelodysplastic syndromes

28 July 2018

1 reference

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Epstein-Barr virus in AIDS-related primary central nervous system lymphoma

28 July 2018

1 reference

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A system for assaying homologous recombination at the endogenous human thymidine kinase gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Intracellular zidovudine (ZDV) and ZDV phosphates as measured by a validated combined high-pressure liquid chromatography-radioimmunoassay procedure

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Methylation of discrete sites within the enhancer region regulates the activity of the Epstein-Barr virus BamHI W promoter in Burkitt lymphoma lines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Cloning and expression of a cDNA encoding the Epstein-Barr virus thymidine kinase gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Induction of the Epstein-Barr virus (EBV) cycle in latently infected cells by n-butyrate

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Persisting oncogenic herpesvirus induced by the tumour promoter TPA

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

A protein kinase activity associated with Epstein-Barr virus BGLF4 phosphorylates the viral early antigen EA-D in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Analysis of methylation patterns in the regulatory region of the latent Epstein-Barr virus promoter BCR2 by automated fluorescent genomic sequencing

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Epstein-Barr virus (EBV) in endemic Burkitt's lymphoma: molecular analysis of primary tumor tissue

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

BCL-2 but not its Epstein-Barr virus-encoded homologue, BHRF1, is commonly expressed in posttransplantation lymphoproliferative disorders.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Gene therapy for the treatment of malignant brain tumors with in vivo tumor transduction with the herpes simplex thymidine kinase gene/ganciclovir system

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Epstein-Barr virus is localized in the tumour cells of nasal lymphomas of NK, T or B cell type.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Transcriptional activation of the Epstein-Barr virus latency C promoter after 5-azacytidine treatment: evidence that demethylation at a single CpG site is crucial.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Cross-linking of cell surface immunoglobulins induces Epstein-Barr virus in Burkitt lymphoma lines

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90604

Detection of Epstein-Barr viral genomes in Reed-Sternberg cells of Hodgkin's disease

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11408227

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Brief report: treatment with azacitidine of patients with end-stage beta-thalassemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11408227

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.45.7.2082-2091.2001

1 reference

30 July 2017

1 reference

30 July 2017

1 reference