Neuroprotective efficacy of repinotan HCl, a 5-HT1A receptor agonist, in animal models of stroke and traumatic brain injury (Q33984607)

30 July 2017

title

Neuroprotective efficacy of repinotan HCl, a 5-HT1A receptor agonist, in animal models of stroke and traumatic brain injury (English)

1 reference

30 July 2017

main subject

traumatic brain injury

0 references

author name string

Frank Mauler

series ordinal

1 reference

30 July 2017

Ervin Horváth

series ordinal

1 reference

30 July 2017

publication date

1 April 2005

1 reference

Journal of Cerebral Blood Flow & Metabolism

30 July 2017

published in

1 reference

30 July 2017

1 reference

30 July 2017

1 reference

30 July 2017

page(s)

451-459

1 reference

The G protein-coupled 5-HT1A receptor causes suppression of caspase-3 through MAPK and protein kinase Calpha

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

The 5-HT1A receptor agonist Bay x 3702 inhibits apoptosis induced by serum deprivation in cultured neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

The neuroprotective effect of a new serotonin receptor agonist, BAY X3702, upon focal ischemic brain damage caused by acute subdural hematoma in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Changes in extracellular concentrations of glutamate, aspartate, glycine, dopamine, serotonin, and dopamine metabolites after transient global ischemia in the rabbit brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Clinical trials with neuroprotective drugs in acute ischaemic stroke: are we doing the right thing?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Neuroprotective action of tacrolimus (FK506) in focal and global cerebral ischemia in rodents: dose dependency, therapeutic time window and long-term efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Oral post-lesion administration of 5-HT(1A) receptor agonist repinotan hydrochloride (BAY x 3702) attenuates NMDA-induced delayed neuronal death in rat magnocellular nucleus basalis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Intracerebral inflammatory response to experimental brain contusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Relationship between the neuroprotective effect of Na+/H+ exchanger inhibitor SM-20220 and the timing of its administration in a transient middle cerebral artery occlusion model of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

The selective 5-HT(1A) receptor agonist repinotan HCl attenuates histopathology and spatial learning deficits following traumatic brain injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Psychotogenicity and N-methyl-D-aspartate receptor antagonism: implications for neuroprotective pharmacotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Effect of 5-hydroxytryptamine 1A receptor agonist BAY X 3702 on BCL-2 and BAX proteins level in the ipsilateral cerebral cortex of rats after transient focal ischaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Cerestat and other NMDA antagonists in ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Mechanisms, challenges and opportunities in stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Regulation of glutamate release via NMDA and 5-HT1A receptors in guinea pig dentate gyrus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Inhibition of evoked glutamate release by the neuroprotective 5-HT(1A) receptor agonist BAY x 3702 in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Neuroprotective and brain edema-reducing efficacy of the novel cannabinoid receptor agonist BAY 38-7271

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Characterization of the diarylether sulfonylester (-)-(R)-3-(2-hydroxymethylindanyl-4-oxy)phenyl-4,4,4-trifluoro-1-sulfonate (BAY 38-7271) as a potent cannabinoid receptor agonist with neuroprotective properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Type and extent of hemispheric brain infarctions and clinical outcome in early and delayed middle cerebral artery recanalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Glutamate and the pathophysiology of hypoxic--ischemic brain damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Neuroprotective effect of 5-HT1A receptor agonist, Bay X 3702, demonstrated in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Relationship between extracellular neurotransmitter amino acids and energy metabolism during cerebral ischemia in rats monitored by microdialysis and in vivo magnetic resonance spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

The 5-HT1A receptor agonist BAY x 3702 prevents staurosporine-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

Changes in amino acid neurotransmitters and cerebral blood flow in the ischemic penumbral region following middle cerebral artery occlusion in the rat: correlation with histopathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

ZK200775: a phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

S-100beta protects cultured neurons against glutamate- and staurosporine-induced damage and is involved in the antiapoptotic action of the 5 HT(1A)-receptor agonist, Bay x 3702

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

7 January 2021

In vivo actions of the selective 5-HT1A receptor agonist BAY x 3702 on serotonergic cell firing and release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

7 January 2021

BAY 38-7271: a novel highly selective and highly potent cannabinoid receptor agonist for the treatment of traumatic brain injury.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

7 January 2021

Blockade of voltage-sensitive Na(+) channels by the 5-HT(1A) receptor agonist 8-OH-DPAT: possible significance for neuroprotection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

7 January 2021

Stimulation of 5-HT(1A) receptors reduces apoptosis after transient forebrain ischemia in the rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

7 January 2021

Extracellular glutamate during focal cerebral ischaemia in rats: time course and calcium dependency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600038

7 January 2021

Identifiers

DOI

10.1038/SJ.JCBFM.9600038

1 reference

30 July 2017

1 reference