Properties of NACP/alpha-synuclein and its role in Alzheimer's disease (Q33971315)

30 July 2017

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title

Properties of NACP/alpha-synuclein and its role in Alzheimer's disease (English)

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30 July 2017

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A Iwai

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30 July 2017

language of work or name

English

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publication date

1 July 2000

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Biochimica et Biophysica Acta

30 July 2017

published in

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30 July 2017

volume

1502

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30 July 2017

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30 July 2017

page(s)

95-109

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Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

The rat brain synucleins; family of proteins transiently associated with neuronal membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Identification of two distinct synucleins from human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Purification and characterization of a novel brain-specific 14-kDa protein

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Persyn, a member of the synuclein family, has a distinct pattern of expression in the developing nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Peripheral Nervous System-specific Genes Identified by Subtractive cDNA Cloning

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Synoretin--A new protein belonging to the synuclein family

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Genetic studies in Alzheimer's disease with an NACP/alpha-synuclein polymorphism

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

High-resolution mapping of SNCA encoding α-synuclein, the non-Aβ component of Alzheimer’s disease amyloid precursor, to human chromosome 4q21.3→q22 by fluorescence in situ hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

The human NACP/α-synuclein gene: chromosome assignment to 4q21.3–q22 and TaqI RFLP analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Assignment of human alpha-synuclein (SNCA) and beta-synuclein (SNCB) genes to chromosomes 4q21 and 5q35.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Patterns of aberrant sprouting in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Localization of phosphoneuroprotein 14 (PNP 14) and its mRNA expression in rat brain determined by immunocytochemistry and in situ hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Delayed localization of synelfin (synuclein, NACP) to presynaptic terminals in cultured rat hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Synelfin regulation during the critical period for song learning in normal and isolated juvenile zebra finches

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

A variety of cerebral amyloid deposits in the brains of the Alzheimer-type dementia demonstrated by beta protein immunostaining

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Alzheimer's disease: the amyloid cascade hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Synaptic loss in Alzheimer's disease and other dementias

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Regional synaptic pathology in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Synaptic pathology in Alzheimer's disease: immunological data for markers of synaptic and large dense-core vesicles.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Neuritic pathology and dementia in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Correlations of synaptic and pathological markers with cognition of the elderly

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Neuropathological stageing of Alzheimer-related changes

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Loss of synaptophysin-like immunoreactivity in the hippocampal formation is an early phenomenon in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

The role of synaptic proteins in the pathogenesis of disorders of the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Physiological production of the beta-amyloid protein and the mechanism of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Morphological, Biochemical, and Genetic Support for an Apolipoprotein E Effect on Microtubular Metabolisma

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Light and electron microscopic localization of presenilin-1 in primate brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Alpha-synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease beta-amyloid plaque cores.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Characterization of the precursor protein of the non-A beta component of senile plaques (NACP) in the human central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Non-A.beta. Component of Alzheimer's Disease Amyloid (NAC) is Amyloidogenic

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

The core Alzheimer's peptide NAC forms amyloid fibrils which seed and are seeded by beta-amyloid: is NAC a common trigger or target in neurodegenerative disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Residues in the synuclein consensus motif of the α-synuclein fragment, NAC, participate in transglutaminase-catalysed cross-linking to Alzheimer-disease amyloid βA4 peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

The synaptic protein NACP is abnormally expressed during the progression of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Failure to replicate a protective effect of allele 2 of NACP/alpha-synuclein polymorphism in Alzheimer's disease: an association study

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

α-Synuclein in Lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Human recombinant NACP/alpha-synuclein is aggregated and fibrillated in vitro: relevance for Lewy body disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Synthetic filaments assembled from C-terminally truncated alpha-synuclein

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Cholesterol-dependent generation of a unique amyloid beta-protein from apically missorted amyloid precursor protein in MDCK cells

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Changes in presynaptic protein NACP/alpha-synuclein in an ischemic gerbil hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Amyloid beta-protein (A beta) associated with lipid molecules: immunoreactivity distinct from that of soluble A beta.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

A detergent-insoluble membrane compartment contains A beta in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

The Presence of Amyloid β-Protein in the Detergent-Insoluble Membrane Compartment of Human Neuroblastoma Cells†

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Characterization of the interactions of Alzheimer beta-amyloid peptides with phospholipid membranes.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900036-3

7 January 2021

10.1016/S0925-4439(00)00036-3

Identifiers

DOI

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30 July 2017

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