Insulin like growth factor-I: a critical mediator of the skeletal response to parathyroid hormone (Q33970422)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21787292%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

review article

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title

Insulin like growth factor-I: a critical mediator of the skeletal response to parathyroid hormone (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21787292%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

Daniel D Bikle

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21787292%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Yongmei Wang

series ordinal

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8 February 2020

publication date

1 June 2012

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21787292%20AND%20SRC:MED&resulttype=core&format=json

Current molecular pharmacology

8 February 2020

published in

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8 February 2020

volume

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8 February 2020

issue

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8 February 2020

page(s)

135-142

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EphrinB2 regulation by PTH and PTHrP revealed by molecular profiling in differentiating osteoblasts

8 February 2020

cites work

1 reference

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Studies on the mechanisms of the skeletal anabolic action of endogenous and exogenous parathyroid hormone

5 July 2018

1 reference

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PTH/cAMP/PKA signaling facilitates canonical Wnt signaling via inactivation of glycogen synthase kinase-3beta in osteoblastic Saos-2 cells

5 July 2018

1 reference

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Effects of insulin-like growth factor binding proteins in bone -- a matter of cell and site

5 July 2018

1 reference

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Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion

5 July 2018

1 reference

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Molecular and cellular mechanisms of the anabolic effect of intermittent PTH

5 July 2018

1 reference

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Overexpression of the transcriptional factor Runx2 in osteoblasts abolishes the anabolic effect of parathyroid hormone in vivo

5 July 2018

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Contributions of parathyroid hormone (PTH)/PTH-related peptide receptor signaling pathways to the anabolic effect of PTH on bone

5 July 2018

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PTH stimulates bone formation in mice deficient in Lrp5

5 July 2018

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Pregnancy-associated plasma protein-A increases osteoblast proliferation in vitro and bone formation in vivo

5 July 2018

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The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment

5 July 2018

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Effects of parathyroid hormone on Wnt signaling pathway in bone

5 July 2018

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Activation of the insulin-like growth factor binding protein-5 promoter by parathyroid hormone in osteosarcoma cells requires activation of an activated protein-2 element

5 July 2018

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SOST is a target gene for PTH in bone

5 July 2018

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Insulin-like growth factor-binding protein-5 induces a gender-related decrease in bone mineral density in transgenic mice

5 July 2018

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Skeletal hormones and the C/EBP and Runx transcription factors: interactions that integrate and redefine gene expression

5 July 2018

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Genetic strategies for elucidating insulin-like growth factor action in bone

5 July 2018

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Paracrine Overexpression of IGFBP‐4 in Osteoblasts of Transgenic Mice Decreases Bone Turnover and Causes Global Growth Retardation

5 July 2018

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Insulin-like growth factor (IGF)-I gene deletion

5 July 2018

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Circulating levels of IGF-1 directly regulate bone growth and density

5 July 2018

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IGF-I regulates osteoprotegerin (OPG) and receptor activator of nuclear factor-kappaB ligand in vitro and OPG in vivo.

5 July 2018

1 reference

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Parathyroid hormone is essential for normal fetal bone formation

5 July 2018

1 reference

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Parathyroid hormone-dependent signaling pathways regulating genes in bone cells.

5 July 2018

1 reference

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Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis

5 July 2018

1 reference

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The somatomedin hypothesis: 2001.

5 July 2018

1 reference

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Normal growth and development in the absence of hepatic insulin-like growth factor I

5 July 2018

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Insulin-like growth factor system abnormalities in hepatitis C-associated osteosclerosis. Potential insights into increasing bone mass in adults

5 July 2018

1 reference

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The Mitogenic Effect of Parathyroid Hormone Is Associated with E2F-Dependent Activation of Cyclin-Dependent Kinase 1 (cdc2) in Osteoblast Precursors

5 July 2018

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Regional responsiveness of the tibia to intermittent administration of parathyroid hormone as affected by skeletal unloading.

5 July 2018

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Characterization and function of the receptor for IGF-I in human preosteoclastic cells

5 July 2018

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The insulin-like growth factor system and the coupling of formation to resorption

5 July 2018

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Role of insulin-like growth factors in embryonic and postnatal growth

5 July 2018

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Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

5 July 2018

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Anabolic actions of parathyroid hormone on bone

5 July 2018

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Osteoblasts mediate insulin-like growth factor-I and -II stimulation of osteoclast formation and function

5 July 2018

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Parathyroid hormone increases the concentration of insulin-like growth factor-I and transforming growth factor beta 1 in rat bone

5 July 2018

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Studies on the mechanisms by which insulin-like growth factor (IGF) binding protein-4 (IGFBP-4) and IGFBP-5 modulate IGF actions in bone cells

5 July 2018

1 reference

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Molecular and cellular aspects of the insulin-like growth factor I receptor

5 July 2018

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Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures

5 July 2018

1 reference

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Parathyroid hormone stimulates release of insulin-like growth factor-I (IGF-I) and IGF-II from neonatal mouse calvaria in organ culture

5 July 2018

1 reference

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Parathyroid hormone induces c-fos and c-jun messenger RNA in rat osteoblastic cells

5 July 2018

1 reference

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IGF-I receptor is required for the anabolic actions of parathyroid hormone on bone

5 July 2018

1 reference

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Effects of transient PTH on early proliferation, apoptosis, and subsequent differentiation of osteoblast in primary osteoblast cultures

29 October 2018

1 reference

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Role of IGF-I signaling in regulating osteoclastogenesis

29 October 2018

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Gender differences in the response of CD-1 mouse bone to parathyroid hormone: potential role of IGF-I.

29 October 2018

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Cells of the osteoclast lineage as mediators of the anabolic actions of parathyroid hormone in bone

29 October 2018

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Comparison of the action of transient and continuous PTH on primary osteoblast cultures expressing differentiation stage-specific GFP.

29 October 2018

1 reference

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PTH differentially regulates expression of RANKL and OPG.

29 October 2018

1 reference

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Potentiating role of IGFBP-2 on IGF-II-stimulated alkaline phosphatase activity in differentiating osteoblasts

29 October 2018

1 reference

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Perturbations in Bone Formation and Resorption in Insulin-Like Growth Factor Binding Protein-3 Transgenic Mice

29 October 2018

1 reference

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Effects of an excess and a deficiency of endogenous parathyroid hormone on volumetric bone mineral density and bone geometry determined by peripheral quantitative computed tomography in female subjects.

29 October 2018

1 reference

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The Effects of Parathyroid Hormone, Alendronate, or Both in Men with Osteoporosis

29 October 2018

1 reference

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The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis

29 October 2018

1 reference

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Mediators of the biphasic responses of bone to intermittent and continuously administered parathyroid hormone

29 October 2018

1 reference

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Insulin-like growth factor-binding protein-2 (IGFBP-2) overexpression negatively regulates bone size and mass, but not density, in the absence and presence of growth hormone/IGF-I excess in transgenic mice

29 October 2018

1 reference

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Insulin-like growth factor I is required for the anabolic actions of parathyroid hormone on mouse bone

29 October 2018

1 reference

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Anabolic action of parathyroid hormone is skeletal site specific at the tissue and cellular levels in mice.

29 October 2018

1 reference

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The skeletal structure of insulin-like growth factor I-deficient mice

29 October 2018

1 reference

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Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: correlation with osteoclast-like cell formation

29 October 2018

1 reference

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Skeletal unloading causes resistance of osteoprogenitor cells to parathyroid hormone and to insulin-like growth factor-I.

29 October 2018

1 reference

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Regional variation of insulin-like growth factor-I gene expression in mature rat bone and cartilage.

29 October 2018

1 reference

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Treatment of ovariectomized rats with the complex of rhIGF-I/IGFBP-3 increases cortical and cancellous bone mass and improves structure in the femoral neck

29 October 2018

1 reference

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Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis

29 October 2018

1 reference

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Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation

29 October 2018

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12 December 2020

IGF-binding protein-5 stimulates osteoblast activity and bone accretion in ovariectomized mice

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12 December 2020

Catabolic effects of continuous human PTH (1--38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation

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12 December 2020

Effects of daily treatment with parathyroid hormone on bone microarchitecture and turnover in patients with osteoporosis: a paired biopsy study

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12 December 2020

Transgenic mice overexpressing insulin-like growth factor binding protein-5 display transiently decreased osteoblastic function and osteopenia

1 reference

12 December 2020

Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization

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12 December 2020

Effects of Intermittent Parathyroid Hormone Administration on Bone Mineralization Density in Iliac Crest Biopsies from Patients with Osteoporosis: A Paired Study before and after Treatment

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12 December 2020

Anabolic and catabolic bone effects of human parathyroid hormone (1-34) are predicted by duration of hormone exposure

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12 December 2020

Skeletal abnormalities in Pth-null mice are influenced by dietary calcium

1 reference

12 December 2020

In vivo distribution of parathyroid hormone receptors in bone: evidence that a predominant osseous target cell is not the mature osteoblast

1 reference

12 December 2020

Transforming growth factor-beta stimulates bone matrix apposition and bone cell replication in cultured fetal rat calvariae

1 reference

12 December 2020

Parathyroid hormone induces sequential c-fos expression in bone cells in vivo: in situ localization of its receptor and c-fos messenger ribonucleic acids

1 reference

12 December 2020

Growth hormone replacement is important for the restoration of parathyroid hormone sensitivity and improvement in bone metabolism in older adult growth hormone-deficient patients

1 reference

12 December 2020

Co-treatment of PTH with osteoprotegerin or alendronate increases its anabolic effect on the skeleton of oophorectomized mice

1 reference

12 December 2020

Increased bone formation by intermittent parathyroid hormone administration is due to the stimulation of proliferation and differentiation of osteoprogenitor cells in bone marrow

1 reference

12 December 2020

Parathyroid hormone restores bone mass and enhances osteoblast insulin-like growth factor I gene expression in ovariectomized rats

1 reference

12 December 2020

In vivo, human parathyroid hormone fragment (hPTH 1-34) transiently stimulates immediate early response gene expression, but not proliferation, in trabecular bone cells of young rats

1 reference

12 December 2020

Identification and characterization of the insulin-like growth factor I receptor in mature rabbit osteoclasts

1 reference

12 December 2020

Normal human osteoclasts formed from peripheral blood monocytes express PTH type 1 receptors and are stimulated by PTH in the absence of osteoblasts

1 reference

12 December 2020

Anabolic Actions of Parathyroid Hormone on Bone*

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12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21787292%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

21787292

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21787292%20AND%20SRC:MED&resulttype=core&format=json