Differential modulation of androgen receptor-mediated transactivation by Smad3 and tumor suppressor Smad4. (Q33961300)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12226080%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

title

Differential modulation of androgen receptor-mediated transactivation by Smad3 and tumor suppressor Smad4 (English)

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13 November 2019

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13 November 2019

Ko-En Huang

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13 November 2019

Shiuh Young Chang

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13 November 2019

Wen-Lung Ma

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13 November 2019

Wen-Jye Lin

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13 November 2019

Chawnshang Chang

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13 November 2019

language of work or name

English

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publication date

10 September 2002

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Journal of Biological Chemistry

13 November 2019

published in

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13 November 2019

volume

277

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13 November 2019

issue

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13 November 2019

page(s)

43749-43756

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Smads: transcriptional activators of TGF-beta responses

13 November 2019

cites work

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TGF-beta signal transduction

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Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

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MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

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TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

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A human Mad protein acting as a BMP-regulated transcriptional activator

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Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily

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The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

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Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

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Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

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The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

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G1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: phenotypes reversed by a tumorigenic mutation

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Comparative mutational analysis of DPC4 (Smad4) in prostatic and colorectal carcinomas

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Molecular Cloning of Human and Rat Complementary DNA Encoding Androgen Receptors

21 January 2018

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Isolation and characterization of ARA160 as the first androgen receptor N-terminal-associated coactivator in human prostate cells

21 January 2018

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Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor

21 January 2018

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Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate

21 January 2018

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Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells

21 January 2018

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The linkage of Kennedy's neuron disease to ARA24, the first identified androgen receptor polyglutamine region-associated coactivator

21 January 2018

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Retinoblastoma, a tumor suppressor, is a coactivator for the androgen receptor in human prostate cancer DU145 cells.

21 January 2018

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Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells

21 January 2018

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From androgen receptor to the general transcription factor TFIIH. Identification of cdk activating kinase (CAK) as an androgen receptor NH(2)-terminal associated coactivator

21 January 2018

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Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells

21 January 2018

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From transforming growth factor-beta signaling to androgen action: identification of Smad3 as an androgen receptor coregulator in prostate cancer cells

21 January 2018

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Cross-talk between transforming growth factor-beta and estrogen receptor signaling through Smad3.

21 January 2018

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Cross-talk between 1,25-dihydroxyvitamin D3 and transforming growth factor-beta signaling requires binding of VDR and Smad3 proteins to their cognate DNA recognition elements

21 January 2018

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Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

21 January 2018

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The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation

21 January 2018

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21 January 2018

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Characterization of functional domains within Smad4/DPC4

21 January 2018

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p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation

21 January 2018

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Inhibition of histone deacetylation augments dihydrotestosterone induction of androgen receptor levels: an explanation for trichostatin A effects on androgen-induced chromatin remodeling and transcription of the mouse mammary tumor virus promoter.

21 January 2018

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5'TG3' interacting factor interacts with Sin3A and represses AR-mediated transcription

21 January 2018

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Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcription

21 January 2018

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An essential role for Mad homology domain 1 in the association of Smad3 with histone deacetylase activity*.

21 January 2018

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Ski acts as a co-repressor with Smad2 and Smad3 to regulate the response to type beta transforming growth factor

21 January 2018

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Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer

21 January 2018

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A Smad transcriptional corepressor

21 January 2018

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Glucocorticoid receptor inhibits transforming growth factor-beta signaling by directly targeting the transcriptional activation function of Smad3

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21 January 2018

Identifiers

DOI

10.1074/JBC.M205603200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12226080%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

1 reference

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