Role of the IkappaB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat liver epithelial cells (Q33964689)

30 July 2017

title

Role of the IkappaB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat liver epithelial cells (English)

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30 July 2017

M Arsura

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30 July 2017

F Mercurio

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30 July 2017

A L Oliver

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30 July 2017

S S Thorgeirsson

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30 July 2017

G E Sonenshein

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30 July 2017

language of work or name

English

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publication date

1 August 2000

1 reference

Molecular and Cellular Biology

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

5381-5391

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

30 July 2017

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

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5 July 2018

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5 July 2018

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5 July 2018

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IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

5 July 2018

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Nuclear factor-kappaB/Rel blocks transforming growth factor beta1-induced apoptosis of murine hepatocyte cell lines

5 July 2018

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5 July 2018

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A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

5 July 2018

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Kappa B site-dependent induction of gene expression by diverse inducers of nuclear factor kappa B requires Raf-1.

5 July 2018

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Protein kinase C alpha activates RAF-1 by direct phosphorylation

5 July 2018

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MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells

5 July 2018

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Resistance to inhibition of cell growth by transforming growth factor-beta and its role in oncogenesis

5 July 2018

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Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling

5 July 2018

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Function and activation of NF-kappa B in the immune system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Mammary tumor suppression by transforming growth factor beta 1 transgene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions

5 July 2018

1 reference

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Mutations in the ras proto-oncogene: clues to etiology and molecular pathogenesis of mouse liver tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Neoplastic transformation and lineage switching of rat liver epithelial cells by retrovirus-associated oncogenes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Introduction of a Ha-ras oncogene into rat liver epithelial cells and parenchymal hepatocytes confers resistance to the growth inhibitory effects of TGF-beta.

5 July 2018

1 reference

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Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element.

5 July 2018

1 reference

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In vitro and in vivo association of transforming growth factor-beta 1 with hepatic fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

In vivo differentiation of rat liver oval cells into hepatocytes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

The transforming growth factor-beta family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Altered responsiveness of rat liver epithelial cells to transforming growth factor beta 1 following their transformation with v-raf.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

TGF-beta in liver development, regeneration, and carcinogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Effect of transforming growth factor beta on cell death of cultured rat hepatocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Expression of growth-related genes during tumor progression in v-raf-transformed rat liver epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Growth factors in liver development, regeneration and carcinogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression

5 July 2018

1 reference

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Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C

5 July 2018

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High resolution two-dimensional electrophoresis of proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Oncogenic Ha-Ras-induced Signaling Activates NF-κB Transcriptional Activity, Which Is Required for Cellular Transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

Overexpression of BMP-2 and BMP-4 alters the size and shape of developing skeletal elements in the chick limb

29 October 2018

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Apoptosis as a mechanism of cell death in liver allograft rejection

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85990

A diploid epithelial cell line from normal adult rat liver with phenotypic properties of 'oval' cells.

29 October 2018

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p21Ras downstream effectors are increased in activity or expression in mouse liver tumors but do not differ between ras-mutated and ras-wild-type lesions

29 October 2018

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12 December 2020

Constitutive activation of NF-kappaB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role of tumor necrosis factor and reactive oxygen intermediates

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12 December 2020

An essential role for nuclear factor kappa B in preventing TNF-alpha-induced cell death in prostate cancer cells

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12 December 2020

The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells

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12 December 2020

SIGNAL TRANSDUCTION:IkB Kinases: Kinsmen with Different Crafts

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12 December 2020

Activation of NF-kappaB/Rel occurs early during neoplastic transformation of mammary cells

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12 December 2020

Differential effects of transforming growth factor-beta on proliferation of normal and malignant rat liver epithelial cells in culture

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12 December 2020

Release from G1 growth arrest by transforming growth factor beta 1 requires cellular ras activity

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12 December 2020

Transforming growth factor-beta 1 (TGF-beta 1) and TGF-beta 1 receptors in normal, cirrhotic, and neoplastic human livers

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12 December 2020

Target cell populations in virus-associated hepatocarcinogenesis

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12 December 2020

10.1128/MCB.20.15.5381-5391.2000

Identifiers

DOI

1 reference

release_qvz53aoaiva4vmz6sefl6p4ahu

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qvz53aoaiva4vmz6sefl6p4ahu

24 November 2022

mapped directly with Wikidata item

PMC publication ID

85990

1 reference

30 July 2017

1 reference