The human salivary peptide histatin 5 exerts its antifungal activity through the formation of reactive oxygen species (Q33952105)

30 July 2017

title

The human salivary peptide histatin 5 exerts its antifungal activity through the formation of reactive oxygen species (English)

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30 July 2017

main subject

reactive oxygen species

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E J Helmerhorst

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30 July 2017

R F Troxler

series ordinal

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30 July 2017

F G Oppenheim

series ordinal

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30 July 2017

language of work or name

English

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publication date

20 November 2001

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

14637-14642

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Killing of Candida albicans by histatin 5: cellular uptake and energy requirement

30 July 2017

cites work

2 references

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5 July 2018

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Antimicrobial peptides: properties and applicability

21 January 2018

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Effects of histatin 5 and derived peptides on Candida albicans

5 July 2018

1 reference

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Salivary histatin 5 and human neutrophil defensin 1 kill Candida albicans via shared pathways.

5 July 2018

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Candida albicans mutants deficient in respiration are resistant to the small cationic salivary antimicrobial peptide histatin 5.

5 July 2018

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Histatin 3-mediated killing of Candida albicans: effect of extracellular salt concentration on binding and internalization

5 July 2018

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Oxygen stress: a regulator of apoptosis in yeast

5 July 2018

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Amphotericin B- and fluconazole-resistant Candida spp., Aspergillus fumigatus, and other newly emerging pathogenic fungi are susceptible to basic antifungal peptides

5 July 2018

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Candidacidal activity of salivary histatins. Identification of a histatin 5-binding protein on Candida albicans

5 July 2018

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Human salivary histatin-5 exerts potent fungicidal activity against Cryptococcus neoformans

5 July 2018

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Synthetic histatin analogues with broad-spectrum antimicrobial activity

5 July 2018

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Mitochondrial respiratory chain inhibitors induce apoptosis.

5 July 2018

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Modulation of the in vitro candidacidal activity of human neutrophil defensins by target cell metabolism and divalent cations

5 July 2018

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Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans

5 July 2018

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Structural relationship between human salivary histatins

5 July 2018

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Anticandidal activity of major human salivary histatins

5 July 2018

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The alternate respiratory pathway of Candida albicans

5 July 2018

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Bcl-2 family proteins and mitochondria.

5 July 2018

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Interactions between a new class of eukaryotic antimicrobial agents and isolated rat liver mitochondria

21 January 2018

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Physiological conditions affecting the sensitivity of Saccharomyces cerevisiae to a Pichia kluyveri killer toxin and energy requirement for toxin action.

21 January 2018

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Preparation of highly phosphorylating mitochondria from the yeast Schizosaccharomyces pombe

21 January 2018

1 reference

12 December 2020

The Cellular Target of Histatin 5 onCandida albicansIs the Energized Mitochondrion

1 reference

12 December 2020

Detection of mitochondria-derived reactive oxygen species production by the chemilumigenic probes lucigenin and luminol

1 reference

12 December 2020

Salivary histatin 5 induces non-lytic release of ATP from Candida albicans leading to cell death

1 reference

12 December 2020

Antifungal activities of salivary histidine-rich polypeptides against Candida albicans and other oral yeast isolates

1 reference

12 December 2020

Effect of donor age on the concentrations of histatins in human parotid and submandibular/sublingual saliva

1 reference

12 December 2020

Characterization of Histatin 5 with Respect to Amphipathicity, Hydrophobicity, and Effects on Cell and Mitochondrial Membrane Integrity Excludes a Candidacidal Mechanism of Pore Formation

1 reference

12 December 2020

Mechanism of target cytolysis by peptide defensins. Target cell metabolic activities, possibly involving endocytosis, are crucial for expression of cytotoxicity

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.141366998

1 reference

30 July 2017

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30 July 2017

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