Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae (Q33958350)

30 July 2017

title

Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae (English)

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30 July 2017

main subject

Saccharomyces cerevisiae

1 reference

1 reference

P U Park

1 reference

30 July 2017

P A Defossez

series ordinal

1 reference

30 July 2017

L Guarente

series ordinal

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30 July 2017

language of work or name

English

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publication date

1 May 1999

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Molecular and Cellular Biology

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

3848-3856

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Life span of individual yeast cells

30 July 2017

cites work

1 reference

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5 July 2018

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The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

5 July 2018

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Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

5 July 2018

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Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage

5 July 2018

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Replication focus-forming activity 1 and the Werner syndrome gene product

5 July 2018

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Role of the human RAD51 protein in homologous recombination and double-stranded-break repair

5 July 2018

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Werner helicase is localized to transcriptionally active nucleoli of cycling cells

5 July 2018

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Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases

5 July 2018

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Nucleolar localization of the Werner syndrome protein in human cells

5 July 2018

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Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A

5 July 2018

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Homology-directed repair is a major double-strand break repair pathway in mammalian cells

5 July 2018

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Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

5 July 2018

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Extrachromosomal rDNA circles--a cause of aging in yeast

5 July 2018

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The Yeast Silent Information Regulator Sir4p Anchors and Partitions Plasmids

5 July 2018

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Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA

5 July 2018

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The Werner syndrome protein is a DNA helicase

5 July 2018

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Accelerated Aging and Nucleolar Fragmentation in Yeast sgs1 Mutants

5 July 2018

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Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism

5 July 2018

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Localization of Sir2p: the nucleolus as a compartment for silent information regulators

5 July 2018

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rqh1+, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest

5 July 2018

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Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase

5 July 2018

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Molecular model for telomeric heterochromatin in yeast

5 July 2018

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Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

DNA double-strand breaks caused by replication arrest

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

An unusual form of transcriptional silencing in yeast ribosomal DNA

5 July 2018

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Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination

5 July 2018

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SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Genetic requirements for the single-strand annealing pathway of double-strand break repair in Saccharomyces cerevisiae

5 July 2018

1 reference

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A Rad52 homolog is required for RAD51-independent mitotic recombination in Saccharomyces cerevisiae

5 July 2018

1 reference

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Silencing and heritable domains of gene expression

5 July 2018

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Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

5 July 2018

1 reference

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Positional cloning of the Werner's syndrome gene

5 July 2018

1 reference

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Homologous recombination and the roles of double-strand breaks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

DNA double-strand breaks and the RAD50-RAD57 genes in Saccharomyces.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

The rRNA-encoding DNA array has an altered structure in topoisomerase I mutants of Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

DNA repair genes and proteins of Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Repair of UV-damaged DNA by mammalian cells and Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Biochemistry of homologous recombination in Escherichia coli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Cloning and characterization of RECQL, a potential human homologue of the Escherichia coli DNA helicase RecQ

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

RAD1 and RAD10, but not other excision repair genes, are required for double-strand break-induced recombination in Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Mutation in the silencing gene S/R4 can delay aging in S. cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Daughter cells of Saccharomyces cerevisiae from old mothers display a reduced life span

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Multiple pathways for homologous recombination in Saccharomyces cerevisiae.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Functional Differences and Interactions among the Putative RecA Homologs Rad51, Rad55, and Rad57

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

In vivo biochemistry: physical monitoring of recombination induced by site-specific endonucleases.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

The Bloom's syndrome gene product is homologous to RecQ helicases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Recombinationless meiosis in Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Mitotic chromosome loss in a radiation-sensitive strain of the yeast Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Werner's syndrome: a review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

The double-strand-break repair model for recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

5-Fluoroorotic acid as a selective agent in yeast molecular genetics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

A replication fork barrier at the 3' end of yeast ribosomal RNA genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

The recQ gene of Escherichia coli K12: molecular cloning and isolation of insertion mutants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Mutator phenotype of Werner syndrome is characterized by extensive deletions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

The HML mating-type cassette of Saccharomyces cerevisiae is regulated by two separate but functionally equivalent silencers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Evidence for the involvement of a cytoplasmic factor in the aging of the yeast Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Mutations affecting RNA polymerase I-stimulated exchange and rDNA recombination in yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

A cDNA encoding a human CCAAT-binding protein cloned by functional complementation in yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

A unique pathway of double-strand break repair operates in tandemly repeated genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

The arrest of replication forks in the rDNA of yeast occurs independently of transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Removal of nonhomologous DNA ends in double-strand break recombination: the role of the yeast ultraviolet repair gene RAD1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Telomere maintenance is dependent on activities required for end repair of double-strand breaks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Pedigree analysis of plasmid segregation in yeast

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Increased frequency of 6-thioguanine-resistant peripheral blood lymphocytes in Werner syndrome patients.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84236

Topoisomerases and yeast rRNA transcription: negative supercoiling stimulates initiation and topoisomerase activity is required for elongation

29 October 2018

1 reference

12 December 2020

Construction of new T vectors for direct cloning of PCR products

1 reference

12 December 2020

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

1 reference

12 December 2020

Genetic evidence for different RAD52-dependent intrachromosomal recombination pathways in Saccharomyces cerevisiae

1 reference

12 December 2020

Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae

1 reference

12 December 2020

A subthreshold level of DNA topoisomerases leads to the excision of yeast rDNA as extrachromosomal rings

1 reference

12 December 2020

The RAD50 gene, a member of the double strand break repair epistasis group, is not required for spontaneous mitotic recombination in yeast

1 reference

12 December 2020

Flow cytometry and cell sorting for yeast viability assessment and cell selection

1 reference

12 December 2020

Experiments on ageing in single cells of Saccharomyces cerevisiae

1 reference

12 December 2020

Defective excision of pyrimidine dimers and interstrand DNA crosslinks in rad7 and rad23 mutants of Saccharomyces cerevisiae

1 reference

12 December 2020

Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae

1 reference

12 December 2020

RuvAB acts at arrested replication forks

1 reference

12 December 2020

Parental age and the life-span of zygotes of Saccharomyces cerevisiae

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.19.5.3848

1 reference

30 July 2017

1 reference

30 July 2017

1 reference