Evidence for a role for transglutaminase in Huntington's disease and the potential therapeutic implications (Q33956314)

30 July 2017

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title

Evidence for a role for transglutaminase in Huntington's disease and the potential therapeutic implications (English)

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30 July 2017

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Marcela V Karpuj

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30 July 2017

Mark W Becher

series ordinal

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30 July 2017

Lawrence Steinman

series ordinal

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30 July 2017

publication date

1 January 2002

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Neurochemistry International

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

31-36

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Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length

30 July 2017

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Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease.

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Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins

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Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch.

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Peptides containing glutamine repeats as substrates for transglutaminase-catalyzed cross-linking: relevance to diseases of the nervous system

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Transglutaminase action imitates Huntington's disease: selective polymerization of Huntingtin containing expanded polyglutamine.

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Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei

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7 January 2021

Distinct nuclear localization and activity of tissue transglutaminase

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Specificity of guinea pig liver transglutaminase for amine substrates

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Neurodegenerative diseases and transglutaminase

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7 January 2021

Amyloid-like inclusions in Huntington's disease.

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Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

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7 January 2021

Reversing neurodegeneration: a promise unfolds

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Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.

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7 January 2021

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

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Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

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7 January 2021

Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

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7 January 2021

10.1016/S0197-0186(01)00060-2

Identifiers

DOI

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30 July 2017

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