A yeast-based assay identifies drugs active against human mitochondrial disorders (Q33946234)

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6 February 2020

title

A yeast-based assay identifies drugs active against human mitochondrial disorders (English)

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6 February 2020

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6 February 2020

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6 February 2020

Elodie Couplan

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6 February 2020

Raeka S Aiyar

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6 February 2020

Anna Kabala

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Nahia Ezkurdia

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6 February 2020

Robert P St Onge

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Bénédicte Salin

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6 February 2020

Flavie Soubigou

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6 February 2020

Marie Le Cann

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6 February 2020

Jean-Paul di Rago

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6 February 2020

language of work or name

English

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publication date

29 June 2011

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Proceedings of the National Academy of Sciences of the United States of America

6 February 2020

published in

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volume

108

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issue

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page(s)

11989-11994

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Mitochondrial DNA mutations and human disease

6 February 2020

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A yeast-based assay to isolate drugs active against mammalian prions

28 July 2018

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High-efficiency biolistic transformation of Chlamydomonas mitochondria can be used to insert mutations in complex I genes

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Mss51p and Cox14p jointly regulate mitochondrial Cox1p expression in Saccharomyces cerevisiae

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The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants

28 July 2018

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Genome-wide responses to mitochondrial dysfunction

28 July 2018

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Identification of a nuclear gene (FMC1) required for the assembly/stability of yeast mitochondrial F(1)-ATPase in heat stress conditions

28 July 2018

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28 July 2018

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28 July 2018

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21 January 2018

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Isolation of drugs active against mammalian prions using a yeast-based screening assay

21 January 2018

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Failure to assemble the alpha 3 beta 3 subcomplex of the ATP synthase leads to accumulation of the alpha and beta subunits within inclusion bodies and the loss of mitochondrial cristae in Saccharomyces cerevisiae

21 January 2018

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The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine

21 January 2018

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ATO3 encoding a putative outward ammonium transporter is an RTG-independent retrograde responsive gene regulated by GCN4 and the Ssy1-Ptr3-Ssy5 amino acid sensor system

21 January 2018

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21 January 2018

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Impact on oxidative phosphorylation of immortalization with the telomerase gene

21 January 2018

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Biochemical consequences in yeast of the human mitochondrial DNA 8993T>C mutation in the ATPase6 gene found in NARP/MILS patients

21 January 2018

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29 October 2018

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Genetic transformation of Saccharomyces cerevisiae mitochondria

29 October 2018

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12 December 2020

The biogenesis and assembly of photosynthetic proteins in thylakoid membranes1

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12 December 2020

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1101478108

1 reference

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6 February 2020

0 references

1 reference

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PubMed publication ID

21715656

1 reference

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