Reduced PU.1 expression causes myeloid progenitor expansion and increased leukemia penetrance in mice expressing PML-RARalpha. (Q33920326)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16113082%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Reduced PU.1 expression causes myeloid progenitor expansion and increased leukemia penetrance in mice expressing PML-RARalpha (English)

1 reference

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5 January 2020

1 reference

1 reference

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5 January 2020

Elaine R Mardis

1 reference

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5 January 2020

Rhonda E Ries

1 reference

5 January 2020

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Matthew J Walter

1 reference

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5 January 2020

John S Park

1 reference

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5 January 2020

Michael McLellan

1 reference

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5 January 2020

Sara Jaeger

1 reference

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5 January 2020

Richard K Wilson

1 reference

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5 January 2020

Timothy J Ley

1 reference

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5 January 2020

language of work or name

English

0 references

publication date

19 August 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16113082%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

5 January 2020

published in

1 reference

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5 January 2020

volume

102

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5 January 2020

issue

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5 January 2020

page(s)

12513-12518

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Mutations of the PU.1 Ets domain are specifically associated with murine radiation-induced, but not human therapy-related, acute myeloid leukaemia

5 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Neutrophil elastase is important for PML-retinoic acid receptor alpha activities in early myeloid cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Expression profiling of murine acute promyelocytic leukemia cells reveals multiple model-dependent progression signatures

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Neutrophil elastase cleaves PML-RARalpha and is important for the development of acute promyelocytic leukemia in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

C/EBP-beta, C/EBP-delta, PU.1, AML1 genes: mutational analysis in 381 samples of hematopoietic and solid malignancies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor alpha chimeric protein (PMLRARalpha) to block neutrophil differentiation and initiate acute leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Acquired, nonrandom chromosomal abnormalities associated with the development of acute promyelocytic leukemia in transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

A bcr-3 isoform of RARalpha-PML potentiates the development of PML-RARalpha-driven acute promyelocytic leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Characterization of genetic instability in radiation- and benzene-induced murine acute leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Advantages of the CBA mouse in leukemogenesis research

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Seed versus soil: the importance of the target cell for transgenic models of human leukemias.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Molecular mapping of chromosome 2 deletions in murine radiation-induced AML localizes a putative tumor suppressor gene to a 1.0 cM region homologous to human chromosome segment 11p11-12.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Expression of the transcription factor, Spi-1 (PU.1), in differentiating murine erythroleukemia cells Is regulated post-transcriptionally. Evidence for differential stability of transcription factor mRNAs following inducer exposure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

WT-1 is required for early kidney development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Early myeloid cell-specific expression of the human cathepsin G gene in transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

The dose-response for x-ray induction of myeloid leukaemia in male CBA/H mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504247102

Heterozygous PU.1 mutations are associated with acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504247102

Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504247102

PU.1 is a suppressor of myeloid leukemia, inactivated in mice by gene deletion and mutation of its DNA binding domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504247102

Role of the WT1 tumor suppressor in murine hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504247102

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504247102

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice identify cooperating events and genetic pathways to acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504247102

Comparative analysis of genes regulated by PML/RAR alpha and PLZF/RAR alpha in response to retinoic acid using oligonucleotide arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504247102

CD44-deficient mice develop normally with changes in subpopulations and recirculation of lymphocyte subsets.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

Initiation and promotion in radiation-induced myeloid leukemia

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188022

The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia

29 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504247102

Chromosomal aberrations observed in 52 mouse myeloid leukemias

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16113082

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Deletion of chromosome 2 is an early event in the development of radiation-induced myeloid leukemia in SJL/J mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16113082

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Altered myeloid development and acute leukemia in transgenic mice expressing PML-RAR alpha under control of cathepsin G regulatory sequences

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16113082

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0504247102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16113082%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

0 references

1 reference

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5 January 2020

PubMed publication ID

16113082

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16113082%20AND%20SRC:MED&resulttype=core&format=json