The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis. (Q33929406)

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31 January 2020

title

The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis (English)

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31 January 2020

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31 January 2020

Kwang-Pyo Lee

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31 January 2020

Joo-Hyeon Lee

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31 January 2020

Tae-Shin Kim

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31 January 2020

Tack-Hoon Kim

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31 January 2020

Hee-Dong Park

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31 January 2020

Jin-Seok Byun

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31 January 2020

Min-Chul Kim

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31 January 2020

Won-Il Jeong

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31 January 2020

Diego F Calvisi

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31 January 2020

Jin-Man Kim

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31 January 2020

language of work or name

English

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publication date

19 April 2010

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Proceedings of the National Academy of Sciences of the United States of America

31 January 2020

published in

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31 January 2020

volume

107

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31 January 2020

issue

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31 January 2020

page(s)

8248-8253

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Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

31 January 2020

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Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

5 July 2018

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Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma

5 July 2018

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Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)

5 July 2018

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TEAD mediates YAP-dependent gene induction and growth control

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Deletion of the Met tyrosine kinase in liver progenitor oval cells increases sensitivity to apoptosis in vitro

5 July 2018

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A crucial role of WW45 in developing epithelial tissues in the mouse

5 July 2018

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The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals

5 July 2018

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Tumor suppressor LATS1 is a negative regulator of oncogene YAP

5 July 2018

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YAP1 increases organ size and expands undifferentiated progenitor cells

5 July 2018

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

5 July 2018

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Elucidation of a universal size-control mechanism in Drosophila and mammals

5 July 2018

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Origin of hepatocellular carcinoma: role of stem cells

5 July 2018

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Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

5 July 2018

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Liver stem cells and their implication in hepatocellular and cholangiocarcinoma

5 July 2018

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Liver stem cells and prospects for liver reconstitution by transplanted cells

5 July 2018

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Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65

5 July 2018

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TWEAK induces liver progenitor cell proliferation

5 July 2018

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5 July 2018

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5 July 2018

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Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity

5 July 2018

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5 July 2018

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5 July 2018

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Mouse A6-positive hepatic oval cells also express several hematopoietic stem cell markers

5 July 2018

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5 July 2018

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salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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21 January 2018

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21 January 2018

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Dose- and time-dependent oval cell reaction in acetaminophen-induced murine liver injury.

21 January 2018

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The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.

21 January 2018

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Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver

21 January 2018

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21 January 2018

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Primary liver tumour of intermediate (hepatocyte-bile duct cell) phenotype: a progenitor cell tumour?

21 January 2018

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PubMed

12 December 2020

Atypical ductular proliferation and its inhibition by transforming growth factor beta1 in the 3,5-diethoxycarbonyl-1,4-dihydrocollidine mouse model for chronic alcoholic liver disease

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PubMed

12 December 2020

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12 December 2020

Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0912203107

1 reference

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31 January 2020

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release_3fs32t3shnf6jkwum6tutajtbe

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Fatcat

https://api.fatcat.wiki/v0/release/3fs32t3shnf6jkwum6tutajtbe

24 November 2022

mapped directly with Wikidata item

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31 January 2020

PubMed publication ID

20404163

1 reference

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