A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus (Q33928650)

30 July 2017

title

A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus (English)

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respiratory syncytial virus

30 July 2017

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John DeVincenzo

1 reference

30 July 2017

Robert Lambkin-Williams

object named as

Robert Lambkin-Williams

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30 July 2017

Tom Wilkinson

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30 July 2017

Jeffrey Cehelsky

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30 July 2017

Sara Nochur

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30 July 2017

Edward Walsh

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30 July 2017

Rachel Meyers

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30 July 2017

Jared Gollob

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30 July 2017

Akshay Vaishnaw

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30 July 2017

language of work or name

English

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publication date

26 April 2010

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

107

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30 July 2017

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30 July 2017

page(s)

8800-8805

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RNA interference-mediated silencing of the respiratory syncytial virus nucleocapsid defines a potent antiviral strategy

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Births: final data for 2005.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Palivizumab and the prevention of respiratory syncytial virus illness in pediatric patients with congenital heart disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Comparison of a real-time reverse transcriptase PCR assay and a culture technique for quantitative assessment of viral load in children naturally infected with respiratory syncytial virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Respiratory syncytial virus infection in elderly and high-risk adults

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Mortality associated with influenza and respiratory syncytial virus in the United States

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Respiratory syncytial virus and parainfluenza virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Specific interference with gene function by double-stranded RNA in early mouse development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889365

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912186107

RNAi-mediated gene silencing in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912186107

Knocking down disease with siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912186107

Inhibition of respiratory viruses by nasally administered siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912186107

Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912186107

Experimental infection of humans with A2 respiratory syncytial virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912186107

Elevated cytokine concentrations in the nasopharyngeal and tracheal secretions of children with respiratory syncytial virus disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912186107

Nasal quantity of respiratory syncytical virus correlates with disease severity in hospitalized infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912186107

Respiratory syncytial virus load predicts disease severity in previously healthy infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912186107

Natural infection of infants with respiratory syncytial virus subgroups A and B: a study of frequency, disease severity, and viral load

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912186107

Serum antibody decay in adults following natural respiratory syncytial virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912186107

21 January 2018

Identifiers

DOI

10.1073/PNAS.0912186107

1 reference

release_3wsbxbigdzhwna2cleyl5nbovm

30 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3wsbxbigdzhwna2cleyl5nbovm

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

2889365

1 reference

30 July 2017

1 reference