Mechanistic similarity and diversity among the guanidine-modifying members of the pentein superfamily (Q33925308)

30 July 2017

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title

Mechanistic similarity and diversity among the guanidine-modifying members of the pentein superfamily (English)

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30 July 2017

Thomas Linsky

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30 July 2017

Walter Fast

series ordinal

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30 July 2017

language of work or name

English

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publication date

21 July 2010

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Biochimica et Biophysica Acta

30 July 2017

published in

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30 July 2017

volume

1804

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30 July 2017

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30 July 2017

page(s)

1943-1953

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Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3.

30 July 2017

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Mechanisms of catalysis and inhibition operative in the arginine deiminase from the human pathogen Giardia lamblia

5 July 2018

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Active site cysteine is protonated in the PAD4 Michaelis complex: evidence from Born-Oppenheimer ab initio QM/MM molecular dynamics simulations

5 July 2018

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The chemical versatility of the beta-alpha-beta fold: catalytic promiscuity and divergent evolution in the tautomerase superfamily

5 July 2018

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Promiscuous Partitioning of a Covalent Intermediate Common in the Pentein Superfamily

5 July 2018

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Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis.

5 July 2018

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Protein arginine deiminase 4: evidence for a reverse protonation mechanism

5 July 2018

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Disruption of methylarginine metabolism impairs vascular homeostasis

5 July 2018

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The gene cluster for agmatine catabolism of Enterococcus faecalis: study of recombinant putrescine transcarbamylase and agmatine deiminase and a snapshot of agmatine deiminase catalyzing its reaction

5 July 2018

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Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization.

5 July 2018

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5 July 2018

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Evolution of enzyme superfamilies

5 July 2018

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N-Succinylated intermediates in an arginine catabolic pathway of Pseudomonas aeruginosa

5 July 2018

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Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis

5 July 2018

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Characterization of a transient covalent adduct formed during dimethylarginine dimethylaminohydrolase catalysis

5 July 2018

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Crystal structure of N-succinylarginine dihydrolase AstB, bound to substrate and product, an enzyme from the arginine catabolic pathway of Escherichia coli

5 July 2018

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Divergent evolution in the enolase superfamily: the interplay of mechanism and specificity

5 July 2018

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5 July 2018

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Structural insight into arginine degradation by arginine deiminase, an antibacterial and parasite drug target

5 July 2018

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Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase

5 July 2018

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Determination of protein function, evolution and interactions by structural genomics.

5 July 2018

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Divergent evolution of enzymatic function: mechanistically diverse superfamilies and functionally distinct suprafamilies

5 July 2018

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Crystal structures of ribosome anti-association factor IF6

5 July 2018

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Catalytic promiscuity and the evolution of new enzymatic activities

5 July 2018

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Crystal structure of L-arginine:inosamine-phosphate amidinotransferase StrB1 from Streptomyces griseus: an enzyme involved in streptomycin biosynthesis

5 July 2018

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Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli

5 July 2018

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Substrate Binding and Catalysis by L‐arginine: Glycine Amidinotransferase — A Mutagenesis and Crystallographic Study

5 July 2018

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5 July 2018

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Structure and reaction mechanism of L-arginine:glycine amidinotransferase

5 July 2018

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The effect of growth hormone and thyroxine on the amount of L-arginine:glycine amidinotransferase in kidneys of hypophysectomized rats. Purification and some properties of rat kidney transamidinase

5 July 2018

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Occurrence of succinyl derivatives in the catabolism of arginine in Pseudomonas cepacia

5 July 2018

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The electrostatic driving force for nucleophilic catalysis in L-arginine deiminase: a combined experimental and theoretical study

5 July 2018

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Inactivation of microbial arginine deiminases by L-canavanine

29 October 2018

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Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-L-homocysteine and hydrogen peroxide. Analysis, quantification, and implications for hyperhomocysteinemia

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104755

Structure of the mammalian NOS regulator dimethylarginine dimethylaminohydrolase: A basis for the design of specific inhibitors

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104755

Kinetic analysis of Pseudomonas aeruginosa arginine deiminase mutants and alternate substrates provides insight into structural determinants of function.

29 October 2018

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Crystal structures representing the Michaelis complex and the thiouronium reaction intermediate of Pseudomonas aeruginosa arginine deiminase.

29 October 2018

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Arginine deiminase uses an active-site cysteine in nucleophilic catalysis of L-arginine hydrolysis

29 October 2018

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Crystal structures of arginine deiminase with covalent reaction intermediates; implications for catalytic mechanism.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104755

Biosynthesis of guanidinoacetic acid. I. Purification and properties of transamidinase.

29 October 2018

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Identification and characterization of plant agmatine iminohydrolase, the last missing link in polyamine biosynthesis of plants

29 October 2018

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An elusive propeller-like fold

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104755

Substrate-assisted cysteine deprotonation in the mechanism of dimethylargininase (DDAH) from Pseudomonas aeruginosa

29 October 2018

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12 December 2020

The guanidino-group modifying enzymes: structural basis for their diversity and commonality

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12 December 2020

Transamidinase of hog kidney. V. Kinetic studies

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12 December 2020

Transamidinase of hog kidney. VII. Cysteine at the amidine-binding site

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12 December 2020

Arginine-ornithine transamidination in kidney

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12 December 2020

10.1016/J.BBAPAP.2010.07.016

Identifiers

DOI

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30 July 2017

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30 July 2017

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