Genetics of acquired long QT syndrome (Q33905822)

29 July 2017

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title

Genetics of acquired long QT syndrome (English)

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29 July 2017

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Dan M Roden

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29 July 2017

author name string

Prakash C Viswanathan

series ordinal

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29 July 2017

language of work or name

English

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publication date

1 August 2005

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Journal of Clinical Investigation

29 July 2017

published in

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29 July 2017

volume

115

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29 July 2017

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29 July 2017

page(s)

2025-2032

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Long QT syndrome: from channels to cardiac arrhythmias

29 July 2017

cites work

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28 July 2018

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28 July 2018

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28 July 2018

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Evaluation of drug-induced QT interval prolongation: implications for drug approval and labelling

28 July 2018

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A structural basis for drug-induced long QT syndrome

28 July 2018

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The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs: clinical and regulatory implications. Report on a policy conference of the European Society of Cardiology

28 July 2018

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Differential effects of beta-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome.

28 July 2018

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Pause induced early afterdepolarizations in the long QT syndrome: a simulation study

28 July 2018

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Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation

28 July 2018

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Dofetilide in patients with congestive heart failure and left ventricular dysfunction. Danish Investigations of Arrhythmia and Mortality on Dofetilide Study Group

28 July 2018

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MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia

28 July 2018

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Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome

28 July 2018

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Family History as a Risk Factor for Primary Cardiac Arrest

28 July 2018

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A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG

28 July 2018

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A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes

28 July 2018

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Rapid inactivation determines the rectification and [K+]o dependence of the rapid component of the delayed rectifier K+ current in cardiac cells.

28 July 2018

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28 July 2018

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A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

28 July 2018

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Characteristics of the delayed rectifier current (IKr and IKs) in canine ventricular epicardial, midmyocardial, and endocardial myocytes. A weaker IKs contributes to the longer action potential of the M cell

28 July 2018

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A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

28 July 2018

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Effects of verapamil and propranolol on early afterdepolarizations and ventricular arrhythmias induced by epinephrine in congenital long QT syndrome

28 July 2018

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Proarrhythmic effects of a quinidine analog in dogs with chronic A-V block

28 July 2018

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Bradycardia-dependent triggered activity: relevance to drug-induced multiform ventricular tachycardia

28 July 2018

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Ventricular tachycardia with 2 variable opposing foci

28 July 2018

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Action potential prolongation and induction of abnormal automaticity by low quinidine concentrations in canine Purkinje fibers. Relationship to potassium and cycle length

28 July 2018

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Incidence and clinical features of the quinidine-associated long QT syndrome: implications for patient care

28 July 2018

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Treatment of torsade de pointes with magnesium sulfate

28 July 2018

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Pharmacological response of quinidine induced early afterdepolarisations in canine cardiac Purkinje fibres: insights into underlying ionic mechanisms

28 July 2018

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The long QT syndromes: a critical review, new clinical observations and a unifying hypothesis

28 July 2018

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Amiodarone and torsade de pointes

28 July 2018

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Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction

28 July 2018

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Erythromycin-induced long QT syndrome: concordance with quinidine and underlying cellular electrophysiologic mechanism

28 July 2018

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A model of the ventricular cardiac action potential. Depolarization, repolarization, and their interaction

28 July 2018

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QTU-prolongation and torsades de pointes induced by putative class III antiarrhythmic agents in the rabbit: etiology and interventions

28 July 2018

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Amplified transmural dispersion of repolarization as the basis for arrhythmogenesis in a canine ventricular-wedge model of short-QT syndrome

28 July 2018

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Arrhythmogenic mechanisms of QT prolonging drugs: is QT prolongation really the problem?

29 October 2018

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Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties

29 October 2018

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Physicochemical features of the HERG channel drug binding site

29 October 2018

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29 October 2018

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Long QT syndrome caused by noncardiac drugs

29 October 2018

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Unique topographical distribution of M cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome

29 October 2018

1 reference

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Larger late sodium conductance in M cells contributes to electrical heterogeneity in canine ventricle

29 October 2018

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A common polymorphism associated with antibiotic-induced cardiac arrhythmia

29 October 2018

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Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias

29 October 2018

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QT dispersion as a predictor of long-term mortality in patients with acute myocardial infarction and clinical evidence of heart failure

29 October 2018

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Prolonged QT interval predicts cardiac and all-cause mortality in the elderly. The Rotterdam Study

29 October 2018

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Normalization of acquired QT prolongation in humans by intravenous potassium.

29 October 2018

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Spontaneous sequences of onset of torsade de pointes in patients with acquired prolonged repolarization: quantitative analysis of Holter recordings

29 October 2018

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Transmural electrophysiological heterogeneities underlying arrhythmogenesis in heart failure

29 October 2018

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12 December 2020

Ethnic differences in cardiac potassium channel variants: implications for genetic susceptibility to sudden cardiac death and genetic testing for congenital long QT syndrome

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12 December 2020

Genetic variations of KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 in drug-induced long QT syndrome patients

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12 December 2020

Electrophysiologial and beta-receptor blocking effects of MJ 1999 on dog and rabbit cardiac tissue

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12 December 2020

QT interval prolongation as predictor of sudden death in patients with myocardial infarction

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12 December 2020

Role of Na+:Ca2+ exchange current in Cs(+)-induced early afterdepolarizations in Purkinje fibers

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12 December 2020

Predicting sudden death in the population: the Paris Prospective Study I

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12 December 2020

In vivo and in vitro antiarrhythmic and arrhythmogenic effects of N-acetyl procainamide

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12 December 2020

Torsade de pointes: the long-short initiating sequence and other clinical features: observations in 32 patients

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12 December 2020

Extracellular potassium modulation of drug block of IKr. Implications for torsade de pointes and reverse use-dependence

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12 December 2020

Cisapride and fatal arrhythmia

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12 December 2020

KVLQT1 C-Terminal Missense Mutation Causes a Forme Fruste Long-QT Syndrome

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12 December 2020

Modulation of HERG affinity for E-4031 by [K+]o and C-type inactivation

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12 December 2020

Taking the "idio" out of "idiosyncratic": predicting torsades de pointes

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12 December 2020

Cellular basis of biventricular hypertrophy and arrhythmogenesis in dogs with chronic complete atrioventricular block and acquired torsade de pointes

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12 December 2020

Acceleration-induced action potential prolongation and early afterdepolarizations

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12 December 2020

Calmodulin kinase inhibition prevents development of the arrhythmogenic transient inward current

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12 December 2020

Effects of IKr and IKs heterogeneity on action potential duration and its rate dependence: a simulation study

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12 December 2020

Exaggerated QT prolongation after cardioversion of atrial fibrillation

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12 December 2020

Mechanism of the cardiotoxic actions of terfenadine

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12 December 2020

QT dispersion and sudden unexpected death in chronic heart failure

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12 December 2020

Proarrhythmic effects of the class III agent almokalant: importance of infusion rate, QT dispersion, and early afterdepolarisations

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12 December 2020

Sudden cardiac death in heart failure. The role of abnormal repolarization

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12 December 2020

A sensitive mechanism for cation modulation of potassium current

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12 December 2020

Effect of dofetilide in patients with recent myocardial infarction and left-ventricular dysfunction: a randomised trial

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12 December 2020

Transmural dispersion of repolarization and the T wave

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12 December 2020

Pause-dependent torsade de pointes following acute myocardial infarction: a variant of the acquired long QT syndrome

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI25539

1 reference

29 July 2017

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29 July 2017

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