Growth suppression induced by downregulation of E6-AP expression in human papillomavirus-positive cancer cell lines depends on p53 (Q33883959)

29 July 2017

title

Growth suppression induced by downregulation of E6-AP expression in human papillomavirus-positive cancer cell lines depends on p53 (English)

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29 July 2017

main subject

human papilloma virus

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human papillomavirus

29 September 2024

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29 July 2017

Felix Hoppe-Seyler

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29 July 2017

Arnd Hengstermann

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29 July 2017

Michael A D'silva

series ordinal

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29 July 2017

Petric Kuballa

series ordinal

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29 July 2017

Karin Butz

series ordinal

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29 July 2017

publication date

1 July 2005

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29 July 2017

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

9296-9300

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The global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase

29 July 2017

cites work

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HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53.

5 July 2018

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siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells

5 July 2018

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E6AP gene suppression and characterization with in vitro selected hammerhead ribozymes.

5 July 2018

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Human papillomavirus-induced carcinogenesis and the ubiquitin-proteasome system

5 July 2018

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5 July 2018

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5 July 2018

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Human papillomavirus E6-induced degradation of E6TP1 is mediated by E6AP ubiquitin ligase.

5 July 2018

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The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

5 July 2018

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5 July 2018

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The human papillomavirus E6 protein and its contribution to malignant progression

5 July 2018

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Activation and activities of the p53 tumour suppressor protein

5 July 2018

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Mechanisms underlying ubiquitination

5 July 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

5 July 2018

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Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells

5 July 2018

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Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

5 July 2018

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Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase

5 July 2018

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Induction of apoptosis in human papillomaviruspositive cancer cells by peptide aptamers targeting the viral E6 oncoprotein

5 July 2018

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Stress signals utilize multiple pathways to stabilize p53

5 July 2018

1 reference

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Characterization of sequence elements involved in p53 stability regulation reveals cell type dependence for p53 degradation

5 July 2018

1 reference

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The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.

5 July 2018

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The human E6-AP gene (UBE3A) encodes three potential protein isoforms generated by differential splicing

5 July 2018

1 reference

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Antisense targeting of E6AP elevates p53 in HPV-infected cells but not in normal cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168765

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168765

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168765

Viruses and the 26S proteasome: hacking into destruction

5 July 2018

1 reference

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Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168765

10.1128/JVI.79.14.9296-9300.2005

29 October 2018

Identifiers

DOI

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29 July 2017

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29 July 2017

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