Characterization of CD4+ T cells specific for glutamic acid decarboxylase (GAD65) and proinsulin in a patient with stiff-person syndrome but without type 1 diabetes (Q33884262)

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English	Characterization of CD4+ T cells specific for glutamic acid decarboxylase (GAD65) and proinsulin in a patient with stiff-person syndrome but without type 1 diabetes	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Characterization of CD4+ T cells specific for glutamic acid decarboxylase (GAD65) and proinsulin in a patient with stiff-person syndrome but without type 1 diabetes (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

type-1 diabetes

0 references

stiff-person syndrome

1 reference

based on heuristic

inferred from title

object named as

Arno Hänninen

1

0 references

Christiane S Hampe

object named as

Christiane S Hampe

3

0 references

object named as

Jorma Ilonen

6

0 references

object named as

Mikael Knip

7

0 references

author name string

Merja Soilu-Hänninen

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Angie Deptula

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Kelly Geubtner

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Helena Reijonen

8

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

publication date

1 May 2010

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Diabetes - Metabolism: Research and Reviews

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

26

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

271-279

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

The role of T helper subsets in autoimmunity and allergy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Stiff person syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Cerebrospinal fluid T cell responses against glutamic acid decarboxylase 65 in patients with stiff person syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Autoimmune mechanisms in type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Cellular and molecular pathogenesis of type 1A diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Reconstitution of paired T cell receptor alpha- and beta-chains from microdissected single cells of human inflammatory tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Diabetes mellitus: pathogenesis and treatment strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

HLA DR-DQ-encoded genetic determinants of childhood-onset type 1 diabetes in Finland: an analysis of 622 nuclear families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Use of HLA class II tetramers in tracking antigen-specific T cells and mapping T-cell epitopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

A novel monoclonal antibody specific for the N-terminal end of GAD65.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Recognition of glutamic acid decarboxylase (GAD) by autoantibodies from different GAD antibody-positive phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Distinct T cell interactions with HLA class II tetramers characterize a spectrum of TCR affinities in the human antigen-specific T cell response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

MHC class II tetramers identify peptide-specific human CD4(+) T cells proliferating in response to influenza A antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

The stiff-person syndrome: an autoimmune disorder affecting neurotransmission of gamma-aminobutyric acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Rapid screening of T-cell receptor (TCR) variable gene usage by multiplex PCR: application for assessment of clonal composition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Humoral and cellular immune parameters before and during immunosuppressive therapy of a patient with stiff-man syndrome and insulin dependent diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Prediction of IDDM in the General Population: Strategies Based on Combinations of Autoantibody Markers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

T cell autoimmunity to glutamic acid decarboxylase in human insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

The exon-intron organization of the genes (GAD1 and GAD2) encoding two human glutamate decarboxylases (GAD67 and GAD65) suggests that they derive from a common ancestral GAD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

GAD autoantibodies in IDDM, stiff-man syndrome, and autoimmune polyendocrine syndrome type I recognize different epitopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Two genes encode distinct glutamate decarboxylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Autoimmunity to glutamic acid decarboxylase (GAD) in stiffman syndrome and insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Recombinant glutamic acid decarboxylase (representing the single isoform expressed in human islets) detects IDDM-associated 64,000-M(r) autoantibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Human monoclonal islet cell antibodies from a patient with insulin-dependent diabetes mellitus reveal glutamate decarboxylase as the target antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

5 July 2018

Stiff person syndrome: quantification, specificity, and intrathecal synthesis of GAD65 antibodies

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.1083

21 January 2018

Analysis of GAD65 autoantibodies in Stiff-Person syndrome patients

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.1083

21 January 2018

Stiff person syndrome: advances in pathogenesis and therapeutic interventions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

29 October 2018

GAD65 as a prototypic autoantigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

29 October 2018

Brain gamma-aminobutyric acid changes in stiff-person syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

29 October 2018

GAD65-specific CD4+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

29 October 2018

Detection of CD4+ autoreactive T cells in T1D using HLA class II tetramers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

29 October 2018

Humoral and Cellular Autoimmune Responses in Stiff Person Syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

29 October 2018

Immune reactivity to glutamic acid decarboxylase 65 in stiffman syndrome and type 1 diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

29 October 2018

Inhibition of gamma-aminobutyric acid synthesis by glutamic acid decarboxylase autoantibodies in stiff-man syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

29 October 2018

IA-2 antibodies--a sensitive marker of IDDM with clinical onset in childhood and adolescence. Childhood Diabetes in Finland Study Group.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

29 October 2018

Human B Cells Secreting Immunoglobulin G to Glutamic Acid Decarboxylase-65 from a Nondiabetic Patient with Multiple Autoantibodies and Graves’ Disease: A Comparison with Those Present in Type 1 Diabetes1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

29 October 2018

GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878280

29 October 2018

Identification of glutamic acid decarboxylase autoantibody heterogeneity and epitope regions in type I diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20503259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoantibodies associated with Type I diabetes mellitus persist after diagnosis in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/20503259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two distinct glutamic acid decarboxylase auto-antibody specificities in IDDM target different epitopes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20503259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell reactivity to glutamic acid decarboxylase in stiff-man syndrome and cerebellar ataxia associated with polyendocrine autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20503259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamic acid decarboxylase autoantibodies in stiff-man syndrome and insulin-dependent diabetes mellitus exhibit similarities and differences in epitope recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/20503259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamic acid decarboxylase T lymphocyte responses associated with susceptibility or resistance to type I diabetes: analysis in disease discordant human twins, non-obese diabetic mice and HLA-DQ transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20503259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pregnancy induces nonimmunoglobulin insulin-binding activity in both maternal and cord blood serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/20503259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunodominant epitopes of glutamic acid decarboxylase 65 and 67 in insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20503259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GAD65-Reactive T cells in a non-diabetic stiff-man syndrome patient

1 reference

https://pubmed.ncbi.nlm.nih.gov/20503259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant Fabs of human monoclonal antibodies specific to the middle epitope of GAD65 inhibit type 1 diabetes-specific GAD65Abs

1 reference

https://pubmed.ncbi.nlm.nih.gov/20503259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High diagnostic sensitivity of glutamate decarboxylase autoantibodies in insulin-dependent diabetes mellitus with clinical onset between age 20 and 40 years. The Belgian Diabetes Registry

1 reference

https://pubmed.ncbi.nlm.nih.gov/20503259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/DMRR.1083

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

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