Orlistat, a new lipase inhibitor for the management of obesity (Q33871474)

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scientific article published in March 2000

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English	Orlistat, a new lipase inhibitor for the management of obesity	scientific article published in March 2000

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PMC publication ID

6145169

retrieved

2 July 2019

reference URL

http://europepmc.org/abstract/PMC/6145169

review article

1 reference

stated in

Europe PubMed Central

title

Orlistat, a new lipase inhibitor for the management of obesity (English)

1 reference

stated in

Europe PubMed Central

PMC publication ID

6145169

retrieved

2 July 2019

reference URL

http://europepmc.org/abstract/PMC/6145169

main subject

obesity

0 references

triacylglycerol lipase inhibitor

1 reference

based on heuristic

inferred from title

author

Jack A Yanovski

series ordinal

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

10730683

retrieved

29 July 2017

author name string

A M Heck

series ordinal

1

1 reference

stated in

Europe PubMed Central

PMC publication ID

6145169

retrieved

2 July 2019

reference URL

http://europepmc.org/abstract/PMC/6145169

K A Calis

series ordinal

3

1 reference

stated in

Europe PubMed Central

PMC publication ID

6145169

retrieved

2 July 2019

reference URL

http://europepmc.org/abstract/PMC/6145169

language of work or name

English

0 references

publication date

1 March 2000

1 reference

stated in

Europe PubMed Central

PMC publication ID

6145169

retrieved

2 July 2019

reference URL

http://europepmc.org/abstract/PMC/6145169

published in

Pharmacotherapy

1 reference

stated in

Europe PubMed Central

PMC publication ID

6145169

retrieved

2 July 2019

reference URL

http://europepmc.org/abstract/PMC/6145169

volume

20

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stated in

Europe PubMed Central

PMC publication ID

6145169

retrieved

2 July 2019

reference URL

http://europepmc.org/abstract/PMC/6145169

issue

3

1 reference

stated in

Europe PubMed Central

PMC publication ID

6145169

retrieved

2 July 2019

reference URL

http://europepmc.org/abstract/PMC/6145169

page(s)

270-279

1 reference

stated in

Europe PubMed Central

PMC publication ID

6145169

retrieved

2 July 2019

reference URL

http://europepmc.org/abstract/PMC/6145169

cites work

Varying body mass index cutoff points to describe overweight prevalence among U.S. adults: NHANES III (1988 to 1994).

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Crossref

reference URL

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21 January 2018

Actual causes of death in the United States

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21 January 2018

New approaches in the pharmacological treatment of obesity

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reference URL

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21 January 2018

Metabolic profiles of minimally absorbed orlistat in obese/overweight volunteers

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21 January 2018

Relationship between improved postprandial lipemia and low-density lipoprotein metabolism during treatment with tetrahydrolipstatin, a pancreatic lipase inhibitor

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Crossref

reference URL

https://api.crossref.org/works/10.1592%2FPHCO.20.4.270.34882

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21 January 2018

First clinical studies with orlistat: a short review

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Crossref

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21 January 2018

Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: a randomized controlled trial

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reference URL

https://api.crossref.org/works/10.1592%2FPHCO.20.4.270.34882

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21 January 2018

Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. European Multicentre Orlistat Study Group

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Role of orlistat in the treatment of obese patients with type 2 diabetes. A 1-year randomized double-blind study

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21 January 2018

The Influence of Orlistat on the Pharmacokinetics and Pharmacodynamics of Glyburide in Healthy Volunteers

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21 January 2018

Influence of orlistat on the regulation of gallbladder contraction in man: a randomized double-blind placebo-controlled crossover study

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Crossref

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https://api.crossref.org/works/10.1592%2FPHCO.20.4.270.34882

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21 January 2018

Treatment with orlistat reduces cardiovascular risk in obese patients

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of orlistat on the pharmacokinetics and pharmacodynamics of warfarin in healthy volunteers

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orlistat

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overweight and obesity in the United States: prevalence and trends, 1960-1994

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of interaction between orlistat and oral contraceptives

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orlistat, a lipase inhibitor, for weight maintenance after conventional dieting: a 1-y study

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of effect of orlistat on the bioavailability of a single dose of nifedipine extended-release tablets (Procardia XL) in healthy volunteers

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Is blockade of pancreatic lipase the answer?

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Orlistat (Ro 18-0647), a lipase inhibitor, in the treatment of human obesity: a multiple dose study

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

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inferred from PubMed ID database lookup

The effect of orlistat, an inhibitor of dietary fat absorption, on the absorption of vitamins A and E in healthy volunteers

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orlistat and weight loss

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of orlistat on the pharmacokinetics of phenytoin in healthy volunteers

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Medical hazards of obesity

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

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Review of limited systemic absorption of orlistat, a lipase inhibitor, in healthy human volunteers

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of the lipase inhibitor orlistat on the pharmacokinetics of four different antihypertensive drugs in healthy volunteers

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current estimates of the economic cost of obesity in the United States

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative Determination of Orlistat(Tetrahydrolipostatin, Ro 18-0647) in HumanPlasma by High-performance LiquidChromatography Coupled with Ion Spray Tandem Mass Spectrometry

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obesity

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A one-year trial to assess the value of orlistat in the management of obesity

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of orlistat, an inhibitor of dietary fat absorption, on the pharmacokinetics of beta-carotene in healthy volunteers

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of the gastrointestinal lipase inhibitor, orlistat, on serum lipids and lipoproteins in patients with primary hyperlipidaemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and tolerability of orlistat in the treatment of obesity: a 6-month dose-ranging study. Orlistat Dose-Ranging Study Group

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of pancreatic lipase in vitro by the covalent inhibitor tetrahydrolipstatin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mode of action of tetrahydrolipstatin: a derivative of the naturally occurring lipase inhibitor lipstatin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

United Kingdom Prospective Diabetes Study (UKPDS). 13: Relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with newly diagnosed non-insulin dependent diabetes followed for three years

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term systemic exposure of orlistat, a lipase inhibitor, and its metabolites in obese patients

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interaction of the lipase inhibitor orlistat with ethanol in healthy volunteers

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beneficial health effects of modest weight loss

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of reduced dietary fat absorption induced by orlistat on the pharmacokinetics of digoxin in healthy volunteers

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial studies in humans with the novel gastrointestinal lipase inhibitor Ro 18–0647 (tetrahydrolipstatin)

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of pancreatic and gastric lipases by tetrahydrolipstatin and alkyl-dithio-5-(2-nitrobenzoic acid). A kinetic study with 1,2-didecanoyl-sn-glycerol monolayers

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10730683

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1592/PHCO.20.4.270.34882

1 reference

stated in

Europe PubMed Central

PMC publication ID

6145169

retrieved

2 July 2019

reference URL

http://europepmc.org/abstract/PMC/6145169

PMC publication ID

6145169

1 reference

stated in

Europe PubMed Central

PMC publication ID

6145169

retrieved

2 July 2019

reference URL

http://europepmc.org/abstract/PMC/6145169

PubMed publication ID

10730683

1 reference

stated in

Europe PubMed Central

PMC publication ID

6145169

retrieved

2 July 2019

reference URL

http://europepmc.org/abstract/PMC/6145169

 

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