BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model. (Q33862879)

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2 February 2020

title

BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model (English)

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2 February 2020

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pilocytic astrocytoma

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1 reference

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2 February 2020

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2 February 2020

Charles G Eberhart

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2 February 2020

Kah Suan Lim

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2 February 2020

Julia M Kim

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2 February 2020

Alan Meeker

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2 February 2020

Guido Nikkhah

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2 February 2020

Jarek Maciaczyk

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2 February 2020

Ulf Kahlert

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2 February 2020

Deepali Jain

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2 February 2020

Eli Bar

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2 February 2020

Kenneth J Cohen

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2 February 2020

language of work or name

English

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publication date

1 June 2011

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2 February 2020

published in

Clinical Cancer Research

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volume

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issue

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2 February 2020

page(s)

3590-3599

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PI3K/AKT pathway alterations are associated with clinically aggressive and histologically anaplastic subsets of pilocytic astrocytoma

2 February 2020

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5 July 2018

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Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours

5 July 2018

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Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene

5 July 2018

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Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas

5 July 2018

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High-resolution, dual-platform aCGH analysis reveals frequent HIPK2 amplification and increased expression in pilocytic astrocytomas.

5 July 2018

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BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

5 July 2018

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Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assay

5 July 2018

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5 July 2018

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5 July 2018

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Integrative genomic approaches identify IKBKE as a breast cancer oncogene

5 July 2018

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Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence

5 July 2018

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Oncogene-Induced Senescence: Putting the Brakes on Tumor Development

5 July 2018

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

5 July 2018

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Spontaneous regression of residual low-grade cerebellar pilocytic astrocytomas in children

5 July 2018

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Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma

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29 October 2018

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Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.

29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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10.1158/1078-0432.CCR-10-3349

29 October 2018

Identifiers

DOI

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2 February 2020

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2 February 2020

PubMed publication ID

21636552

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