The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation (Q33853348)

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English	The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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author name string

M M Anderson

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

J R Requena

2

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Europe PubMed Central

PubMed publication ID

29 July 2017

J R Crowley

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

S R Thorpe

4

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Europe PubMed Central

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29 July 2017

J W Heinecke

5

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Europe PubMed Central

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29 July 2017

language of work or name

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publication date

1 July 1999

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Europe PubMed Central

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29 July 2017

Journal of Clinical Investigation

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Europe PubMed Central

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29 July 2017

104

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Europe PubMed Central

PubMed publication ID

29 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

103-113

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Role of the Phagocyte in Host-Parasite Interactions XXVII. Myeloperoxidase-H(2)O(2)-Cl-Mediated Aldehyde Formation and Its Relationship to Antimicrobial Activity.

1 reference

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Human neutrophils employ myeloperoxidase to convert alpha-amino acids to a battery of reactive aldehydes: a pathway for aldehyde generation at sites of inflammation

1 reference

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5 July 2018

Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to oxidize alpha-amino acids to a family of reactive aldehydes. Mechanistic studies identifying labile intermediates along the reaction pathway

1 reference

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5 July 2018

Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy

1 reference

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5 July 2018

Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.

1 reference

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5 July 2018

Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsatu

1 reference

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Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.

1 reference

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The role of oxidized lipoproteins in atherogenesis

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5 July 2018

RAGE: a novel cellular receptor for advanced glycation end products

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The mechanism of collagen cross-linking in diabetes: a puzzle nearing resolution

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BCL-2 expression or antioxidants prevent hyperglycemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells

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5 July 2018

Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus

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5 July 2018

Accumulation of Maillard reaction products in skin collagen in diabetes and aging

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5 July 2018

The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate

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5 July 2018

Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteins

1 reference

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5 July 2018

Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins.

1 reference

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5 July 2018

Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions

1 reference

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5 July 2018

Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose

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Nonenzymatic browning in vivo: possible process for aging of long-lived proteins

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Reaction of glycolaldehyde with proteins: latent crosslinking potential of alpha-hydroxyaldehydes

1 reference

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5 July 2018

Chlorination of taurine by human neutrophils. Evidence for hypochlorous acid generation

1 reference

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5 July 2018

Oxygen Metabolism and the Toxic Properties of Phagocytes

1 reference

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5 July 2018

Generation of nitrogen-chlorine oxidants by human phagocytes

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

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5 July 2018

Chloramines as intermediates of oxidation reaction of amino acids by myeloperoxidase.

1 reference

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5 July 2018

Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications

1 reference

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Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells

1 reference

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Comparative reactivities of various biological compounds with myeloperoxidase-hydrogen peroxide-chloride, and similarity of the oxidant to hypochlorite

1 reference

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5 July 2018

Biological interactions of alpha,beta-unsaturated aldehydes

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Structure elucidation of a senescence cross-link from human extracellular matrix. Implication of pentoses in the aging process

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Mechanisms of protection against damage mediated by the Maillard reaction in aging

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Role of oxidative stress in development of complications in diabetes

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Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

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Differential inactivation of Escherichia coli membrane dehydrogenases by a myeloperoxidase-mediated antimicrobial system

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Detection of 3-deoxyfructose and 3-deoxyglucosone in human urine and plasma: evidence for intermediate stages of the Maillard reaction in vivo

1 reference

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Studies on the chlorinating activity of myeloperoxidase

1 reference

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Reversible reductive alkylation of amino groups in proteins

1 reference

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Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.

1 reference

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1 reference

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Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

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based on heuristic

inferred from PubMed ID database lookup

Pathways of Formation of Glycoxidation Products during Glycation of Collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

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based on heuristic

inferred from PubMed ID database lookup

Cholesterol chlorohydrin synthesis by the myeloperoxidase-hydrogen peroxide-chloride system: potential markers for lipoproteins oxidatively damaged by phagocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between pentosidine levels in serum and urine and activity in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

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based on heuristic

inferred from PubMed ID database lookup

Role of protein-bound carbonyl groups in the formation of advanced glycation endproducts

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of oxidation of methyl linoleate in solution by vitamin E and vitamin C

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of diabetes and aging on carboxymethyllysine levels in human urine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enthalpy of decomposition of hydrogen peroxide by catalase at 25° C (with molar extinction coefficients of H2O2 solutions in the UV)

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of chlorination by human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p-Hydroxyphenylacetaldehyde is the major product of L-tyrosine oxidation by activated human phagocytes. A chloride-dependent mechanism for the conversion of free amino acids into reactive aldehydes by myeloperoxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystallization and properties of myeloperoxidase from normal human leukocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation and characterization of chloramines

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of N epsilon- carboxymethyllysine as a degradation product of fructoselysine in glycated protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased concentrations of serum pentosidine in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/10393704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI3042

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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