Ability of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4 (Q33851405)

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English	Ability of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

Ability of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4 (English)

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Europe PubMed Central

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29 July 2017

Simian immunodeficiency virus

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Michael Henry Malim

4

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Europe PubMed Central

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29 July 2017

author name string

R E Means

1

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Europe PubMed Central

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29 July 2017

T Matthews

2

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29 July 2017

J A Hoxie

3

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29 July 2017

T Kodama

5

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Europe PubMed Central

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29 July 2017

R C Desrosiers

6

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29 July 2017

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1 April 2001

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29 July 2017

Journal of Virology

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29 July 2017

75

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29 July 2017

8

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Europe PubMed Central

PubMed publication ID

29 July 2017

3903-3915

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Europe PubMed Central

PubMed publication ID

29 July 2017

Resistance of native, oligomeric envelope on simian immunodeficiency virus to digestion by glycosidases

1 reference

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The level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency viruses

1 reference

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Mechanisms for adaptation of simian immunodeficiency virus to replication in alveolar macrophages

1 reference

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V2 loop glycosylation of the human immunodeficiency virus type 1 SF162 envelope facilitates interaction of this protein with CD4 and CCR5 receptors and protects the virus from neutralization by anti-V3 loop and anti-CD4 binding site antibodies

1 reference

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Determinants of syncytium formation in microglia by human immunodeficiency virus type 1: role of the V1/V2 domains

1 reference

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Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein

1 reference

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Hypervariable region 3 residues of HIV type 1 gp120 involved in CCR5 coreceptor utilization: therapeutic and prophylactic implications

1 reference

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Functional dissection of CCR5 coreceptor function through the use of CD4-independent simian immunodeficiency virus strains

1 reference

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Study of the V3 loop as a target epitope for antibodies involved in the neutralization of primary isolates versus T-cell-line-adapted strains of human immunodeficiency virus type 1

1 reference

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T-tropic human immunodeficiency virus type 1 (HIV-1)-derived V3 loop peptides directly bind to CXCR-4 and inhibit T-tropic HIV-1 infection

1 reference

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Tropism, coreceptor use, and phylogenetic analysis of both the V3 loop and the protease gene of three novel HIV-1 group O isolates

1 reference

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Determinants of human immunodeficiency virus type 1 envelope glycoprotein activation by soluble CD4 and monoclonal antibodies

1 reference

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The antigenic structure of the HIV gp120 envelope glycoprotein

1 reference

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1 reference

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A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding

1 reference

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A role for carbohydrates in immune evasion in AIDS.

1 reference

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CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: consequences for virus entry and neutralization

1 reference

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28 July 2018

CXCR-4 Is Expressed by Primary Macrophages and Supports CCR5-Independent Infection by Dual-Tropic but Not T-Tropic Isolates of Human Immunodeficiency Virus Type 1

1 reference

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Changes in the extracellular envelope glycoprotein of variants that evolve during the course of simian immunodeficiency virus SIVMne infection affect neutralizing antibody recognition, syncytium formation, and macrophage tropism but not replication,

1 reference

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CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain

1 reference

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Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor

1 reference

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The V1/V2 Region of Human Immunodeficiency Virus Type 1 Modulates the Sensitivity to Neutralization by Soluble CD4 and Cellular Tropism

1 reference

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A new SIV co-receptor, STRL33

1 reference

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Differential utilization of CCR5 by macrophage and T cell tropic simian immunodeficiency virus strains

1 reference

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28 July 2018

CD4-independent infection by HIV-2 is mediated by fusin/CXCR4.

1 reference

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28 July 2018

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114881

28 July 2018

The V3 domain of SIVmac251 gp120 contains a linear neutralizing epitope

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114881

28 July 2018

A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114881

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The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

1 reference

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CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

1 reference

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HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1 reference

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Identification of a major co-receptor for primary isolates of HIV-1

1 reference

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HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1 reference

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Resistance to V3-directed neutralization caused by an N-linked oligosaccharide depends on the quaternary structure of the HIV-1 envelope oligomer

1 reference

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Differential role of V3-specific antibodies in neutralization assays involving primary and laboratory-adapted isolates of HIV type 1.

1 reference

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Effect of amino acid changes in the V1/V2 region of the human immunodeficiency virus type 1 gp120 glycoprotein on subunit association, syncytium formation, and recognition by a neutralizing antibody.

1 reference

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A single amino acid substitution in the V1 loop of human immunodeficiency virus type 1 gp120 alters cellular tropism.

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A PCR-derived library of random point mutations within the V3 region of simian immunodeficiency virus.

1 reference

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The "V3" domain is a determinant of simian immunodeficiency virus cell tropism.

1 reference

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Spontaneous substitutions in the vicinity of the V3 analog affect cell tropism and pathogenicity of simian immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114881

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Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114881

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Insertion of primary syncytium-inducing (SI) and non-SI envelope V3 loops in human immunodeficiency virus type 1 (HIV-1) LAI reduces neutralization sensitivity to autologous, but not heterologous, HIV-1 antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114881

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Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114881

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Isolation of T-cell tropic HTLV-III-like retrovirus from macaques

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Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: persistent infection of rhesus monkeys with molecularly cloned SIVmac

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Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein

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Evidence for rapid selection and deletion of HIV-1 subpopulations in vivo by V3-specific neutralizing antibody: a model of humoral-associated selection

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Characterization of the African HIV-1 isolate CBL-4 (RUT) by partial sequence analysis and virus neutralization with peptide antibody and antisense phosphate-methylated DNA.

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Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus

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Immunodominance and antigenic variation of the principal neutralization domain of HIV-1.

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Cooperativity of neutralizing antibodies directed against the V3 and CD4 binding regions of the human immunodeficiency virus gp120 envelope glycoprotein

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Complex determinants of macrophage tropism in env of simian immunodeficiency virus

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The principal neutralization determinant of simian immunodeficiency virus differs from that of human immunodeficiency virus type 1

1 reference

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V3 recombinants indicate a central role for CCR5 as a coreceptor in tissue infection by human immunodeficiency virus type 1.

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Neutralization sensitivity of cell culture-passaged simian immunodeficiency virus

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Specific N-linked and O-linked glycosylation modifications in the envelope V1 domain of simian immunodeficiency virus variants that evolve in the host alter recognition by neutralizing antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114881

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HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114881

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STRL33, A novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1

1 reference

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Plasmas from lymphocyte- and macrophage-tropic SIVmac-infected macaques have antibodies with a broader spectrum of virus neutralization activity in macrophage versus lymphocyte cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114881

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Functional role of the V1/V2 region of human immunodeficiency virus type 1 envelope glycoprotein gp120 in infection of primary macrophages and soluble CD4 neutralization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114881

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Immunodominant B-cell clones responsive to an HIV-1 neutralization and cell fusion inhibition epitope in chimpanzee-to-chimpanzee passages of HTLV-IIIB and LAV-1.

1 reference

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Titration and characterization of two rhesus-derived SIVmac challenge stocks

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https://pubmed.ncbi.nlm.nih.gov/11264379

12 December 2020

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10.1128/JVI.75.8.3903-3915.2001

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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