Small GTPases and regulation of cadherin dependent cell-cell adhesion (Q33850079)

29 July 2017

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title

Small GTPases and regulation of cadherin dependent cell-cell adhesion (English)

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29 July 2017

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Braga VM

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29 July 2017

language of work or name

English

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publication date

1 August 1999

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Journal of Clinical Pathology

29 July 2017

published in

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

197-202

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The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene

29 July 2017

cites work

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5 July 2018

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Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

5 July 2018

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Adhesive but not lateral E-cadherin complexes require calcium and catenins for their formation

5 July 2018

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5 July 2018

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Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion

5 July 2018

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Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly

5 July 2018

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E-Cadherin-dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27(KIP1)

5 July 2018

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Activation of the 41/43 kDa mitogen-activated protein kinase signaling pathway is required for hepatocyte growth factor-induced cell scattering

5 July 2018

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Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases

5 July 2018

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Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity

5 July 2018

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Activation of Rac and Cdc42 by integrins mediates cell spreading

5 July 2018

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Tyrosine phosphorylation and src family kinases control keratinocyte cell-cell adhesion.

5 July 2018

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Basal extracellular signal-regulated kinase activity modulates cell-cell and cell-matrix interactions

5 July 2018

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The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn

5 July 2018

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Integrin and cadherin synergy regulates contact inhibition of migration and motile activity

5 July 2018

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A causal role for E-cadherin in the transition from adenoma to carcinoma

5 July 2018

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Molecular and functional analysis of cadherin-based adherens junctions

5 July 2018

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Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K

5 July 2018

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Inhibition of Invasion of Epithelial Cells by Tiam1-Rac Signaling

5 July 2018

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Regulation of Cell–Cell Adhesion by Rac and Rho Small G Proteins in MDCK Cells

5 July 2018

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Rho-stimulated Contractility Contributes to the Fibroblastic Phenotype of Ras-transformed Epithelial Cells

5 July 2018

1 reference

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Rho GTPases and signaling networks

5 July 2018

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Role of Actin Polymerization and Adhesion to Extracellular Matrix in Rac- and Rho-induced Cytoskeletal Reorganization

5 July 2018

1 reference

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IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts

5 July 2018

1 reference

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E-cadherin engagement stimulates tyrosine phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

N-cadherin promotes adhesion between invasive breast cancer cells and the stroma.

5 July 2018

1 reference

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Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

5 July 2018

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

5 July 2018

1 reference

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Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Regulation of cell motility by mitogen-activated protein kinase

5 July 2018

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Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies

5 July 2018

1 reference

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Molecular interactions in cell adhesion complexes

5 July 2018

1 reference

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Quantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesion

5 July 2018

1 reference

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A role for cadherins in tissue formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Lateral dimerization is required for the homophilic binding activity of C-cadherin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Association between a transmembrane protein tyrosine phosphatase and the cadherin-catenin complex.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

The Dbl family of oncogenes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Regulated binding of PTP1B-like phosphatase to N-cadherin: control of cadherin-mediated adhesion by dephosphorylation of beta-catenin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Mechanism for transition from initial to stable cell-cell adhesion: kinetic analysis of E-cadherin-mediated adhesion using a quantitative adhesion assay

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Identification of a putative effector for Cdc42Hs with high sequence similarity to the RasGAP-related protein IQGAP1 and a Cdc42Hs binding partner with similarity to IQGAP2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Cell adhesion: the molecular basis of tissue architecture and morphogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

A role for Rho in Ras transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Assembly of the tight junction: the role of diacylglycerol

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Evidence that cadherins play a role in the downregulation of integrin expression that occurs during keratinocyte terminal differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Cadherin-mediated cell interactions are necessary for the activation of MyoD in Xenopus mesoderm

5 July 2018

1 reference

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Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor

5 July 2018

1 reference

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A truncated beta-catenin disrupts the interaction between E-cadherin and alpha-catenin: a cause of loss of intercellular adhesiveness in human cancer cell lines

5 July 2018

1 reference

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Structural basis of cell-cell adhesion by cadherins

5 July 2018

1 reference

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Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling

5 July 2018

1 reference

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Association of p120, a tyrosine kinase substrate, with E-cadherin/catenin complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Multiple Ras functions can contribute to mammalian cell transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Genetic and biochemical dissection of protein linkages in the cadherin-catenin complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Assembly of the cadherin-catenin complex in vitro with recombinant proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

An essential role for Rac in Ras transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia

5 July 2018

1 reference

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Plasticity in epithelial cell phenotype: modulation by expression of different cadherin cell adhesion molecules

5 July 2018

1 reference

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Modulation of scatter factor/hepatocyte growth factor activity by cell-substratum adhesion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Calcium-dependent cell-cell adhesion molecules (cadherins): subclass specificities and possible involvement of actin bundles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Cell binding function of E-cadherin is regulated by the cytoplasmic domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Purified N-cadherin is a potent substrate for the rapid induction of neurite outgrowth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Identification of a neural α-catenin as a key regulator of cadherin function and multicellular organization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Calcium-induced intercellular adhesion of keratinocytes does not involve accumulation of beta 1 integrins at cell-cell contacts and does not involve changes in the levels or phosphorylation of catenins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

A dominant inhibitory version of the small GTP-binding protein Rac disrupts cytoskeletal structures and inhibits developmental cell shape changes in Drosophila.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395699

Control of N-cadherin-mediated intercellular adhesion in migrating neural crest cells in vitro

29 October 2018

1 reference

12 December 2020

Regulation of cadherin-mediated adhesion by the small GTP-binding protein Rho in small cell lung carcinoma cells

1 reference

12 December 2020

p27 is involved in N-cadherin-mediated contact inhibition of cell growth and S-phase entry

1 reference

12 December 2020

Soluble 80-kd fragment of cell-CAM 120/80 disrupts cell-cell adhesion

1 reference

12 December 2020

Modulation of hepatocyte growth factor-induced scattering of HT29 colon carcinoma cells. Involvement of the MAPK pathway

1 reference

12 December 2020

The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted

1 reference

12 December 2020

Thrombin receptor ligation and activated rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets

1 reference

12 December 2020

Identifiers

DOI

10.1136/MP.52.4.197

1 reference

29 July 2017

1 reference

29 July 2017

1 reference