Reductions in amyloid-beta-derived neuroinflammation, with minocycline, restore cognition but do not significantly affect tau hyperphosphorylation (Q33856674)

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English	Reductions in amyloid-beta-derived neuroinflammation, with minocycline, restore cognition but do not significantly affect tau hyperphosphorylation	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

Reductions in amyloid-beta-derived neuroinflammation, with minocycline, restore cognition but do not significantly affect tau hyperphosphorylation (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

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Anna Parachikova

1

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Europe PubMed Central

PubMed publication ID

29 July 2017

Vitaly Vasilevko

2

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Europe PubMed Central

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29 July 2017

David H Cribbs

3

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Europe PubMed Central

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29 July 2017

Frank M LaFerla

4

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29 July 2017

Kim N Green

5

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29 July 2017

publication date

1 January 2010

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29 July 2017

Journal of Alzheimer's Disease

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Europe PubMed Central

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29 July 2017

21

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Europe PubMed Central

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29 July 2017

2

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29 July 2017

527-542

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Europe PubMed Central

PubMed publication ID

29 July 2017

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085054

5 July 2018

Astroglia in dementia and Alzheimer's disease.

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5 July 2018

Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085054

5 July 2018

Minocycline protects melanocytes against H2O2-induced cell death via JNK and p38 MAPK pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085054

5 July 2018

Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085054

5 July 2018

Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085054

5 July 2018

Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085054

5 July 2018

Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease

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5 July 2018

Minocycline modulates neuroinflammation independently of its antimicrobial activity in staphylococcus aureus-induced brain abscess

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085054

5 July 2018

Minocycline and sulforaphane inhibited lipopolysaccharide-mediated retinal microglial activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085054

5 July 2018

Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085054

5 July 2018

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085054

5 July 2018

Inflammatory changes parallel the early stages of Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085054

5 July 2018

Synaptic scaling mediated by glial TNF-alpha

1 reference

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5 July 2018

Minocycline affects microglia activation, Abeta deposition, and behavior in APP-tg mice

1 reference

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A dynamic relationship between intracellular and extracellular pools of Abeta

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Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice

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Are chemokines the third major system in the brain?

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5 July 2018

Minocycline as a neuroprotective agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085054

5 July 2018

Tau suppression in a neurodegenerative mouse model improves memory function

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Minocycline attenuates T cell and microglia activity to impair cytokine production in T cell-microglia interaction

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Neuroprotection by tetracyclines

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Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria

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Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

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The hippocampus mediates glucocorticoid-induced impairment of spatial memory retrieval: dependence on the basolateral amygdala

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Conditioned memory modulation, freezing, and avoidance as measures of amygdala-mediated conditioned fear

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Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085054

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Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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Innate and conditioned reactions to threat in rats with amygdaloid lesions

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Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease.

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Hippocampus, amygdala, and memory deficits in rats

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Elevated circulating tumor necrosis factor levels in Alzheimer's disease

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Tumor necrosis factor alters synaptic transmission in rat hippocampal slices

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10.3233/JAD-2010-100204

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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