Potent HIV-specific responses are enriched in a unique subset of CD8+ T cells that coexpresses CD4 on its surface (Q33843968)

29 July 2017

title

Potent HIV-specific responses are enriched in a unique subset of CD8+ T cells that coexpresses CD4 on its surface (English)

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29 July 2017

Andrew Zloza

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29 July 2017

Jason M Schenkel

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29 July 2017

Allan R Tenorio

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29 July 2017

Jeffrey A Martinson

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29 July 2017

Paul M Jeziorczak

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29 July 2017

Lena Al-Harthi

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29 July 2017

language of work or name

English

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publication date

21 August 2009

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29 July 2017

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inferred from page(s)

published in

Blood

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29 July 2017

volume

114

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29 July 2017

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29 July 2017

page(s)

3841-3853

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Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover

29 July 2017

cites work

1 reference

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Polyfunctional analysis of human t cell responses: importance in vaccine immunogenicity and natural infection

5 July 2018

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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

5 July 2018

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HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells.

5 July 2018

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The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens

5 July 2018

1 reference

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CD4 on CD8(+) T cells directly enhances effector function and is a target for HIV infection

5 July 2018

1 reference

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Central memory and effector memory T cell subsets: function, generation, and maintenance

5 July 2018

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T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis

5 July 2018

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CD8+ T cells that express CD4 on their surface (CD4dimCD8bright T cells) recognize an antigen-specific target, are detected in vivo, and can be productively infected by T-tropic HIV.

5 July 2018

1 reference

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Extrathymic CD4/CD8 double positive T cells

5 July 2018

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Costimulation of naive CD8(+) lymphocytes induces CD4 expression and allows human immunodeficiency virus type 1 infection.

5 July 2018

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Productive infection of neonatal CD8+ T lymphocytes by HIV-1.

5 July 2018

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Activation of CD8+ T lymphocytes through the T cell receptor turns on CD4 gene expression: implications for HIV pathogenesis

5 July 2018

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Emergence of double-positive CD4/CD8 cells from adult peripheral blood mononuclear cells infected with human T cell leukemia virus type I (HTLV-I).

5 July 2018

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T-cell abnormalities in patients with idiopathic thrombocytopenic purpura: the presence of OKT4+8+ cells

5 July 2018

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Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids.

5 July 2018

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Coexpression of T4 and T8 on peripheral blood T cells demonstrated by two-color fluorescence flow cytometry.

5 July 2018

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CD8+ cell anti-HIV activity correlates with the clinical state of the infected individual

5 July 2018

1 reference

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Intestinal double-positive CD4+CD8+ T cells are highly activated memory cells with an increased capacity to produce cytokines.

5 July 2018

1 reference

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Multiple populations of T lymphocytes are distinguished by the level of CD4 and CD8 coexpression and require individual consideration.

29 October 2018

1 reference

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The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration

29 October 2018

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Peripheral CD4(+)CD8(+) T cells are differentiated effector memory cells with antiviral functions.

29 October 2018

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Activation of CD8 T cells induces expression of CD4, which functions as a chemotactic receptor.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081354

Upregulation of CD4 on CD8+ T cells: CD4dimCD8bright T cells constitute an activated phenotype of CD8+ T cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081354

In vivo overexpression of Flt3 ligand expands and activates murine spleen natural killer dendritic cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081354

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

29 October 2018

1 reference

12 December 2020

Evaluation of T cell subsets in Behçet's syndrome using anti-T cell monoclonal antibodies

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12 December 2020

Circulating CD4+CD8+ cells in myasthenia gravis: supplementary immunological parameter for long-term prognosis

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12 December 2020

Cytofluorometric Identification of Two Populations of Double Positive (CD4+,CD8+) T Lymphocytes in Human Peripheral Blood

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12 December 2020

Circulating CD3+ CD4+ CD8+ T lymphocytes in multiple sclerosis

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12 December 2020

Phenotypic and functional abnormalities in the peripheral blood T-cells of patients with primary Sjogren's syndrome

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12 December 2020

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

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12 December 2020

Phenotypical heterogeneity of CD4+CD8+ double-positive chronic T lymphoid leukemia

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12 December 2020

Natural killer dendritic cells have both antigen presenting and lytic function and in response to CpG produce IFN-gamma via autocrine IL-12

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12 December 2020

10.1182/BLOOD-2009-02-202481

Identifiers

DOI

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29 July 2017

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29 July 2017

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