A novel TRPM8 agonist relieves dry eye discomfort (Q33837188)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28651550%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

title

A novel TRPM8 agonist relieves dry eye discomfort (English)

1 reference

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23 March 2020

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23 March 2020

Jee Myung Yang

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23 March 2020

Fengxian Li

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23 March 2020

Qin Liu

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23 March 2020

Marco Rüedi

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23 March 2020

Edward Tak Wei

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23 March 2020

Michael Lentsman

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23 March 2020

Hyo Seok Lee

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23 March 2020

Won Choi

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23 March 2020

Seong Jin Kim

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23 March 2020

publication date

26 June 2017

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23 March 2020

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23 March 2020

volume

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23 March 2020

issue

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23 March 2020

page(s)

101

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Patients with more severe symptoms of neuropathic ocular pain report more frequent and severe chronic overlapping pain conditions and psychiatric disease

23 March 2020

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Corneal Mechanical Thresholds Negatively Associate With Dry Eye and Ocular Pain Symptoms

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Therapeutic Strategies to Treat Dry Eye in an Aging Population

4 July 2018

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Transient receptor potential cation channel subfamily V member 1 expressing corneal sensory neurons can be subdivided into at least three subpopulations

4 July 2018

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4 July 2018

What Causes Eye Pain?

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TRPM8 is a neuronal osmosensor that regulates eye blinking in mice

4 July 2018

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Manipulating the murine lacrimal gland

4 July 2018

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The core mechanism of dry eye disease is inflammation

4 July 2018

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4 July 2018

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Lacrimal gland removal impairs sexual behavior in mice

4 July 2018

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Temperature-sensitive transient receptor potential channels in corneal tissue layers and cells

4 July 2018

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Why aren't there more pharmacotherapies for dry eye?

4 July 2018

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Tear fluid hyperosmolality increases nerve impulse activity of cold thermoreceptor endings of the cornea

4 July 2018

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Rethinking dry eye disease: a perspective on clinical implications

4 July 2018

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Emerging drugs for the treatment of dry eye disease

4 July 2018

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A sensory-labeled line for cold: TRPM8-expressing sensory neurons define the cellular basis for cold, cold pain, and cooling-mediated analgesia

4 July 2018

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Innervation of TRPV1-, PGP-, and CGRP-immunoreactive nerve fibers in the subepithelial layer of a whole mount preparation of the rat cornea

4 July 2018

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Menthol activation of corneal cool cells induces TRPM8-mediated lacrimation but not nociceptive responses in rodents

4 July 2018

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Wet mammals shake at tuned frequencies to dry.

4 July 2018

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The corneal pain system. Part I: the missing piece of the dry eye puzzle

4 July 2018

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Cold thermoreceptors, unexpected players in tear production and ocular dryness sensations

4 July 2018

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Computer vision syndrome: a review of ocular causes and potential treatments

4 July 2018

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Ocular surface wetness is regulated by TRPM8-dependent cold thermoreceptors of the cornea.

4 July 2018

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The economic burden of dry eye disease in the United States: a decision tree analysis

4 July 2018

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Cold-sensitive corneal afferents respond to a variety of ocular stimuli central to tear production: implications for dry eye disease

4 July 2018

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Expression of CXCL9, -10, -11, and CXCR3 in the tear film and ocular surface of patients with dry eye syndrome

4 July 2018

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Ophthalmic drug delivery: development and regulatory considerations.

4 July 2018

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Evaluation of novel dry eye model: preganglionic parasympathetic denervation in rabbit

4 July 2018

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The menthol receptor TRPM8 is the principal detector of environmental cold

4 July 2018

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Characterisation of TRPM8 as a pharmacophore receptor

4 July 2018

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Contribution of TRPM8 channels to cold transduction in primary sensory neurons and peripheral nerve terminals.

4 July 2018

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4 July 2018

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Botulinum toxin B-induced mouse model of keratoconjunctivitis sicca

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Effects of artificial tear temperature on corneal sensation and subjective comfort

4 July 2018

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Increased comfort and decreased inflammation of the eye by cooling after cataract surgery

4 July 2018

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AG-3–5: a chemical producing sensations of cold

4 July 2018

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4 July 2018

TRP channels and pain

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Conjunctival and corneal pneumatic sensitivity is associated with signs and symptoms of ocular dryness

21 January 2018

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Inhibition of TRPM8 channels reduces pain in the cold pressor test in humans.

21 January 2018

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Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch

21 January 2018

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Extraorbital lacrimal gland excision: a reproducible model of severe aqueous tear-deficient dry eye disease

21 January 2018

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Analysis of tear cytokines and clinical correlations in Sjögren syndrome dry eye patients and non-Sjögren syndrome dry eye patients

21 January 2018

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The lid wiper contains goblet cells and goblet cell crypts for ocular surface lubrication during the blink

21 January 2018

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A Novel Grading Method for Superficial Punctate Keratopathy Magnitude and Its Correlation With Corneal Epithelial Permeability

21 January 2018

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https://api.crossref.org/works/10.1186%2FS12886-017-0495-2

Reliability of drop size from multi-dose eye drop bottles: is it cause for concern?

21 January 2018

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Study of eye drops dispensing and dose variability by using plastic dropper tips

21 January 2018

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Ophthalmic drug delivery systems--recent advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12886-017-0495-2

TRP channels as emerging targets for pain therapeutics

21 January 2018

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12 December 2020

Tear function and ocular surface changes in noninsulin-dependent diabetes mellitus

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12 December 2020

Morphological and immunohistochemical characterization of the trigeminal ganglion neurons innervating the cornea and upper eyelid of the rat

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12 December 2020

Tear dynamics and dry eye

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12 December 2020

Management and therapy of dry eye disease: report of the Management and Therapy Subcommittee of the International Dry Eye WorkShop (2007)

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12 December 2020

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12 December 2020

Anatomy of the terminal nerves in the upper eyelid

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12 December 2020

The pathology of dry eye: the interaction between the ocular surface and lacrimal glands

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12 December 2020

The epidemiology of dry eye disease: report of the Epidemiology Subcommittee of the International Dry Eye WorkShop (2007)

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12 December 2020

Pharmacological aspects of shaking behavior produced by TRH, AG-3-5, and morphine withdrawal

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12 December 2020

Reliability and validity of the Ocular Surface Disease Index

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12 December 2020

Comparison of autologous serum and umbilical cord serum eye drops for dry eye syndrome

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12 December 2020

The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007)

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12 December 2020

10.1186/S12886-017-0495-2

Identifiers

DOI

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Dimensions Publication ID

23 March 2020

1 reference

https://scigraph.springernature.com/pub.10.1186/s12886-017-0495-2

9 September 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28651550%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

PubMed publication ID

28651550

1 reference

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