Combined troponin I Ser-150 and Ser-23/24 phosphorylation sustains thin filament Ca(2+) sensitivity and accelerates deactivation in an acidic environment. (Q33821210)

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English	Combined troponin I Ser-150 and Ser-23/24 phosphorylation sustains thin filament Ca(2+) sensitivity and accelerates deactivation in an acidic environment.	scientific article

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11 March 2020

Combined troponin I Ser-150 and Ser-23/24 phosphorylation sustains thin filament Ca(2+) sensitivity and accelerates deactivation in an acidic environment (English)

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11 March 2020

phosphorylation

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inferred from title

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11 March 2020

Shane D. Walton

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11 March 2020

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Bo Zhang

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11 March 2020

Elizabeth A Brundage

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11 March 2020

Sean C Little

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11 March 2020

Mark T Ziolo

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11 March 2020

Jonathan P Davis

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11 March 2020

Brandon J Biesiadecki

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11 March 2020

publication date

19 March 2014

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11 March 2020

Journal of Molecular and Cellular Cardiology

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11 March 2020

72

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11 March 2020

177-185

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11 March 2020

The rates of Ca2+ dissociation and cross-bridge detachment from ventricular myofibrils as reported by a fluorescent cardiac troponin C.

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28 July 2018

Engineered troponin C constructs correct disease-related cardiac myofilament calcium sensitivity

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28 July 2018

AMP-activated protein kinase phosphorylates cardiac troponin I at Ser-150 to increase myofilament calcium sensitivity and blunt PKA-dependent function.

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28 July 2018

AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes

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28 July 2018

A preferred AMPK phosphorylation site adjacent to the inhibitory loop of cardiac and skeletal troponin I

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28 July 2018

Antioxidant network expression abrogates oxidative posttranslational modifications in mice

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28 July 2018

Force relaxation and thin filament protein phosphorylation during acute myocardial ischemia

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28 July 2018

Structural and kinetic effects of PAK3 phosphorylation mimic of cTnI(S151E) on the cTnC-cTnI interaction in the cardiac thin filament

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28 July 2018

Removal of the cardiac troponin I N-terminal extension improves cardiac function in aged mice

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28 July 2018

Increased phosphorylation of tropomyosin, troponin I, and myosin light chain-2 after stretch in rabbit ventricular myocardium under physiological conditions.

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28 July 2018

Regulation of fibre contraction in a rat model of myocardial ischemia

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28 July 2018

Calcium sensitivity, force frequency relationship and cardiac troponin I: critical role of PKA and PKC phosphorylation sites

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28 July 2018

Effect of troponin I Ser23/24 phosphorylation on Ca2+-sensitivity in human myocardium depends on the phosphorylation background

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28 July 2018

In vivo phosphorylation site mapping in mouse cardiac troponin I by high resolution top-down electron capture dissociation mass spectrometry: Ser22/23 are the only sites basally phosphorylated.

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28 July 2018

Myofilament dysfunction in cardiac disease from mice to men.

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28 July 2018

Intracellular pH regulation in heart.

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28 July 2018

Multiplex kinase signaling modifies cardiac function at the level of sarcomeric proteins

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28 July 2018

Ca(2+) exchange with troponin C and cardiac muscle dynamics

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28 July 2018

Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle

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28 July 2018

Calcium, thin filaments, and the integrative biology of cardiac contractility

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28 July 2018

Ca2+, pH and the regulation of cardiac myofilament force and ATPase activity

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28 July 2018

Relation between high energy phosphate and lethal injury in myocardial ischemia in the dog.

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28 July 2018

Studies of acidosis in the ischaemic heart by phosphorus nuclear magnetic resonance

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28 July 2018

Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates.

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29 October 2018

Increased cross-bridge cycling kinetics after exchange of C-terminal truncated troponin I in skinned rat cardiac muscle

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29 October 2018

Histidine button engineered into cardiac troponin I protects the ischemic and failing heart.

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29 October 2018

Regulation of cardiac contractile function by troponin I phosphorylation

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29 October 2018

Troponin I phosphorylation plays an important role in the relaxant effect of beta-adrenergic stimulation in mouse hearts

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29 October 2018

An R111C polymorphism in wild turkey cardiac troponin I accompanying the dilated cardiomyopathy-related abnormal splicing variant of cardiac troponin T with potentially compensatory effects

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29 October 2018

Phosphorylation and mutation of human cardiac troponin I deferentially destabilize the interaction of the functional regions of troponin I with troponin C.

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29 October 2018

Protein kinase C and A sites on troponin I regulate myofilament Ca2+ sensitivity and ATPase activity in the mouse myocardium

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29 October 2018

Effects of phosphorylation and mutation R145G on human cardiac troponin I function.

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29 October 2018

Troponin I degradation and covalent complex formation accompanies myocardial ischemia/reperfusion injury

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29 October 2018

Phosphorylation of troponin I and phospholamban during catecholamine stimulation of rabbit heart

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7 January 2021

Troponin phosphorylation and regulatory function in human heart muscle: dephosphorylation of Ser23/24 on troponin I could account for the contractile defect in end-stage heart failure

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7 January 2021

The troponin C G159D mutation blunts myofilament desensitization induced by troponin I Ser23/24 phosphorylation

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7 January 2021

Breakdown and release of myofilament proteins during ischemia and ischemia/reperfusion in rat hearts: identification of degradation products and effects on the pCa-force relation

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7 January 2021

C-terminal truncation of cardiac troponin I causes divergent effects on ATPase and force: implications for the pathophysiology of myocardial stunning

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7 January 2021

Specific enhancement of sarcomeric response to Ca2+ protects murine myocardium against ischemia-reperfusion dysfunction

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Identifiers

10.1016/J.YJMCC.2014.03.010

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11 March 2020

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11 March 2020

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