Human immunodeficiency virus type 1 induces apoptosis in CD4(+) but not in CD8(+) T cells in ex vivo-infected human lymphoid tissue (Q33810879)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10933717%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Human immunodeficiency virus type 1 induces apoptosis in CD4(+) but not in CD8(+) T cells in ex vivo-infected human lymphoid tissue (English)

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9 November 2019

1 reference

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9 November 2019

N Malkevitch

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9 November 2019

L Margolis

series ordinal

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9 November 2019

publication date

1 September 2000

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9 November 2019

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9 November 2019

volume

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9 November 2019

issue

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9 November 2019

page(s)

8077-8084

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Exploiting the apoptotic process for management of HIV: are we there yet?

9 November 2019

cites work

1 reference

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Human immunodeficiency virus type 1 vpr induces apoptosis through caspase activation

4 July 2018

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Preferential coreceptor utilization and cytopathicity by dual-tropic HIV-1 in human lymphoid tissue ex vivo.

4 July 2018

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Lack of viral escape and defective in vivo activation of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes in rapidly progressive infection

4 July 2018

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4 July 2018

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Nef enhances human immunodeficiency virus replication and responsiveness to interleukin-2 in human lymphoid tissue ex vivo.

4 July 2018

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CCR5- and CXCR4-tropic HIV-1 are equally cytopathic for their T-cell targets in human lymphoid tissue.

4 July 2018

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CXCR4 utilization is sufficient to trigger CD4+ T cell depletion in HIV-1-infected human lymphoid tissue

4 July 2018

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CD4(+) T-lymphocyte depletion in human lymphoid tissue ex vivo is not induced by noninfectious human immunodeficiency virus type 1 virions.

4 July 2018

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Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes

4 July 2018

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Increased rates of CD4(+) and CD8(+) T lymphocyte turnover in simian immunodeficiency virus-infected macaques

4 July 2018

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Turnover of CD4+ and CD8+ T lymphocytes in HIV-1 infection as measured by Ki-67 antigen

4 July 2018

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4 July 2018

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4 July 2018

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Telomere length, telomerase activity, and replicative potential in HIV infection: analysis of CD4+ and CD8+ T cells from HIV-discordant monozygotic twins

4 July 2018

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4 July 2018

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Change in coreceptor use correlates with disease progression in HIV-1--infected individuals

4 July 2018

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Controlling HIV pathogenesis: the role of the noncytotoxic anti-HIV response of CD8+ T cells

4 July 2018

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Host factors and the pathogenesis of HIV-induced disease

4 July 2018

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Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2

4 July 2018

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Induction of bystander T cell proliferation by viruses and type I interferon in vivo

4 July 2018

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Predominant involvement of CD8+CD28- lymphocytes in human immunodeficiency virus-specific cytotoxic activity

4 July 2018

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Programmed cell death in peripheral lymphocytes from HIV-infected persons: increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression.

4 July 2018

1 reference

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Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells

4 July 2018

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Lymphocyte lifespans: homeostasis, selection and competition

4 July 2018

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Multifactorial nature of human immunodeficiency virus disease: implications for therapy

4 July 2018

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Programmed death of T cells in human immunodeficiency virus infection. No correlation with progression to disease

4 July 2018

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Direct and indirect mechanisms mediating apoptosis during HIV infection: contribution to in vivo CD4 T cell depletion

4 July 2018

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Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS.

4 July 2018

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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

4 July 2018

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Presence of CD3+CD8+Bcl-2(low) lymphocytes undergoing apoptosis and activated macrophages in lymph nodes of HIV-1+ patients

4 July 2018

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Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics

4 July 2018

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New concepts in the immunopathogenesis of HIV infection

4 July 2018

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Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

4 July 2018

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Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.

4 July 2018

1 reference

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Infection of human tonsil histocultures: a model for HIV pathogenesis

4 July 2018

1 reference

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Association between biological properties of human immunodeficiency virus variants and risk for AIDS and AIDS mortality

4 July 2018

1 reference

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Role of the human immunodeficiency virus type I envelope glycoprotein in cytopathic effect

4 July 2018

1 reference

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Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population

4 July 2018

1 reference

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Cell cycle dependent expression and stability of the nuclear protein detected by Ki-67 antibody in HL-60 cells

4 July 2018

1 reference

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Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112340

Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112340

Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112340

Rapid turnover of T lymphocytes in SIV-infected rhesus macaques.

30 October 2018

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Rapid CD4+ T-cell turnover in HIV-1 infection: a paradigm revisited

30 October 2018

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Monitoring early cellular responses in apoptosis is aided by the mitochondrial membrane protein-specific monoclonal antibody APO2.7.

30 October 2018

1 reference

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Experimental HIV infection of human lymphoid tissue: correlation of CD4+ T cell depletion and virus syncytium-inducing/non-syncytium-inducing phenotype in histocultures inoculated with laboratory strains and patient isolates of HIV type 1.

30 October 2018

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Development of a human thymic organ culture model for the study of HIV pathogenesis

30 October 2018

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Circulating HIV-specific CD8+ cytotoxic T cells express CD38 and HLA-DR antigens.

30 October 2018

1 reference

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Prospective Study of CD8+ Lymphocyte Activation in Relation to Viral Load in HIV-Infected Patients with >=400 CD4+ Lymphocytes per Microliter

30 October 2018

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Human neonatal thymic organ culture: an ex vivo model of thymocyte ontogeny and HIV-1 infection

30 October 2018

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12 December 2020

Failure of T-cell homeostasis preceding AIDS in HIV-1 infection

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12 December 2020

Correlates of apoptosis of CD4+ and CD8+ T cells in tonsillar tissue in HIV type 1 infection

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12 December 2020

Immune control of HIV-1 replication

1 reference

12 December 2020

Long-term telomere dynamics: modest increase of cell turnover in HIV-infected individuals followed for up to 14 years

1 reference

12 December 2020

Sexual Transmission and Propagation of SIV and HIV in Resting and Activated CD4+ T Cells

1 reference

12 December 2020

Immunopathogenic mechanisms of HIV infection

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12 December 2020

Resistance to HIV-1 infection: it's in the genes

1 reference

12 December 2020

Immunopathogenesis of HIV infection

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12 December 2020

T Cell Telomere Length in HIV-1 Infection: No Evidence for Increased CD4+ T Cell Turnover

1 reference

12 December 2020

Lymphocyte Trafficking and HIV Infection of Human Lymphoid Tissue in a Rotating Wall Vessel Bioreactor

1 reference

12 December 2020

T cell apoptosis in HIV infection: mechanisms and relevance for AIDS pathogenesis

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12 December 2020

Changes in blood CD8+ lymphocyte activation status and plasma HIV RNA levels during antiretroviral therapy

1 reference

12 December 2020

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67

1 reference

12 December 2020

HIV-specific cytotoxic T lymphocytes in seropositive individuals

1 reference

12 December 2020

Proliferation of normal and malignant human immature lymphoid cells

1 reference

12 December 2020

Programmed death of T cells in HIV-1 infection

1 reference

12 December 2020

Analysis of apoptosis in lymph nodes of HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden

1 reference

12 December 2020

10.1128/JVI.74.17.8077-8084.2000

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10933717%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10933717%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PubMed publication ID

10933717

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10933717%20AND%20SRC:MED&resulttype=core&format=json