Sensible use of antisense: how to use oligonucleotides as research tools (Q33818938)

29 July 2017

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title

Sensible use of antisense: how to use oligonucleotides as research tools (English)

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29 July 2017

Myers KJ

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29 July 2017

Dean NM

series ordinal

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29 July 2017

publication date

1 January 2000

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Trends in Pharmacological Sciences

29 July 2017

published in

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

19-23

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Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice

29 July 2017

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7 January 2021

Role of RNase H in hybrid-arrested translation by antisense oligonucleotides

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7 January 2021

Selective elimination of mRNAs in vivo: complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity

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7 January 2021

Identification and Characterization of Second-Generation Antisense Oligonucleotides

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7 January 2021

The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes

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7 January 2021

Antisense oligonucleotides: towards clinical trials

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7 January 2021

Antisense oligonucleotides as therapeutic agents--is the bullet really magical?

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7 January 2021

Intracellular availability of unmodified, phosphorothioated and liposomally encapsulated oligodeoxynucleotides for antisense activity

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7 January 2021

Oligodeoxynucleoside phosphorothioate stability in subcellular extracts, culture media, sera and cerebrospinal fluid

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7 January 2021

Stability of antisense DNA oligodeoxynucleotide analogs in cellular extracts and sera

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7 January 2021

Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression

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7 January 2021

A good antisense molecule is hard to find

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7 January 2021

Kinetics of G-quartet-mediated tetramer formation

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7 January 2021

CpG motifs in bacterial DNA trigger direct B-cell activation

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7 January 2021

Predicting antisense oligonucleotide inhibitory efficacy: a computational approach using histograms and thermodynamic indices

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Potent antisense oligonucleotides to the human multidrug resistance-1 mRNA are rationally selected by mapping RNA-accessible sites with oligonucleotide libraries

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7 January 2021

Selecting effective antisense reagents on combinatorial oligonucleotide arrays

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7 January 2021

Facilitating oligonucleotide delivery: helping antisense deliver on its promise

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7 January 2021

Improved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide

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7 January 2021

Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers

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7 January 2021

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

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7 January 2021

Electroporation enhances c-myc antisense oligodeoxynucleotide efficacy

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7 January 2021

Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells

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7 January 2021

Mechanism of oligonucleotide release from cationic liposomes

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7 January 2021

Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus

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7 January 2021

Sequence-independent induction of Sp1 transcription factor activity by phosphorothioate oligodeoxynucleotides

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7 January 2021

Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix

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7 January 2021

Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides

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7 January 2021

Evaluation of the Toxicity of ISIS 2302, a Phosphorothioate Oligonucleotide, in a 4-Week Study in CD-1 Mice

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7 January 2021

Stimulation of murine lymphocyte proliferation by a phosphorothioate oligonucleotide with antisense activity for herpes simplex virus

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7 January 2021

Pharmacology of Antisense Therapeutic Agents: Cancer and Inflammation

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7 January 2021

Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase

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7 January 2021

10.1016/S0165-6147(99)01420-0

Identifiers

DOI

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29 July 2017

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