Prediction and pathogenesis in type 1 diabetes. (Q33818896)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20412757%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

review article

1 reference

title

Prediction and pathogenesis in type 1 diabetes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20412757%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20412757%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Anette-G Ziegler

1 reference

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31 January 2020

language of work or name

English

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publication date

1 April 2010

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31 January 2020

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31 January 2020

volume

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31 January 2020

issue

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31 January 2020

page(s)

468-478

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Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin

31 January 2020

cites work

1 reference

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Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects

4 July 2018

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Zinc transporter 8 antibodies complement GAD and IA-2 antibodies in the identification and characterization of adult-onset autoimmune diabetes: Non Insulin Requiring Autoimmune Diabetes (NIRAD) 4.

4 July 2018

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4 July 2018

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4 July 2018

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APC dysfunction is correlated with defective suppression of T cell proliferation in human type 1 diabetes

4 July 2018

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The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells

4 July 2018

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Clinical heterogeneity in patients with FOXP3 mutations presenting with permanent neonatal diabetes

4 July 2018

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Validated protocol for FoxP3 reveals increased expression in type 1 diabetes patients

4 July 2018

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A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus

4 July 2018

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How the study of children with rheumatic diseases identified interferon-alpha and interleukin-1 as novel therapeutic targets

4 July 2018

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Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells

4 July 2018

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Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

4 July 2018

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The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

4 July 2018

1 reference

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Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade

4 July 2018

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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

4 July 2018

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A mini meta-analysis of studies on CD4+CD25+ T cells in human type 1 diabetes: report of the Immunology of Diabetes Society T Cell Workshop.

4 July 2018

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Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases

4 July 2018

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Extreme genetic risk for type 1A diabetes

4 July 2018

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Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

4 July 2018

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TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs

4 July 2018

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Newborn HLA-DR,DQ genotype screening: age- and ethnicity-specific type 1 diabetes risk estimates

4 July 2018

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IA-2 antibody prevalence and risk assessment of early insulin requirement in subjects presenting with type 2 diabetes (UKPDS 71).

4 July 2018

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Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetes

4 July 2018

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Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes.

4 July 2018

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Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus

4 July 2018

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Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes

4 July 2018

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Absolute risk of childhood-onset type 1 diabetes defined by human leukocyte antigen class II genotype: a population-based study in the United Kingdom

4 July 2018

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Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.

4 July 2018

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A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis

4 July 2018

1 reference

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A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

4 July 2018

1 reference

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Expansion and functional relevance of high-avidity myelin-specific CD4+ T cells in multiple sclerosis.

4 July 2018

1 reference

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Successful prospective prediction of type 1 diabetes in schoolchildren through multiple defined autoantibodies: an 8-year follow-up of the Washington State Diabetes Prediction Study

4 July 2018

1 reference

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

4 July 2018

1 reference

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Prediction of insulin-dependent diabetes mellitus in siblings of children with diabetes. A population-based study. The Childhood Diabetes in Finland Study Group

4 July 2018

1 reference

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The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

4 July 2018

1 reference

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Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

4 July 2018

1 reference

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Interactions of age, islet cell antibodies, insulin autoantibodies, and first-phase insulin response in predicting risk of progression to IDDM in ICA+ relatives: the ICARUS data set. Islet Cell Antibody Register Users Study

4 July 2018

1 reference

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Identification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragment

4 July 2018

1 reference

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Islet cell antigen 512 is a diabetes-specific islet autoantigen related to protein tyrosine phosphatases

4 July 2018

1 reference

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Effects of the second HLA-DQ haplotype on the association with childhood insulin-dependent diabetes mellitus

4 July 2018

1 reference

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HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM.

4 July 2018

1 reference

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First-degree relatives of patients with type I diabetes mellitus. Islet-cell antibodies and abnormal insulin secretion

4 July 2018

1 reference

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Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus

4 July 2018

1 reference

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Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

4 July 2018

1 reference

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Familial association between type 1 diabetes and other autoimmune and related diseases

4 July 2018

1 reference

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Switch from a dominant Th1-associated immune profile during the pre-diabetic phase in favour of a temporary increase of a Th3-associated and inflammatory immune profile at the onset of type 1 diabetes

30 October 2018

1 reference

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Higher FoxP3 mRNA expression in peripheral blood mononuclear cells of GAD65 or IA-2 autoantibody-positive compared with autoantibody-negative persons.

30 October 2018

1 reference

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Maternal type 1 diabetes reduces the risk of islet autoantibodies: relationships with birthweight and maternal HbA(1c).

30 October 2018

1 reference

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CD4+ T cells from type 1 diabetic and healthy subjects exhibit different thresholds of activation to a naturally processed proinsulin epitope

30 October 2018

1 reference

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Gene expression profiling of human pancreatic islets undergoing a simulated process of instant blood-mediated inflammatory reaction

30 October 2018

1 reference

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Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics.

30 October 2018

1 reference

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Genetic variation in PTPN22 corresponds to altered function of T and B lymphocytes

30 October 2018

1 reference

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Incidence of diabetes in youth in the United States

30 October 2018

1 reference

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Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients

30 October 2018

1 reference

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Comparative study of GAD65-specific CD4+ T cells in healthy and type 1 diabetic subjects

30 October 2018

1 reference

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The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease

30 October 2018

1 reference

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A functional polymorphism (1858C/T) in the PTPN22 gene is linked and associated with type I diabetes in multiplex families

30 October 2018

1 reference

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Insulin resistance is a risk factor for progression to type 1 diabetes

30 October 2018

1 reference

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Brief communication: early appearance of islet autoantibodies predicts childhood type 1 diabetes in offspring of diabetic parents

30 October 2018

1 reference

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Diabetes Antibody Standardization Program: First Assay Proficiency Evaluation

30 October 2018

1 reference

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Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes

30 October 2018

1 reference

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Predominantly recognized proinsulin T helper cell epitopes in individuals with and without islet cell autoimmunity

30 October 2018

1 reference

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Prevalence, characteristics and diabetes risk associated with transient maternally acquired islet antibodies and persistent islet antibodies in offspring of parents with type 1 diabetes

30 October 2018

1 reference

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Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

30 October 2018

1 reference

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Circulating CD4+CD25 high regulatory T cells and natural killer T cells in children with newly diagnosed type 1 diabetes or with diabetes-associated autoantibodies

30 October 2018

1 reference

12 December 2020

Evidence for in vivo primed and expanded autoreactive T cells as a specific feature of patients with type 1 diabetes

1 reference

12 December 2020

CD 127- and FoxP3+ expression on CD25+CD4+ T regulatory cells upon specific diabetogeneic stimulation in high-risk relatives of type 1 diabetes mellitus patients

1 reference

12 December 2020

Increased resistance to CD4+CD25hi regulatory T cell-mediated suppression in patients with type 1 diabetes

1 reference

12 December 2020

Concordance for islet autoimmunity among monozygotic twins

1 reference

12 December 2020

Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk

1 reference

12 December 2020

Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study

1 reference

12 December 2020

Immunoglobulin G insulin autoantibodies in BABYDIAB offspring appear postnatally: sensitive early detection using a protein A/G-based radiobinding assay

1 reference

12 December 2020

Early expression and high prevalence of islet autoantibodies for DR3/4 heterozygous and DR4/4 homozygous offspring of parents with Type I diabetes: the German BABYDIAB study

1 reference

12 December 2020

Early autoantibody responses in prediabetes are IgG1 dominated and suggest antigen-specific regulation

1 reference

12 December 2020

Human autoreactive CD4+ T cells from naive CD45RA+ and memory CD45RO+ subsets differ with respect to epitope specificity and functional antigen avidity

1 reference

12 December 2020

Transient antiislet autoantibodies: infrequent occurrence and lack of association with "genetic" risk factors

1 reference

12 December 2020

Proposed guidelines on screening for risk of type 1 diabetes

1 reference

12 December 2020

Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics

1 reference

12 December 2020

IDDM1 and multiple family history of type 1 diabetes combine to identify neonates at high risk for type 1 diabetes

1 reference

12 December 2020

Insulin Antibodies in Insulin-Dependent Diabetics Before Insulin Treatment

1 reference

12 December 2020

HLA-associated insulin autoantibody formation in newly diagnosed type I diabetic patients

1 reference

12 December 2020

Characterization of insulin autoantibodies in relatives of patients with type I diabetes

1 reference

12 December 2020

Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives

1 reference

12 December 2020

Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies

1 reference

12 December 2020

CD4+CD25high regulatory T cells in human autoimmune diabetes

1 reference

12 December 2020

Association analysis of the AIRE and insulin genes in Finnish type 1 diabetic patients

1 reference

12 December 2020

Type 1 diabetes risk assessment: improvement by follow-up measurements in young islet autoantibody-positive relatives

1 reference

12 December 2020

TEDDY--The Environmental Determinants of Diabetes in the Young: an observational clinical trial

1 reference

12 December 2020

Combined testing of antibody titer and affinity improves insulin autoantibody measurement: Diabetes Antibody Standardization Program

1 reference

12 December 2020

The CD4(+) regulatory T-cells is decreased in adults with latent autoimmune diabetes

1 reference

12 December 2020

No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes

1 reference

12 December 2020

GAD autoantibody affinity and epitope specificity identify distinct immunization profiles in children at risk for type 1 diabetes

1 reference

12 December 2020

10.1016/J.IMMUNI.2010.03.018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20412757%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20412757%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PubMed publication ID

20412757

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20412757%20AND%20SRC:MED&resulttype=core&format=json