Interleukin-18 as a therapeutic target in acute myocardial infarction and heart failure. (Q33801215)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

Interleukin-18 as a therapeutic target in acute myocardial infarction and heart failure (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

acute myocardial infarction

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Laura C O'Brien

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Eleonora Mezzaroma

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Benjamin W Van Tassell

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Carlo Marchetti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Antonio Abbate

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Stefano Toldo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

language of work or name

English

0 references

publication date

12 June 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

volume

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17 March 2020

page(s)

221-229

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

17 March 2020

start time

1 January 2014

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

cites work

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4 July 2018

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4 July 2018

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4 July 2018

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TIR8/SIGIRR is an Interleukin-1 Receptor/Toll Like Receptor Family Member with Regulatory Functions in Inflammation and Immunity

4 July 2018

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4 July 2018

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The Role of the NLRP3 Inflammasome in Fibrosis

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4 July 2018

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Membrane interleukin-18 revisits membrane IL-1α in T-helper type 1 responses

4 July 2018

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Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure

4 July 2018

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From risk factors to structural heart disease: the role of inflammation

4 July 2018

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The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse.

4 July 2018

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IL-37: a new anti-inflammatory cytokine of the IL-1 family.

4 July 2018

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β2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo

4 July 2018

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Interleukin 18 and coronary heart disease: prospective study and systematic review.

4 July 2018

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Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

4 July 2018

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Heart failure with preserved ejection fraction: pathophysiology, diagnosis, and treatment

4 July 2018

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Effects of interleukin-18 on cardiac fibroblast function and gene expression

4 July 2018

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4 July 2018

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Interleukin-18 as a Predictor of Future Events in Patients With Acute Coronary Syndromes

4 July 2018

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4 July 2018

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4 July 2018

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IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction

4 July 2018

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IL-18 induction of osteopontin mediates cardiac fibrosis and diastolic dysfunction in mice

4 July 2018

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Neutralization of interleukin-18 ameliorates ischemia/reperfusion-induced myocardial injury

4 July 2018

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Investigation of the effect of Interleukin-1 receptor antagonist (IL-1ra) on markers of inflammation in non-ST elevation acute coronary syndromes (The MRC-ILA-HEART Study).

4 July 2018

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Interleukin-18 knockout mice display maladaptive cardiac hypertrophy in response to pressure overload

4 July 2018

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Cytokine-induced modulation of cardiac function

4 July 2018

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Interleukin-18 is a pro-hypertrophic cytokine that acts through a phosphatidylinositol 3-kinase-phosphoinositide-dependent kinase-1-Akt-GATA4 signaling pathway in cardiomyocytes

4 July 2018

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Evidence for altered interleukin 18 (IL)-18 pathway in human heart failure.

4 July 2018

1 reference

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Beta-adrenergic stimulation induces interleukin-18 expression via beta2-AR, PI3K, Akt, IKK, and NF-kappaB.

4 July 2018

1 reference

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Differences in signaling pathways by IL-1beta and IL-18.

4 July 2018

1 reference

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Activation of intrinsic and extrinsic proapoptotic signaling pathways in interleukin-18-mediated human cardiac endothelial cell death

4 July 2018

1 reference

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Interleukin-18 and the risk of coronary heart disease in European men: the Prospective Epidemiological Study of Myocardial Infarction (PRIME).

4 July 2018

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Natriuretic peptides: markers or modulators of cardiac hypertrophy?

4 July 2018

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Inflammatory mediators and the failing heart: past, present, and the foreseeable future

4 July 2018

1 reference

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Role of interleukin-18 in host defense against disseminated Candida albicans infection

4 July 2018

1 reference

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Interleukin-18 induces rheumatoid arthritis synovial fibroblast CXC chemokine production through NFkappaB activation

4 July 2018

1 reference

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Beta-adrenergic axis and heart disease

4 July 2018

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Proinflammatory cytokines in heart disease

4 July 2018

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Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta

4 July 2018

1 reference

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Interleukin 18 in acute myocardial infarction

4 July 2018

1 reference

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Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18

4 July 2018

1 reference

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Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice

4 July 2018

1 reference

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Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells

4 July 2018

1 reference

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Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response

4 July 2018

1 reference

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Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling

4 July 2018

1 reference

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

4 July 2018

1 reference

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Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation

4 July 2018

1 reference

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Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069269

Involvement of Caspase-1 and Caspase-3 in the Production and Processing of Mature Human Interleukin 18 in Monocytic THP.1 Cells

4 July 2018

1 reference

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Purification and Characterization of the Human Interleukin-18 Receptor

4 July 2018

1 reference

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Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme

4 July 2018

1 reference

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Interferon-gamma-inducing factor, a novel cytokine, enhances Fas ligand-mediated cytotoxicity of murine T helper 1 cells

4 July 2018

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IFN-gamma-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones.

4 July 2018

1 reference

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IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP

4 July 2018

1 reference

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Cloning of a new cytokine that induces IFN-gamma production by T cells

4 July 2018

1 reference

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Assessment of the beta-adrenergic receptor pathway in the intact failing human heart: progressive receptor down-regulation and subsensitivity to agonist response

4 July 2018

1 reference

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Endotoxin-induced serum factor that stimulates gamma interferon production

4 July 2018

1 reference

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Formation of the inflammasome in acute myocarditis.

4 July 2018

1 reference

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Effect of hydrodynamics-based delivery of IL-18BP fusion gene on rat experimental autoimmune myocarditis

30 October 2018

1 reference

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Interleukin-1β blockade improves cardiac remodelling after myocardial infarction without interrupting the inflammasome in the mouse

30 October 2018

1 reference

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M-CSF induces the expression of a membrane-bound form of IL-18 in a subset of human monocytes differentiating in vitro toward macrophages

30 October 2018

1 reference

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Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction.

30 October 2018

1 reference

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Granzyme B is a novel interleukin-18 converting enzyme.

30 October 2018

1 reference

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Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study).

30 October 2018

1 reference

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The effect of daily administration of IL-18 on cardiac structure and function

30 October 2018

1 reference

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Interleukin-18 stimulates fibronectin expression in primary human cardiac fibroblasts via PI3K-Akt-dependent NF-kappaB activation

30 October 2018

1 reference

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Expression and alternative processing of IL-18 in human neutrophils

30 October 2018

1 reference

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Daily administration of interleukin-18 causes myocardial dysfunction in healthy mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069269

Interleukin-18 improves the early defence system against influenza virus infection by augmenting natural killer cell-mediated cytotoxicity

30 October 2018

1 reference

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Physiological levels of interleukin-18 stimulate multiple neutrophil functions through p38 MAP kinase activation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069269

Interleukin-18 is a strong predictor of cardiovascular death in stable and unstable angina

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069269

Increased myocardial expression of osteopontin in patients with advanced heart failure.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069269

Neutrophil proteinase 3-mediated induction of bioactive IL-18 secretion by human oral epithelial cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069269

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production

30 October 2018

1 reference

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A newly defined interleukin-1?

30 October 2018

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

Human mast cell chymase cleaves pro-IL-18 and generates a novel and biologically active IL-18 fragment

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

Interleukin-18 activates the IRAK-TRAF6 pathway in mouse EL-4 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

Expression of Interleukin-18 in Human Atherosclerotic Plaques and Relation to Plaque Instability

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

Increased circulating Interleukin-18 levels in centenarians with no signs of vascular disease: another paradox of longevity?

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

Increased cardiac IL-18 mRNA, pro-IL-18 and plasma IL-18 after myocardial infarction in the mouse; a potential role in cardiac dysfunction

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

Interleukin-18 induces production of proinflammatory cytokines in mice: no intermediate role for the cytokines of the tumor necrosis factor family and interleukin-1beta

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

Neutralization of IL-18 attenuates lipopolysaccharide-induced myocardial dysfunction

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

A Role for IL-18 in Neutrophil Activation

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

Catecholamines, cardiac beta-adrenergic receptors, and heart failure

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

Interleukin-18 induces human cardiac endothelial cell death via a novel signaling pathway involving NF-kappaB-dependent PTEN activation

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

Pharmacokinetics of IL-18 binding protein in healthy volunteers and subjects with rheumatoid arthritis or plaque psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

IL-18 contributes to host resistance against infection with Pseudomonas aeruginosa through induction of IFN-gamma production

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2014.00034

A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24804827

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2119/MOLMED.2014.00034

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

17 March 2020

1 reference

https://scigraph.springernature.com/pub.10.2119/molmed.2014.00034

9 September 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

PubMed publication ID

24804827

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24804827%20AND%20SRC:MED&resulttype=core&format=json