BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells (Q33806036)

29 July 2017

title

BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells (English)

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29 July 2017

Steffen Koschmieder

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Carsten Müller-Tidow

object named as

Carsten Müller-Tidow

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Joachim R Göthert

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Hubert Serve

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Tessa L Holyoake

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Daniel G Tenen

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Mirle Schemionek

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29 July 2017

Christian Elling

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29 July 2017

Ulrich Steidl

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29 July 2017

Nicole Bäumer

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29 July 2017

Ashley Hamilton

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29 July 2017

Tilmann Spieker

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29 July 2017

Martin Stehling

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29 July 2017

Amy Wagers

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29 July 2017

Claudia S Huettner

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29 July 2017

Lara Tickenbrock

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29 July 2017

Wolfgang E Berdel

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29 July 2017

language of work or name

English

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publication date

6 January 2010

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29 July 2017

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29 July 2017

volume

115

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29 July 2017

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29 July 2017

page(s)

3185-3195

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Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.

29 July 2017

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BCR/ABL promotes accumulation of chromosomal aberrations induced by oxidative and genotoxic stress

4 July 2018

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BCR/ABL, DNA damage and DNA repair: implications for new treatment concepts

4 July 2018

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Imaging hematopoietic precursor division in real time

4 July 2018

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4 July 2018

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4 July 2018

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Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies

4 July 2018

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Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

4 July 2018

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Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph+ leukemia in mice.

4 July 2018

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Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

4 July 2018

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Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL

4 July 2018

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4 July 2018

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BCR/ABL modifies the kinetics and fidelity of DNA double-strand breaks repair in hematopoietic cells

4 July 2018

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The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein

4 July 2018

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Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia

4 July 2018

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Different subsets of primary chronic myeloid leukemia stem cells engraft immunodeficient mice and produce a model of the human disease.

4 July 2018

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Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

4 July 2018

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The symmetry of initial divisions of human hematopoietic progenitors is altered only by the cellular microenvironment

4 July 2018

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A stem cell molecular signature

4 July 2018

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The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity

4 July 2018

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The kinetics and extent of engraftment of chronic myelogenous leukemia cells in non-obese diabetic/severe combined immunodeficiency mice reflect the phase of the donor's disease: an in vivo model of chronic myelogenous leukemia biology.

4 July 2018

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Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice

4 July 2018

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Culture purging in leukemia: past, present, and future

4 July 2018

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Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

4 July 2018

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Acute leukaemia in bcr/abl transgenic mice

4 July 2018

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Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage

4 July 2018

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IFNalpha activates dormant haematopoietic stem cells in vivo.

4 July 2018

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BMS-214662 potently induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitors

30 October 2018

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Molecular signature of CD34(+) hematopoietic stem and progenitor cells of patients with CML in chronic phase.

30 October 2018

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Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction

30 October 2018

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Outcome of four patients with chronic myeloid leukemia after imatinib mesylate discontinuation.

30 October 2018

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Pregnancy under treatment of imatinib and successful labor in a patient with chronic myelogenous leukemia (CML). Outcome of discontinuation of imatinib therapy after achieving a molecular remission

30 October 2018

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A mathematical model of hematopoiesis--I. Periodic chronic myelogenous leukemia.

30 October 2018

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In vivo characterization of bone marrow-derived fibroblasts recruited into fibrotic lesions.

30 October 2018

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MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858483

Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858483

Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858483

Discontinuation of imatinib therapy after achievement of complete molecular response in a Ph(+) CML patient treated while in long lasting complete cytogenetic remission (CCR) induced by interferon

30 October 2018

1 reference

12 December 2020

Tumor growth need not be driven by rare cancer stem cells

1 reference

12 December 2020

Bcr-Abl kinase domain mutations, drug resistance, and the road to a cure for chronic myeloid leukemia

1 reference

12 December 2020

Normal and chronic phase CML hematopoietic cells repopulate NOD/SCID bone marrow with different kinetics and cell lineage representation

1 reference

12 December 2020

Selective expansion of primitive normal hematopoietic cells in cytokine-supplemented cultures of purified cells from patients with chronic myeloid leukemia

1 reference

12 December 2020

Lineage involvement of stem cells bearing the philadelphia chromosome in chronic myeloid leukemia in the chronic phase as shown by a combination of fluorescence-activated cell sorting and fluorescence in situ hybridization

1 reference

12 December 2020

BCR/ABL oncogenic kinase promotes unfaithful repair of the reactive oxygen species-dependent DNA double-strand breaks

1 reference

12 December 2020

10.1182/BLOOD-2009-04-215376

Identifiers

DOI

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29 July 2017

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29 July 2017

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