Immunobiology of the TAM receptors (Q33796991)

29 July 2017

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title

Immunobiology of the TAM receptors (English)

1 reference

29 July 2017

Carla V Rothlin

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Greg Lemke

1 reference

29 July 2017

publication date

1 May 2008

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Nature Reviews Immunology

29 July 2017

published in

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

327-336

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Auto-oxidation and oligomerization of protein S on the apoptotic cell surface is required for Mer tyrosine kinase-mediated phagocytosis of apoptotic cells

29 July 2017

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4 July 2018

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Autophosphorylation docking site Tyr-867 in Mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccharide-inducible NF-kappaB transcriptional activat

4 July 2018

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4 July 2018

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4 July 2018

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Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Vitamin K-dependent proteins in Ciona intestinalis, a basal chordate lacking a blood coagulation cascade

4 July 2018

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Toll-like receptor (TLR) response tolerance: a key physiological "damage limitation" effect and an important potential opportunity for therapy.

4 July 2018

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Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cells

4 July 2018

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Tyro3 family-mediated cell entry of Ebola and Marburg viruses

4 July 2018

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Twist mediates suppression of inflammation by type I IFNs and Axl

4 July 2018

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4 July 2018

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Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases

4 July 2018

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Gas6/Axl signaling activates the phosphatidylinositol 3-kinase/Akt1 survival pathway to protect oligodendrocytes from tumor necrosis factor alpha-induced apoptosis

4 July 2018

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Clinical characterisation of a family with retinal dystrophy caused by mutation in the Mertk gene

4 July 2018

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Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia

4 July 2018

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Axl, a receptor tyrosine kinase, mediates flow-induced vascular remodeling

4 July 2018

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Phosphatidylserine recognition by phagocytes: a view to a kill

4 July 2018

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Clearance of Apoptotic Cells in Human SLE

4 July 2018

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Structural basis for Gas6-Axl signalling.

4 July 2018

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The role of gamma-carboxylation in the anti-apoptotic function of gas6

4 July 2018

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RETRACTED: A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control

4 July 2018

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Apoptosis and autoimmunity

4 July 2018

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Differential effects of CpG-DNA in Toll-like receptor-2/-4/-9 tolerance and cross-tolerance

4 July 2018

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Eph receptor signalling casts a wide net on cell behaviour

4 July 2018

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Evolution of the Class 2 cytokines and receptors, and discovery of new friends and relatives

4 July 2018

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Negative regulation of cytokine signaling and immune responses by SOCS proteins

4 July 2018

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4 July 2018

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Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses

4 July 2018

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Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma.

4 July 2018

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Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy

4 July 2018

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Activation of NK cell cytotoxicity

4 July 2018

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Impact of FASL-induced apoptosis in the elimination of tumor cells by NK cells

4 July 2018

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Gas6 inhibits apoptosis in vascular smooth muscle: role of Axl kinase and Akt

4 July 2018

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Expression profiling of IL-10-regulated genes in human monocytes and peripheral blood mononuclear cells from psoriatic patients during IL-10 therapy

4 July 2018

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Phagocytic removal of apoptotic spermatogenic cells by Sertoli cells: mechanisms and consequences

4 July 2018

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Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins

4 July 2018

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Coagulation, inflammation, and apoptosis: different roles for protein S and the protein S-C4b binding protein complex.

4 July 2018

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"Recruitment signals" from apoptotic cells: invitation to a quiet meal

4 July 2018

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The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

4 July 2018

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The growth arrest-specific gene product Gas6 promotes the survival of human oligodendrocytes via a phosphatidylinositol 3-kinase-dependent pathway.

4 July 2018

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Interleukin (IL)-15Rα–deficient Natural Killer Cells Survive in Normal but Not IL-15Rα–deficient Mice

4 July 2018

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In vivo survival and homeostatic proliferation of natural killer cells.

4 July 2018

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The protein kinase complement of the human genome

4 July 2018

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Serum-derived protein S binds to phosphatidylserine and stimulates the phagocytosis of apoptotic cells

4 July 2018

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IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

4 July 2018

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Functional significance of the perforin/granzyme cell death pathway

4 July 2018

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Crystal structure of a C-terminal fragment of growth arrest-specific protein Gas6. Receptor tyrosine kinase activation by laminin G-like domains

4 July 2018

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4 July 2018

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Essential role of Gas6 for glomerular injury in nephrotoxic nephritis.

4 July 2018

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Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase

4 July 2018

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A central role for death receptor-mediated apoptosis in the rejection of tumors by NK cells

4 July 2018

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Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family

4 July 2018

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Phagocytosis and clearance of apoptotic cells is mediated by MER.

4 July 2018

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Regulation of the natural killer cell receptor repertoire

4 July 2018

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Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.

4 July 2018

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Mechanism of stimulation of osteoclastic bone resorption through Gas6/Tyro 3, a receptor tyrosine kinase signaling, in mouse osteoclasts

4 July 2018

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Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa

4 July 2018

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The anticoagulant factor, protein S, is produced by cultured human vascular smooth muscle cells and its expression is up-regulated by thrombin

4 July 2018

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Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

4 July 2018

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Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat

4 July 2018

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Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells

4 July 2018

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Tyro-3 family receptors are essential regulators of mammalian spermatogenesis

4 July 2018

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A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock.

4 July 2018

1 reference

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Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases

4 July 2018

1 reference

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Interferon gamma production by natural killer (NK) cells and NK1.1+ T cells upon NKR-P1 cross-linking

4 July 2018

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The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases

4 July 2018

1 reference

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Participation of the retinal pigment epithelium in the rod outer segment renewal process

4 July 2018

1 reference

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Morphometrical analysis of Sertoli cell ultrastructure during the seminiferous epithelial cycle in rats

4 July 2018

1 reference

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An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system

4 July 2018

1 reference

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axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856445

Axl mediates vascular remodeling induced by deoxycorticosterone acetate-salt hypertension

4 July 2018

1 reference

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Interleukin-10 enhances the CD14-dependent phagocytosis of bacteria and apoptotic cells by human monocytes.

30 October 2018

1 reference

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MerTK activation during RPE phagocytosis in vivo requires alphaVbeta5 integrin

30 October 2018

1 reference

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The inflammation and coagulation cross-talk in patients with systemic lupus erythematosus.

30 October 2018

1 reference

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Lymphoblastic leukemia/lymphoma in mice overexpressing the Mer (MerTK) receptor tyrosine kinase

30 October 2018

1 reference

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Immunoexpression of Tyro 3 family receptors--Tyro 3, Axl, and Mer--and their ligand Gas6 in postnatal developing mouse testis

30 October 2018

1 reference

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In vivo analysis of phagocytosis of apoptotic cells by testicular Sertoli cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856445

Natural killer cell signaling pathways

30 October 2018

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The contribution of inherited and acquired thrombophilic defects, alone or combined with antiphospholipid antibodies, to venous and arterial thromboembolism in patients with systemic lupus erythematosus.

30 October 2018

1 reference

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An SH2 domain-dependent, phosphotyrosine-independent interaction between Vav1 and the Mer receptor tyrosine kinase: a mechanism for localizing guanine nucleotide-exchange factor action

30 October 2018

1 reference

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The mer receptor tyrosine kinase: expression and function suggest a role in innate immunity

30 October 2018

1 reference

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An RCS-like retinal dystrophy phenotype in mer knockout mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856445

Inhibitory effects of apoptotic cell ingestion upon endotoxin-driven myeloid dendritic cell maturation.

30 October 2018

1 reference

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Tyro 3 receptor tyrosine kinase and its ligand, Gas6, stimulate the function of osteoclasts

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856445

Requirement of gamma-carboxyglutamic acid residues for the biological activity of Gas6: contribution of endogenous Gas6 to the proliferation of vascular smooth muscle cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856445

TAM receptor function in the retinal pigment epithelium

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856445

RTK and TGF-β signaling pathways genes in the sea urchin genome

30 October 2018

1 reference

Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis

31 March 2020

1 reference

Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus

31 March 2020

1 reference

Induction of DAP12 phosphorylation, calcium mobilization, and cytokine secretion by Ly49H

31 March 2020

1 reference

Expression of IFN-gamma upon triggering of activating Ly49D NK receptors in vitro and in vivo: costimulation with IL-12 or IL-18 overrides inhibitory receptors

31 March 2020

1 reference

In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells

31 March 2020

1 reference

Elevated growth-arrest-specific protein 6 plasma levels in patients with severe sepsis

31 March 2020

1 reference

Prevalence of anti-protein S antibodies in patients with systemic lupus erythematosus

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI2303

1 reference

release_42pkpyrpi5awlci5sa3q43rgxi

29 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/42pkpyrpi5awlci5sa3q43rgxi

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

2856445

1 reference

29 July 2017

1 reference