Polybrominated diphenyl ethers induce developmental neurotoxicity in a human in vitro model: evidence for endocrine disruption (Q33789821)

29 July 2017

title

Polybrominated diphenyl ethers induce developmental neurotoxicity in a human in vitro model: evidence for endocrine disruption (English)

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29 July 2017

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1 reference

Ellen Fritsche

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29 July 2017

Timm Schreiber

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29 July 2017

Kathrin Gassmann

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29 July 2017

Christine Götz

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29 July 2017

Ulrike Hübenthal

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29 July 2017

Michaela Moors

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29 July 2017

Guido Krause

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29 July 2017

Hans F Merk

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29 July 2017

Ngoc-Ha Nguyen

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29 July 2017

Thomas S Scanlan

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29 July 2017

Josef Abel

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29 July 2017

Christine R Rose

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29 July 2017

publication date

1 April 2010

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Environmental Health Perspectives

29 July 2017

published in

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29 July 2017

volume

118

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29 July 2017

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29 July 2017

page(s)

572-578

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T-Screen as a tool to identify thyroid hormone receptor active compounds.

29 July 2017

cites work

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4 July 2018

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Mouse cerebellar astrocytes protect cerebellar granule neurons against toxicity of the polybrominated diphenyl ether (PBDE) mixture DE-71.

4 July 2018

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Cytotoxicity and gene expression profiling of two hydroxylated polybrominated diphenyl ethers in human H295R adrenocortical carcinoma cells.

4 July 2018

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Dietary exposure to 2,2',4,4'-tetrabromodiphenyl ether (PBDE-47) alters thyroid status and thyroid hormone-regulated gene transcription in the pituitary and brain

4 July 2018

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4 July 2018

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Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels

4 July 2018

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A technical mixture of 2,2',4,4'-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity

4 July 2018

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The polybrominated diphenyl ether mixture DE-71 is mildly estrogenic

4 July 2018

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Effects of PBDE-47 on cytotoxicity and genotoxicity in human neuroblastoma cells in vitro

4 July 2018

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Apoptosis induction on human hepatoma cells Hep G2 of decabrominated diphenyl ether (PBDE-209).

4 July 2018

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Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation.

4 July 2018

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Children show highest levels of polybrominated diphenyl ethers in a California family of four: a case study

4 July 2018

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Polybrominated diphenyl ether (PBDE) levels in an expanded market basket survey of U.S. food and estimated PBDE dietary intake by age and sex.

4 July 2018

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Increased "vigilance" of antioxidant mechanisms in neural stem cells potentiates their capability to resist oxidative stress

4 July 2018

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Neurotoxicity of the pentabrominated diphenyl ether mixture, DE-71, and hexabromocyclododecane (HBCD) in rat cerebellar granule cells in vitro

4 July 2018

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In vitro profiling of the endocrine-disrupting potency of brominated flame retardants.

4 July 2018

1 reference

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Mode of action: developmental thyroid hormone insufficiency--neurological abnormalities resulting from exposure to propylthiouracil

4 July 2018

1 reference

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Body burdens of polybrominated diphenyl ethers among urban anglers

4 July 2018

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Is house dust the missing exposure pathway for PBDEs? An analysis of the urban fate and human exposure to PBDEs

4 July 2018

1 reference

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Polychlorinated biphenyls disturb differentiation of normal human neural progenitor cells: clue for involvement of thyroid hormone receptors

4 July 2018

1 reference

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Polybrominated diphenyl ethers in house dust and clothes dryer lint.

4 July 2018

1 reference

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Polybrominated diphenyl ether flame retardants in the U.S. population: current levels, temporal trends, and comparison with dioxins, dibenzofurans, and polychlorinated biphenyls

4 July 2018

1 reference

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Brain-derived neurotrophic factor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Differential in vitro neurotoxicity of the flame retardant PBDE-99 and of the PCB Aroclor 1254 in human astrocytoma cells.

4 July 2018

1 reference

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Effects of polybrominated diphenyl ethers on basal and TCDD-induced ethoxyresorufin activity and cytochrome P450-1A1 expression in MCF-7, HepG2, and H4IIE cells.

4 July 2018

1 reference

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Different levels of polybrominated diphenyl ethers (PBDEs) and chlorinated compounds in breast milk from two U.K. Regions

4 July 2018

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Retrospective time-trend study of polybrominated diphenyl ether and polybrominated and polychlorinated biphenyl levels in human serum from the United States

4 July 2018

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The thyroid hormone receptor beta gene: structure and functions in the brain and sensory systems

4 July 2018

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Polybrominated diphenyl ethers (PBDEs) in U.S. mothers' milk

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Polybrominated diphenyl ethers in maternal and fetal blood samples

4 July 2018

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Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity

4 July 2018

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PBDEs in the San Francisco Bay Area: measurements in harbor seal blubber and human breast adipose tissue

4 July 2018

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Potent competitive interactions of some brominated flame retardants and related compounds with human transthyretin in vitro

4 July 2018

1 reference

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Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child

4 July 2018

1 reference

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Basic transcription element-binding protein (BTEB) is a thyroid hormone-regulated gene in the developing central nervous system. Evidence for a role in neurite outgrowth

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Thyroid hormone regulates reelin and dab1 expression during brain development

4 July 2018

1 reference

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Overexpression of the beta 1 thyroid receptor induces differentiation in neuro-2a cells

4 July 2018

1 reference

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Inhibition of neurogenic precursor proliferation by antisense alpha thyroid hormone receptor oligonucleotides

4 July 2018

1 reference

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GAP-43 as a plasticity protein in neuronal form and repair

4 July 2018

1 reference

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Neonatal hypothyroidism: Behavioral, thyroid hormonal and neuroanatomical effects

4 July 2018

1 reference

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Interleukin-7 (IL-7) and IL-7 splice variants affect differentiation of human neural progenitor cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Exposure to polybrominated diphenyl ethers 203 and 206 during the neonatal brain growth spurt affects proteins important for normal neurodevelopment in mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Polybrominated diphenyl ether (PBDE) flame retardants: environmental contamination, human body burden and potential adverse health effects.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Exposure to brominated flame retardant PBDE-99 affects cytoskeletal protein expression in the neonatal mouse cerebral cortex.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Hydroxylation increases the neurotoxic potential of BDE-47 to affect exocytosis and calcium homeostasis in PC12 cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Acute postnatal exposure to brominated diphenylether 47 delays neuromotor ontogeny and alters motor activity in mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

PBDE-47-induced oxidative stress, DNA damage and apoptosis in primary cultured rat hippocampal neurons

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

The role of mitochondrial and oxidative injury in BDE 47 toxicity to human fetal liver hematopoietic stem cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

ERK-dependent and -independent pathways trigger human neural progenitor cell migration

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Polybrominated diphenyl ethers (PBDEs) in U.S. computers and domestic carpet vacuuming: possible sources of human exposure

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Accumulation of PBDE-47 in primary cultures of rat neocortical cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Neurobehavioral derangements in adult mice receiving decabrominated diphenyl ether (PBDE 209) during a defined period of neonatal brain development

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Local and global spontaneous calcium events regulate neurite outgrowth and onset of GABAergic phenotype during neural precursor differentiation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Developmental exposure to brominated diphenyl ethers results in thyroid hormone disruption

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Effects of neonatal hypothyroidism on the expressions of growth cone proteins and axon guidance molecules related genes in the hippocampus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Developmental exposure to polychlorinated biphenyls exerts thyroid hormone-like effects on the expression of RC3/neurogranin and myelin basic protein messenger ribonucleic acids in the developing rat brain.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854737

Polybrominated diphenyl ethers and polychlorinated biphenyls in human adipose tissue from New York

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20368126

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Lack of alterations in thyroid hormones following exposure to polybrominated diphenyl ether 47 during a period of rapid brain development in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20368126

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1289/EHP.0901435

1 reference

29 July 2017

1 reference

29 July 2017

1 reference