BSAP can repress enhancer activity by targeting PU.1 function (Q33786904)

29 July 2017

title

BSAP can repress enhancer activity by targeting PU.1 function (English)

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29 July 2017

S Maitra

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29 July 2017

M Atchison

series ordinal

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29 July 2017

language of work or name

English

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publication date

1 March 2000

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Molecular and Cellular Biology

29 July 2017

published in

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

1911-1922

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PU.1, a shared transcriptional regulator of lymphoid and myeloid cell fates

29 July 2017

cites work

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AML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoter

4 July 2018

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Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1

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The highly conserved beta-hairpin of the paired DNA-binding domain is required for assembly of Pax-Ets ternary complexes

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c-Jun is a JNK-independent coactivator of the PU.1 transcription factor.

4 July 2018

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Redox potential controls the structure and DNA binding activity of the paired domain

4 July 2018

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4 July 2018

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PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors

4 July 2018

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The transcription factor NF-kappaB/p50 interacts with the blk gene during B cell activation

4 July 2018

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Normal myeloid development requires both the glutamine-rich transactivation domain and the PEST region of transcription factor PU.1 but not the potent acidic transactivation domain

4 July 2018

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Loss- and gain-of-function mutations reveal an important role of BSAP (Pax-5) at the start and end of B cell differentiation

4 July 2018

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A two-step mechanism for recruitment of Pip by PU.1.

4 July 2018

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Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments

4 July 2018

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Dependence of BSAP repressor and activator functions on BSAP concentration

4 July 2018

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Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor

4 July 2018

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Essential functions of Pax-5 (BSAP) in pro-B cell development.

4 July 2018

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In vivo occupancy of the kappa light chain enhancers in primary pro- and pre-B cells: a model for kappa locus activation

4 July 2018

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PU.1 can participate in an active enhancer complex without its transcriptional activation domain

4 July 2018

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Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities

4 July 2018

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An interleukin-2 signal relieves BSAP (Pax5)-mediated repression of the immunoglobulin J chain gene

4 July 2018

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The transcription factor PU.1 is involved in macrophage proliferation

4 July 2018

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Identification of an Spl-like element within the immunoglobulin kappa 3' enhancer necessary for maximal enhancer activity.

4 July 2018

1 reference

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A developmentally modulated chromatin structure at the mouse immunoglobulin kappa 3' enhancer

4 July 2018

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Spi-1/PU.1 transgenic mice develop multistep erythroleukemias

4 July 2018

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Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1

4 July 2018

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C-terminal activating and inhibitory domains determine the transactivation potential of BSAP (Pax-5), Pax-2 and Pax-8.

4 July 2018

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Regulation of 3' IgH enhancers by a common set of factors, including kappa B-binding proteins.

4 July 2018

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The 3' enhancer region determines the B/T specificity and pro-B/pre-B specificity of immunoglobulin V kappa-J kappa joining.

4 July 2018

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Characterization of functional domains within the multifunctional transcription factor, YY1.

4 July 2018

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Activation of transcription by PU.1 requires both acidic and glutamine domains

4 July 2018

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NF-HB (BSAP) is a repressor of the murine immunoglobulin heavy-chain 3' alpha enhancer at early stages of B-cell differentiation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Activation of the immunoglobulin kappa 3' enhancer in pre-B cells correlates with the suppression of a nuclear factor binding to a sequence flanking the active core

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Specific recognition of the blk promoter by the B-lymphoid transcription factor B-cell-specific activator protein

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

The transcription factor BSAP (NF-HB) is essential for immunoglobulin germ-line epsilon transcription

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

The murine Ig 3' alpha enhancer is a target site with repressor function for the B cell lineage-specific transcription factor BSAP (NF-HB, S alpha-BP).

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Pax5 (BSAP) regulates the murine immunoglobulin 3' alpha enhancer by suppressing binding of NF-alpha P, a protein that controls heavy chain transcription

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Activating transcription factor 1 and cyclic AMP response element modulator can modulate the activity of the immunoglobulin kappa 3' enhancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Inhibition of hematopoiesis by competitive binding of transcription factor PU.1.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

The B cell-specific transcription factor BSAP regulates B cell proliferation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

4 July 2018

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A new technique for the assay of infectivity of human adenovirus 5 DNA

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Spi-1 is a putative oncogene in virally induced murine erythroleukaemias.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

The putative oncogene Spi-1: murine chromosomal localization and transcriptional activation in murine acute erythroleukemias.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

The immunoglobulin kappa locus contains a second, stronger B-cell-specific enhancer which is located downstream of the constant region

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

The Sfpi-1 proviral integration site of Friend erythroleukemia encodes the ets-related transcription factor Pu.1.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Heterogeneously initiated transcription from the pre-B- and B-cell-specific mb-1 promoter: analysis of the requirement for upstream factor-binding sites and initiation site sequences

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

A novel lineage-specific nuclear factor regulates mb-1 gene transcription at the early stages of B cell differentiation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Functional characterization of the developmentally controlled immunoglobulin kappa 3' enhancer: regulation by Id, a repressor of helix-loop-helix transcription factors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

BLyF, a novel cell-type- and stage-specific regulator of the B-lymphocyte gene mb-1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Characterization of the human immunoglobulin kappa gene 3' enhancer: functional importance of three motifs that demonstrate B-cell-specific in vivo footprints

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Commitment to the monocytic lineage occurs in the absence of the transcription factor PU.1.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

PU. 1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

The transcription factor B cell-specific activator protein (BSAP) enhances both IL-4- and CD40-mediated activation of the human epsilon germline promoter

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

Regulation of human epsilon germline transcription: role of B-cell-specific activator protein

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110809

The PU.1 binding site is a cis-element that regulates pro-B/pre-B specificity of Vkappa-Jkappa joining

30 October 2018

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12 December 2020

Transcription factors in lymphocyte development--T and B cells get together

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12 December 2020

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

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12 December 2020

Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter

1 reference

12 December 2020

10.1128/MCB.20.6.1911-1922.2000

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DOI

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29 July 2017

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29 July 2017

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