Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78 (Q33778232)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20231467%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78 (English)

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19 January 2020

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19 January 2020

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19 January 2020

Marina S Gorbatyuk

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19 January 2020

Tessa Knox

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19 January 2020

Matthew M LaVail

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19 January 2020

Oleg S Gorbatyuk

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19 January 2020

Syed M Noorwez

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19 January 2020

Jonathan H Lin

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19 January 2020

Nicholas Muzyczka

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19 January 2020

language of work or name

English

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publication date

15 March 2010

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Proceedings of the National Academy of Sciences of the United States of America

19 January 2020

published in

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19 January 2020

volume

107

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19 January 2020

issue

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19 January 2020

page(s)

5961-5966

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Effect of an inducer of BiP, a molecular chaperone, on endoplasmic reticulum (ER) stress-induced retinal cell death

19 January 2020

cites work

1 reference

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Overexpression of endoplasmic reticulum-resident chaperone attenuates cardiomyocyte death induced by proteasome inhibition

4 July 2018

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Induction of BiP, an ER-resident protein, prevents the neuronal death induced by transient forebrain ischemia in gerbil

4 July 2018

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Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells

4 July 2018

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A molecular chaperone inducer protects neurons from ER stress

4 July 2018

1 reference

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IRE1 signaling affects cell fate during the unfolded protein response

4 July 2018

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Increased sensitivity to light-induced damage in a mouse model of autosomal dominant retinal disease

4 July 2018

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GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis

4 July 2018

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XIAP protection of photoreceptors in animal models of retinitis pigmentosa

4 July 2018

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Endoplasmic reticulum chaperones inhibit the production of amyloid-beta peptides.

4 July 2018

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Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors

4 July 2018

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Characterization of rhodopsin P23H-induced retinal degeneration in a Xenopus laevis model of retinitis pigmentosa

4 July 2018

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Mechanisms of cell death in rhodopsin retinitis pigmentosa: implications for therapy

4 July 2018

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ATF6 modulates SREBP2-mediated lipogenesis.

4 July 2018

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Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation

4 July 2018

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Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation

4 July 2018

1 reference

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ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

4 July 2018

1 reference

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The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation.

4 July 2018

1 reference

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Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78

4 July 2018

1 reference

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Unfolding retinal dystrophies: a role for molecular chaperones?

4 July 2018

1 reference

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Mutant rhodopsin transgene expression on a null background

4 July 2018

1 reference

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Ribozyme rescue of photoreceptor cells in P23H transgenic rats: long-term survival and late-stage therapy.

4 July 2018

1 reference

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Novel rhodopsin mutations Gly114Val and Gln184Pro in dominant retinitis pigmentosa.

4 July 2018

1 reference

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Stress protein GRP78 prevents apoptosis induced by calcium ionophore, ionomycin, but not by glycosylation inhibitor, tunicamycin, in human prostate cancer cells

4 July 2018

1 reference

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Overexpression of BiP in tobacco alleviates endoplasmic reticulum stress

4 July 2018

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Structure and function in rhodopsin: correct folding and misfolding in two point mutants in the intradiscal domain of rhodopsin identified in retinitis pigmentosa

4 July 2018

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Epitope tagging of the human endoplasmic reticulum HSP70 protein, BiP, to facilitate analysis of BiP--substrate interactions.

4 July 2018

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Mutation spectrum of the rhodopsin gene among patients with autosomal dominant retinitis pigmentosa

4 July 2018

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The tobacco luminal binding protein is encoded by a multigene family

4 July 2018

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Transgenic mice with a rhodopsin mutation (Pro23His): a mouse model of autosomal dominant retinitis pigmentosa

4 July 2018

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Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders.

4 July 2018

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Activation of endoplasmic reticulum stress in degenerating photoreceptors of the rd1 mouse

30 October 2018

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Multiple vulnerability of photoreceptors to mesopic ambient light in the P23H transgenic rat.

30 October 2018

1 reference

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Caspase-independent photoreceptor apoptosis in vivo and differential expression of apoptotic protease activating factor-1 and caspase-3 during retinal development

30 October 2018

1 reference

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A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system

30 October 2018

1 reference

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Functional abnormalities in transgenic mice expressing a mutant rhodopsin gene

30 October 2018

1 reference

12 December 2020

Immunoglobulin binding protein (BiP) function is required to protect cells from endoplasmic reticulum stress but is not required for the secretion of selective proteins

1 reference

12 December 2020

BiP, a major chaperone protein of the endoplasmic reticulum lumen, plays a direct and important role in the storage of the rapidly exchanging pool of Ca2+

1 reference

12 December 2020

Opsin localization and rhodopsin photochemistry in a transgenic mouse model of retinitis pigmentosa

1 reference

12 December 2020

That which does not kill me makes me stronger: adapting to chronic ER stress

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0911991107

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20231467%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

1 reference

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19 January 2020

PubMed publication ID

20231467

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