Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma (Q33752141)

29 July 2017

title

Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma (English)

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29 July 2017

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Martin Hrabě de Angelis

Martin Hrabě de Angelis

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Valérie Gailus-Durner

Valerie Gailus-Durner

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Simon Blank

Simon Blank

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Carsten B Schmidt-Weber

Carsten B Schmidt-Weber

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author name string

Antonio Aguilar-Pimentel

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29 July 2017

Anke Graessel

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29 July 2017

Francesca Alessandrini

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29 July 2017

Helmut Fuchs

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29 July 2017

Valerie Gailus-Durner

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29 July 2017

Dennis Russkamp

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29 July 2017

Adam Chaker

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29 July 2017

Markus Ollert

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29 July 2017

Jan Gutermuth

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29 July 2017

language of work or name

English

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publication date

1 June 2017

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29 July 2017

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

e0178563

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Creative Commons Attribution 4.0 International

29 July 2017

start time

1 June 2017

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April 2022 Public Data File from Crossref

copyrighted

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cites work

Tolerogenic Dendritic Cells Generated with Tofacitinib Ameliorate Experimental Autoimmune Encephalomyelitis through Modulation of Th17/Treg Balance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Impact of tofacitinib treatment on human B-cells in vitro and in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Janus kinase (JAK) inhibitors in the treatment of inflammatory and neoplastic diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

The Use of Adjuvants for Enhancing Allergen Immunotherapy Efficacy.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Mechanisms of allergen-specific immunotherapy and immune tolerance to allergens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

The JAK-STAT pathway: impact on human disease and therapeutic intervention

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Mechanisms of allergen-specific immunotherapy: multiple suppressor factors at work in immune tolerance to allergens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Fate of lymphocytes after withdrawal of tofacitinib treatment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Janus kinase 1/3 signaling pathways are key initiators of TH2 differentiation and lung allergic responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Reversal of CD8 T-cell-mediated mucocutaneous graft-versus-host-like disease by the JAK inhibitor tofacitinib

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Guidelines for treatment of atopic eczema (atopic dermatitis) Part II.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Identification of innate IL-5-producing cells and their role in lung eosinophil regulation and antitumor immunity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Allergen-specific immunotherapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Suppression of Th2-driven airway inflammation by allergen immunotherapy is independent of B cell and Ig responses in mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Injection allergen immunotherapy for asthma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

The influence of IgG density and macrophage Fc (gamma) receptor cross-linking on phagocytosis and IL-10 production

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: immunopathogenesis and therapeutic implications.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Grass pollen immunotherapy induces Foxp3-expressing CD4+ CD25+ cells in the nasal mucosa

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

21 June 2018

Insect sting anaphylaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Allergen injection immunotherapy for seasonal allergic rhinitis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Immunological mechanisms of specific allergen immunotherapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Molecular mechanisms underlying FOXP3 induction in human T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Fluticasone propionate increases CD4CD25 T regulatory cell suppression of allergen-stimulated CD4CD25 T cells by an IL-10-dependent mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

The IL-4 and IL-5 genes are closely linked and are part of a cytokine gene cluster on mouse chromosome 11

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5453633

Antigen specific immunotherapy generates CD27(+) CD35(+) tolerogenic dendritic cells

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0178563

Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0178563

Specific CD8 T cells in IgE-mediated allergy correlate with allergen dose and allergic phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0178563

Introducing the German Mouse Clinic: open access platform for standardized phenotyping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0178563

Effects of ultrafine carbon particle inhalation on allergic inflammation of the lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0178563

Allergen immunotherapy induces a suppressive memory response mediated by IL-10 in a mouse asthma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0178563

Modulating macrophage function with IgG immune complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0178563

The pharmacokinetics, metabolism, and clearance mechanisms of tofacitinib, a janus kinase inhibitor, in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0178563

Effects of Janus kinase inhibitor tofacitinib on circulating serum amyloid A and interleukin-6 during treatment for rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0178563

IL-4 enhances IL-10 gene expression in murine Th2 cells in the absence of TCR engagement

21 January 2018

1 reference

12 December 2020

Long-term efficacy of allergen immunotherapy: what do we expect?

1 reference

12 December 2020

The Jak inhibitor CP-690,550 preserves the function of CD4CD25FoxP3 regulatory T cells and inhibits effector T cells

1 reference

12 December 2020

Inhibitory effects of cyclosporine on human regulatory T cells in vitro

1 reference

12 December 2020

Proinflammatory mediator–induced reversal of CD4+,CD25+ regulatory T cell–mediated suppression in rheumatoid arthritis

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0178563

Identifiers

DOI

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29 July 2017

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29 July 2017

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