First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder. (Q33730680)

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English	First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder.	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

title

First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder (English)

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stated in

Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

author

Emily E Bullough

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4

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Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

Kenneth Boucher

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6

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Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

Leonard Milstone

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13

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Leonard M Milstone

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Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

author name string

Sancy A Leachman

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1

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Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

Robyn P Hickerson

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2

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Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

Mary E Schwartz

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3

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Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

Stephen L Hutcherson

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5

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Europe PubMed Central

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2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

C David Hansen

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7

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2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

Mark J Eliason

series ordinal

8

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Europe PubMed Central

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2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

G Susan Srivatsa

series ordinal

9

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Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

Douglas J Kornbrust

series ordinal

10

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Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

Frances Jd Smith

series ordinal

11

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Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

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12 February 2020

Wh Irwin McLean

series ordinal

12

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Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

Roger L Kaspar

series ordinal

14

1 reference

stated in

Europe PubMed Central

PMC publication ID

2839285

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

publication date

24 November 2009

1 reference

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Europe PubMed Central

PMC publication ID

2839285

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

published in

Molecular Therapy

1 reference

stated in

Europe PubMed Central

PMC publication ID

2839285

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

volume

18

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Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

issue

2

1 reference

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Europe PubMed Central

PMC publication ID

2839285

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

page(s)

442-446

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Europe PubMed Central

PMC publication ID

2839285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

cites work

siRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model.

1 reference

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PubMed Central

reference URL

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21 June 2018

Knocking down barriers: advances in siRNA delivery

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21 June 2018

The promises and pitfalls of RNA-interference-based therapeutics

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21 June 2018

Stability study of unmodified siRNA and relevance to clinical use.

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839285

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21 June 2018

Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita.

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839285

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21 June 2018

The business of RNAi therapeutics

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21 June 2018

RNAi therapeutics: an update on delivery

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21 June 2018

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

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21 June 2018

Delivering silence: advancements in developing siRNA therapeutics.

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21 June 2018

Single-nucleotide-specific siRNA targeting in a dominant-negative skin model

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PubMed Central

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21 June 2018

Challenges in developing therapies for rare diseases including pachyonychia congenita

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839285

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21 June 2018

The genetic basis of pachyonychia congenita.

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PubMed Central

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21 June 2018

Clinical and pathological features of pachyonychia congenita

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PubMed Central

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21 June 2018

Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice

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21 June 2018

An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy

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Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV).

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retrieved

30 October 2018

Identifiers

DOI

10.1038/MT.2009.273

1 reference

stated in

Europe PubMed Central

PMC publication ID

2839285

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

PMC publication ID

2839285

1 reference

stated in

Europe PubMed Central

PMC publication ID

2839285

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

PubMed publication ID

19935778

1 reference

stated in

Europe PubMed Central

PMC publication ID

2839285

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935778%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 February 2020

ResearchGate publication ID

40029081

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