THE POTENTIATION OF THE RADIOPROTECTIVE EFFICACY OF TWO MEDICAL COUNTERMEASURES, GAMMA-TOCOTRIENOL AND AMIFOSTINE, BY A COMBINATION PROPHYLACTIC MODALITY. (Q33728050)

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English	THE POTENTIATION OF THE RADIOPROTECTIVE EFFICACY OF TWO MEDICAL COUNTERMEASURES, GAMMA-TOCOTRIENOL AND AMIFOSTINE, BY A COMBINATION PROPHYLACTIC MODALITY.	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

THE POTENTIATION OF THE RADIOPROTECTIVE EFFICACY OF TWO MEDICAL COUNTERMEASURES, GAMMA-TOCOTRIENOL AND AMIFOSTINE, BY A COMBINATION PROPHYLACTIC MODALITY. (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

author name string

Vijay K Singh

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Oluseyi O Fatanmi

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Stephen Y Wise

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Victoria L Newman

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Patricia L P Romaine

5

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Thomas M Seed

6

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

publication date

19 August 2016

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Radiation Protection Dosimetry

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

172

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

1-3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

302-310

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

γ-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Radioprotective Efficacy of Gamma-Tocotrienol in Nonhuman Primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Animal models for acute radiation syndrome drug discovery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Biologics as countermeasures for acute radiation syndrome: where are we now?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Radiation countermeasure agents: an update (2011-2014)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Colony-stimulating factors for the treatment of the hematopoietic component of the acute radiation syndrome (H-ARS): a review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Metformin exhibits radiation countermeasures efficacy when used alone or in combination with sulfhydryl containing drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Radioprotection of hematopoietic progenitors by low dose amifostine prophylaxis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Radioprotective efficacy of delta-tocotrienol, a vitamin E isoform, is mediated through granulocyte colony-stimulating factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Vitamin E: tocopherols and tocotrienols as potential radiation countermeasures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Gamma-tocotrienol, a radiation prophylaxis agent, induces high levels of granulocyte colony-stimulating factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

5-AED enhances survival of irradiated mice in a G-CSF-dependent manner, stimulates innate immune cell function, reduces radiation-induced DNA damage and induces genes that modulate cell cycle progression and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Identification of granulocyte colony-stimulating factor and interleukin-6 as candidate biomarkers of CBLB502 efficacy as a medical radiation countermeasure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Prevention and mitigation of acute radiation syndrome in mice by synthetic lipopeptide agonists of Toll-like receptor 2 (TLR2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Radiation Injury After a Nuclear Detonation: Medical Consequences and the Need for Scarce Resources Allocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Reduction of Radiation-Induced Vascular Nitrosative Stress by the Vitamin E Analog γ-Tocotrienol: Evidence of a Role for Tetrahydrobiopterin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

gamma-Tocotrienol ameliorates intestinal radiation injury and reduces vascular oxidative stress after total-body irradiation by an HMG-CoA reductase-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Amifostine: the first selective-target and broad-spectrum radioprotector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

TLR2 but not TLR4 signalling is critically involved in the inhibition of IFN-gamma-induced killing of mycobacteria by murine macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Tocotrienols: Vitamin E beyond tocopherols

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Radiation protectants: current status and future prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Role of cytokines and growth factors in radioprotection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Priority list of research areas for radiological nuclear threat countermeasures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Amifostine induces anaerobic metabolism and hypoxia-inducible factor 1 alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

p53 protein regulates the effects of amifostine on apoptosis, cell cycle progression, and cytoprotection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Amifostine: an update on its clinical status as a cytoprotectant in patients with cancer receiving chemotherapy or radiotherapy and its potential therapeutic application in myelodysplastic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Subcutaneous administration of amifostine during fractionated radiotherapy: a randomized phase II study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Dosing considerations with amifostine: a review of the literature and clinical experience.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Pharmacologic approaches to protection against radiation-induced lethality and other damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Toxicity of WR-2721 administered in single and multiple doses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Specific protection of different normal tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Therapeutic Use of Recombinant Human G-CSF (rhG-CSF) in a Canine Model of Sublethal and Lethal Whole-body Irradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Therapeutic administration of recombinant human granulocyte colony‐stimulating factor accelerates hemopoietic regeneration and enhances survival in a murine model of radiation‐induced myelosuppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

14 July 2018

Preferential radiation sensitization of prostate cancer in nude mice by nutraceutical antioxidant gamma-tocotrienol.

1 reference

https://api.crossref.org/works/10.1093%2FRPD%2FNCW223

21 January 2018

Alpha-tocopherol succinate protects mice from gamma-radiation by induction of granulocyte-colony stimulating factor.

1 reference

https://api.crossref.org/works/10.1093%2FRPD%2FNCW223

21 January 2018

Cytokine-based treatment of radiation injury: potential benefits after low-level radiation exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444681

30 October 2018

Comparative behavioral toxicity of four sulfhydryl radioprotective compounds in mice: WR-2721, cysteamine, diethyldithiocarbamate, and N-acetylcysteine

1 reference

https://pubmed.ncbi.nlm.nih.gov/27542813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of normal tissues from the cytotoxic effects of chemotherapy and radiation by amifostine (Ethyol): preclinical aspects

1 reference

https://pubmed.ncbi.nlm.nih.gov/27542813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Granulocyte colony-stimulating factor antibody abrogates radioprotective efficacy of gamma-tocotrienol, a promising radiation countermeasure

1 reference

https://pubmed.ncbi.nlm.nih.gov/27542813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of radiation-induced granulocyte colony-stimulating factor in recovery from whole body gamma-irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27542813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radioprotective efficacy of tocopherol succinate is mediated through granulocyte-colony stimulating factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/27542813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accuracy considerations in EPR dosimetry

1 reference

https://pubmed.ncbi.nlm.nih.gov/27542813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radioprotection and therapy of radiation injury with cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/27542813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical trials of WR-2721 prior to alkylating agent chemotherapy and radiotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/27542813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/RPD/NCW223

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

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