Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies (Q33726660)

28 July 2017

title

Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies (English)

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28 July 2017

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Eliezer Masliah

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28 July 2017

He-Jin Lee

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28 July 2017

Ji-Eun Suk

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28 July 2017

Christina Patrick

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28 July 2017

Eun-Jin Bae

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28 July 2017

Ji-Hoon Cho

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28 July 2017

Sangchul Rho

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28 July 2017

Daehee Hwang

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28 July 2017

Seung-Jae Lee

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28 July 2017

language of work or name

English

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publication date

13 January 2010

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Journal of Biological Chemistry

28 July 2017

published in

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28 July 2017

volume

285

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28 July 2017

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28 July 2017

page(s)

9262-9272

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describes a project that uses

28 July 2017

Cytoscape

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9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Tau-positive glial inclusions in progressive supranuclear palsy, corticobasal degeneration and Pick's disease

21 June 2018

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Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

21 June 2018

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alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 June 2018

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Frontal cortical synaptophysin in Lewy body diseases: relation to Alzheimer's disease and dementia

21 June 2018

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Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop

21 June 2018

1 reference

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Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter

21 June 2018

1 reference

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Neuropathological stageing of Alzheimer-related changes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Development of alpha-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Ion channel blockade attenuates aggregated alpha synuclein induction of microglial reactive oxygen species: relevance for the pathogenesis of Parkinson's disease.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Absence of alpha-synuclein mRNA expression in normal and multiple system atrophy oligodendroglia

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Alpha-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Severity of gliosis in Pick's disease and frontotemporal lobar degeneration: tau-positive glia differentiate these disorders.

30 October 2018

1 reference

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Adult mouse astrocytes degrade amyloid-beta in vitro and in situ

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Glial involvement in diffuse Lewy body disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Effects of Cerebrolysin on amyloid-beta deposition in a transgenic model of Alzheimer's disease.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Immunostimulation of rat primary astrocytes decreases intracellular ATP level

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838344

NACP/alpha-synuclein-positive filamentous inclusions in astrocytes and oligodendrocytes of Parkinson's disease brains

30 October 2018

1 reference

12 December 2020

1 reference

12 December 2020

Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in

1 reference

12 December 2020

Ultrastructural characterization of the tau-immunoreactive tubules in the oligodendroglial perikarya and their inner loop processes in progressive supranuclear palsy

1 reference

12 December 2020

Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.081125

1 reference

28 July 2017

1 reference

28 July 2017

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